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326 related items for PubMed ID: 23750247

  • 1. TWEAK-independent Fn14 self-association and NF-κB activation is mediated by the C-terminal region of the Fn14 cytoplasmic domain.
    Brown SA, Cheng E, Williams MS, Winkles JA.
    PLoS One; 2013; 8(6):e65248. PubMed ID: 23750247
    [Abstract] [Full Text] [Related]

  • 2. TWEAK/Fn14 promotes pro-inflammatory cytokine secretion in hepatic stellate cells via NF-κB/STAT3 pathways.
    Wang A, Zhang F, Xu H, Xu M, Cao Y, Wang C, Xu Y, Su M, Zhang M, Zhuge Y.
    Mol Immunol; 2017 Jul; 87():67-75. PubMed ID: 28411440
    [Abstract] [Full Text] [Related]

  • 3. Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosis.
    Dhruv H, Loftus JC, Narang P, Petit JL, Fameree M, Burton J, Tchegho G, Chow D, Yin H, Al-Abed Y, Berens ME, Tran NL, Meurice N.
    J Biol Chem; 2013 Nov 08; 288(45):32261-32276. PubMed ID: 24056367
    [Abstract] [Full Text] [Related]

  • 4. The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor-inducible 14 (Fn14) signaling system regulates glioma cell survival via NFkappaB pathway activation and BCL-XL/BCL-W expression.
    Tran NL, McDonough WS, Savitch BA, Sawyer TF, Winkles JA, Berens ME.
    J Biol Chem; 2005 Feb 04; 280(5):3483-92. PubMed ID: 15611130
    [Abstract] [Full Text] [Related]

  • 5. Fibroblast growth factor inducible (Fn14)-specific antibodies concomitantly display signaling pathway-specific agonistic and antagonistic activity.
    Salzmann S, Seher A, Trebing J, Weisenberger D, Rosenthal A, Siegmund D, Wajant H.
    J Biol Chem; 2013 May 10; 288(19):13455-66. PubMed ID: 23532848
    [Abstract] [Full Text] [Related]

  • 6. Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells.
    Roos A, Dhruv HD, Mathews IT, Inge LJ, Tuncali S, Hartman LK, Chow D, Millard N, Yin HH, Kloss J, Loftus JC, Winkles JA, Berens ME, Tran NL.
    Oncotarget; 2017 Feb 14; 8(7):12234-12246. PubMed ID: 28103571
    [Abstract] [Full Text] [Related]

  • 7. TWEAK binding to the Fn14 cysteine-rich domain depends on charged residues located in both the A1 and D2 modules.
    Brown SA, Hanscom HN, Vu H, Brew SA, Winkles JA.
    Biochem J; 2006 Jul 15; 397(2):297-304. PubMed ID: 16526941
    [Abstract] [Full Text] [Related]

  • 8. Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway.
    Brown SA, Ghosh A, Winkles JA.
    J Biol Chem; 2010 Jun 04; 285(23):17432-41. PubMed ID: 20385556
    [Abstract] [Full Text] [Related]

  • 9. Studies of binding of tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) to fibroblast growth factor inducible 14 (Fn14).
    Fick A, Lang I, Schäfer V, Seher A, Trebing J, Weisenberger D, Wajant H.
    J Biol Chem; 2012 Jan 02; 287(1):484-495. PubMed ID: 22081603
    [Abstract] [Full Text] [Related]

  • 10. The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation.
    Brown SA, Richards CM, Hanscom HN, Feng SL, Winkles JA.
    Biochem J; 2003 Apr 15; 371(Pt 2):395-403. PubMed ID: 12529173
    [Abstract] [Full Text] [Related]

  • 11. TWEAK/Fn14 promotes the proliferation and collagen synthesis of rat cardiac fibroblasts via the NF-кB pathway.
    Chen HN, Wang DJ, Ren MY, Wang QL, Sui SJ.
    Mol Biol Rep; 2012 Aug 15; 39(8):8231-41. PubMed ID: 22555979
    [Abstract] [Full Text] [Related]

  • 12. Regulation of fibroblast growth factor-inducible 14 (Fn14) expression levels via ligand-independent lysosomal degradation.
    Gurunathan S, Winkles JA, Ghosh S, Hayden MS.
    J Biol Chem; 2014 May 09; 289(19):12976-88. PubMed ID: 24652288
    [Abstract] [Full Text] [Related]

  • 13. TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor.
    Polek TC, Talpaz M, Darnay BG, Spivak-Kroizman T.
    J Biol Chem; 2003 Aug 22; 278(34):32317-23. PubMed ID: 12794080
    [Abstract] [Full Text] [Related]

  • 14. TWEAK/Fn14 interaction induces proliferation and migration in human airway smooth muscle cells via activating the NF-κB pathway.
    Zhu C, Zhang L, Liu Z, Li C, Bai Y.
    J Cell Biochem; 2018 Apr 22; 119(4):3528-3536. PubMed ID: 29143982
    [Abstract] [Full Text] [Related]

  • 15. Tumor necrosis factor-like weak inducer of apoptosis and fibroblast growth factor-inducible 14 mediate cerebral ischemia-induced poly(ADP-ribose) polymerase-1 activation and neuronal death.
    Haile WB, Echeverry R, Wu F, Guzman J, An J, Wu J, Yepes M.
    Neuroscience; 2010 Dec 29; 171(4):1256-64. PubMed ID: 20955770
    [Abstract] [Full Text] [Related]

  • 16. The TWEAK-Fn14 system as a potential drug target.
    Wajant H.
    Br J Pharmacol; 2013 Oct 29; 170(4):748-64. PubMed ID: 23957828
    [Abstract] [Full Text] [Related]

  • 17. TWEAK activation of the non-canonical NF-κB signaling pathway differentially regulates melanoma and prostate cancer cell invasion.
    Armstrong CL, Galisteo R, Brown SA, Winkles JA.
    Oncotarget; 2016 Dec 06; 7(49):81474-81492. PubMed ID: 27821799
    [Abstract] [Full Text] [Related]

  • 18. TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice.
    Karaca G, Swiderska-Syn M, Xie G, Syn WK, Krüger L, Machado MV, Garman K, Choi SS, Michelotti GA, Burkly LC, Ochoa B, Diehl AM.
    PLoS One; 2014 Dec 06; 9(1):e83987. PubMed ID: 24416188
    [Abstract] [Full Text] [Related]

  • 19. The interaction between tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 promotes the recruitment of neutrophils into the ischemic brain.
    Haile WB, Echeverry R, Wu J, Yepes M.
    J Cereb Blood Flow Metab; 2010 Jun 06; 30(6):1147-56. PubMed ID: 20068578
    [Abstract] [Full Text] [Related]

  • 20. Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation.
    Wilhelm A, Shepherd EL, Amatucci A, Munir M, Reynolds G, Humphreys E, Resheq Y, Adams DH, Hübscher S, Burkly LC, Weston CJ, Afford SC.
    J Pathol; 2016 May 06; 239(1):109-21. PubMed ID: 26924336
    [Abstract] [Full Text] [Related]

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