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219 related items for PubMed ID: 23777858

  • 1. Engineering Chinese hamster ovary (CHO) cells for producing recombinant proteins with simple glycoforms by zinc-finger nuclease (ZFN)-mediated gene knockout of mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat1).
    Sealover NR, Davis AM, Brooks JK, George HJ, Kayser KJ, Lin N.
    J Biotechnol; 2013 Aug 10; 167(1):24-32. PubMed ID: 23777858
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  • 2. Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.
    Fan L, Kadura I, Krebs LE, Hatfield CC, Shaw MM, Frye CC.
    Biotechnol Bioeng; 2012 Apr 10; 109(4):1007-15. PubMed ID: 22068567
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  • 3. CRISPR/Cas9 gene editing for the creation of an MGAT1-deficient CHO cell line to control HIV-1 vaccine glycosylation.
    Byrne G, O'Rourke SM, Alexander DL, Yu B, Doran RC, Wright M, Chen Q, Azadi P, Berman PW.
    PLoS Biol; 2018 Aug 10; 16(8):e2005817. PubMed ID: 30157178
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  • 9. Synthesis of bisected glycoforms of recombinant IFN-beta by overexpression of beta-1,4-N-acetylglucosaminyltransferase III in Chinese hamster ovary cells.
    Sburlati AR, Umaña P, Prati EG, Bailey JE.
    Biotechnol Prog; 1998 Aug 10; 14(2):189-92. PubMed ID: 9548768
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  • 11. Development of a highly-efficient CHO cell line generation system with engineered SV40E promoter.
    Fan L, Kadura I, Krebs LE, Larson JL, Bowden DM, Frye CC.
    J Biotechnol; 2013 Dec 10; 168(4):652-8. PubMed ID: 23994266
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  • 12. Improvement of the efficiency and quality in developing a new CHO host cell line.
    Huhn SC, Ou Y, Tang X, Jiang B, Liu R, Lin H, Du Z.
    Biotechnol Prog; 2021 Sep 10; 37(5):e3185. PubMed ID: 34142466
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  • 15. Anti-pig antibody adsorption efficacy of {alpha}-Gal carrying recombinant P-selectin glycoprotein ligand-1/immunoglobulin chimeras increases with core 2 {beta}1, 6-N-acetylglucosaminyltransferase expression.
    Liu J, Gustafsson A, Breimer ME, Kussak A, Holgersson J.
    Glycobiology; 2005 Jun 10; 15(6):571-83. PubMed ID: 15625182
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  • 16. Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins.
    Dorai H, Corisdeo S, Ellis D, Kinney C, Chomo M, Hawley-Nelson P, Moore G, Betenbaugh MJ, Ganguly S.
    Biotechnol Bioeng; 2012 Apr 10; 109(4):1016-30. PubMed ID: 22068683
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  • 17. Application of CRISPR/Cas9 Genome Editing to Improve Recombinant Protein Production in CHO Cells.
    Grav LM, la Cour Karottki KJ, Lee JS, Kildegaard HF.
    Methods Mol Biol; 2017 Apr 10; 1603():101-118. PubMed ID: 28493126
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  • 18. Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens.
    Li SW, Wright M, Healey JF, Hutchinson JM, O'Rourke S, Mesa KA, Lollar P, Berman PW.
    PLoS One; 2020 Apr 10; 15(5):e0233866. PubMed ID: 32470085
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