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363 related items for PubMed ID: 23786349

  • 1. Biological evaluation and molecular modelling study of podophyllotoxin derivatives as potent inhibitors of tubulin polymerization.
    Ma Y, Fang S, Li H, Han C, Lu Y, Zhao Y, Liu Y, Zhao C.
    Chem Biol Drug Des; 2013 Jul; 82(1):12-21. PubMed ID: 23786349
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of podophyllotoxin congeners as tubulin polymerization inhibitors.
    Kamal A, Srinivasa Reddy T, Polepalli S, Shalini N, Reddy VG, Subba Rao AV, Jain N, Shankaraiah N.
    Bioorg Med Chem; 2014 Oct 01; 22(19):5466-75. PubMed ID: 25131956
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of a series of podophyllotoxins derivatives as a class of potent antitubulin agents.
    Liu Y, Wei D, Zhao Y, Cheng W, Lu Y, Ma Y, Li X, Han C, Wei Y, Cao H, Zhao C.
    Bioorg Med Chem; 2012 Nov 01; 20(21):6285-95. PubMed ID: 23022053
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
    Wang G, Peng F, Cao D, Yang Z, Han X, Liu J, Wu W, He L, Ma L, Chen J, Sang Y, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2013 Nov 01; 21(21):6844-54. PubMed ID: 23993668
    [Abstract] [Full Text] [Related]

  • 5. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
    Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S.
    Bioorg Med Chem; 2014 May 01; 22(9):2714-23. PubMed ID: 24721832
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and anticancer activity of analogues of phenstatin, with a phenothiazine A-ring, as a new class of microtubule-targeting agents.
    Abuhaie CM, Bîcu E, Rigo B, Gautret P, Belei D, Farce A, Dubois J, Ghinet A.
    Bioorg Med Chem Lett; 2013 Jan 01; 23(1):147-52. PubMed ID: 23200248
    [Abstract] [Full Text] [Related]

  • 7. Investigation of podophyllotoxin esters as potential anticancer agents: synthesis, biological studies and tubulin inhibition properties.
    Shareef MA, Duscharla D, Ramasatyaveni G, Dhoke NR, Das A, Ummanni R, Srivastava AK.
    Eur J Med Chem; 2015 Jan 07; 89():128-37. PubMed ID: 25462233
    [Abstract] [Full Text] [Related]

  • 8. Molecular modelling studies on Arylthioindoles as potent inhibitors of tubulin polymerization.
    Coluccia A, Sabbadin D, Brancale A.
    Eur J Med Chem; 2011 Aug 07; 46(8):3519-25. PubMed ID: 21621885
    [Abstract] [Full Text] [Related]

  • 9. Design and synthesis of aminostilbene-arylpropenones as tubulin polymerization inhibitors.
    Kamal A, Kumar GB, Polepalli S, Shaik AB, Reddy VS, Reddy MK, Reddy ChR, Mahesh R, Kapure JS, Jain N.
    ChemMedChem; 2014 Nov 07; 9(11):2565-79. PubMed ID: 25146959
    [Abstract] [Full Text] [Related]

  • 10. Design and biological evaluation of novel tubulin inhibitors as antimitotic agents using a pharmacophore binding model with tubulin.
    Kim DY, Kim KH, Kim ND, Lee KY, Han CK, Yoon JH, Moon SK, Lee SS, Seong BL.
    J Med Chem; 2006 Sep 21; 49(19):5664-70. PubMed ID: 16970393
    [Abstract] [Full Text] [Related]

  • 11. Structure of 4'-demethylepipodophyllotoxin in complex with tubulin provides a rationale for drug design.
    Niu L, Wang Y, Wang C, Wang Y, Jiang X, Ma L, Wu C, Yu Y, Chen Q.
    Biochem Biophys Res Commun; 2017 Nov 04; 493(1):718-722. PubMed ID: 28864414
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and Biological evaluation of novel 4β-[(5-substituted)-1,2,3,4-tetrazolyl] podophyllotoxins as anticancer compounds.
    Hyder I, Yedlapudi D, Kalivendi SV, Khazir J, Ismail T, Nalla N, Miryala S, Sampath Kumar HM.
    Bioorg Med Chem Lett; 2015 Jul 15; 25(14):2860-3. PubMed ID: 26022842
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis, and biological evaluation of the first podophyllotoxin analogues as potential vascular-disrupting agents.
    Labruère R, Gautier B, Testud M, Seguin J, Lenoir C, Desbène-Finck S, Helissey P, Garbay C, Chabot GG, Vidal M, Giorgi-Renault S.
    ChemMedChem; 2010 Dec 03; 5(12):2016-25. PubMed ID: 20979080
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
    Wang ZZ, Sun WX, Wang X, Zhang YH, Qiu HY, Qi JL, Pang YJ, Lu GH, Wang XM, Yu FG, Yang YH.
    Chem Biol Drug Des; 2017 Aug 03; 90(2):236-243. PubMed ID: 28079286
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and biological evaluation of (E)-3-(3,4-dihydroxyphenyl)acrylylpiperazine derivatives as a new class of tubulin polymerization inhibitors.
    Yin Y, Qiao F, Jiang LY, Wang SF, Sha S, Wu X, Lv PC, Zhu HL.
    Bioorg Med Chem; 2014 Aug 01; 22(15):4285-92. PubMed ID: 24916028
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, molecular modeling and biological evaluation of guanidine derivatives as novel antitubulin agents.
    Qian Y, Zhang HJ, Lv PC, Zhu HL.
    Bioorg Med Chem; 2010 Dec 01; 18(23):8218-25. PubMed ID: 21036623
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of macrocyclic bisbibenzyl derivatives and their anticancer effects as anti-tubulin agents.
    Jiang J, Sun B, Wang YY, Cui M, Zhang L, Cui CZ, Wang YF, Liu XG, Lou HX.
    Bioorg Med Chem; 2012 Apr 01; 20(7):2382-91. PubMed ID: 22365913
    [Abstract] [Full Text] [Related]

  • 18. Inhibitors of tubulin polymerization: synthesis and biological evaluation of hybrids of vindoline, anhydrovinblastine and vinorelbine with thiocolchicine, podophyllotoxin and baccatin III.
    Passarella D, Giardini A, Peretto B, Fontana G, Sacchetti A, Silvani A, Ronchi C, Cappelletti G, Cartelli D, Borlak J, Danieli B.
    Bioorg Med Chem; 2008 Jun 01; 16(11):6269-85. PubMed ID: 18468444
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.
    Ruan BF, Lu X, Li TT, Tang JF, Wei Y, Wang XL, Zheng SL, Yao RS, Zhu HL.
    Bioorg Med Chem; 2012 Jan 15; 20(2):1113-21. PubMed ID: 22189271
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and anticancer activity of 2-benzylidene indanones through inhibiting tubulin polymerization.
    Prakasham AP, Saxena AK, Luqman S, Chanda D, Kaur T, Gupta A, Yadav DK, Chanotiya CS, Shanker K, Khan F, Negi AS.
    Bioorg Med Chem; 2012 May 01; 20(9):3049-57. PubMed ID: 22472045
    [Abstract] [Full Text] [Related]

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