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Journal Abstract Search


248 related items for PubMed ID: 23804523

  • 1. Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1.
    Meyer A, Vuorinen A, Zielinska AE, Strajhar P, Lavery GG, Schuster D, Odermatt A.
    Drug Metab Dispos; 2013 Sep; 41(9):1671-8. PubMed ID: 23804523
    [Abstract] [Full Text] [Related]

  • 2. Carbonyl reduction of triadimefon by human and rodent 11β-hydroxysteroid dehydrogenase 1.
    Meyer A, Vuorinen A, Zielinska AE, Da Cunha T, Strajhar P, Lavery GG, Schuster D, Odermatt A.
    Biochem Pharmacol; 2013 May 01; 85(9):1370-8. PubMed ID: 23419873
    [Abstract] [Full Text] [Related]

  • 3. Metabolism of bupropion by carbonyl reductases in liver and intestine.
    Connarn JN, Zhang X, Babiskin A, Sun D.
    Drug Metab Dispos; 2015 Jul 01; 43(7):1019-27. PubMed ID: 25904761
    [Abstract] [Full Text] [Related]

  • 4. Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11β-hydroxysteroid dehydrogenase 1.
    Odermatt A, Da Cunha T, Penno CA, Chandsawangbhuwana C, Reichert C, Wolf A, Dong M, Baker ME.
    Biochem J; 2011 Jun 15; 436(3):621-9. PubMed ID: 21453287
    [Abstract] [Full Text] [Related]

  • 5. Osteoblastic 11beta-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure.
    Cooper MS, Rabbitt EH, Goddard PE, Bartlett WA, Hewison M, Stewart PM.
    J Bone Miner Res; 2002 Jun 15; 17(6):979-86. PubMed ID: 12054173
    [Abstract] [Full Text] [Related]

  • 6. Carbonyl reduction of bupropion in human liver.
    Molnari JC, Myers AL.
    Xenobiotica; 2012 Jun 15; 42(6):550-61. PubMed ID: 22339467
    [Abstract] [Full Text] [Related]

  • 7. Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid.
    Penno CA, Morgan SA, Vuorinen A, Schuster D, Lavery GG, Odermatt A.
    J Lipid Res; 2013 Oct 15; 54(10):2874-83. PubMed ID: 23933573
    [Abstract] [Full Text] [Related]

  • 8. Deeper insight into the reducing biotransformation of bupropion in the human liver.
    Skarydova L, Tomanova R, Havlikova L, Stambergova H, Solich P, Wsol V.
    Drug Metab Pharmacokinet; 2014 Oct 15; 29(2):177-84. PubMed ID: 24088726
    [Abstract] [Full Text] [Related]

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  • 10. Comparative enzymology of 11beta-hydroxysteroid dehydrogenase type 1 from six species.
    Arampatzis S, Kadereit B, Schuster D, Balazs Z, Schweizer RA, Frey FJ, Langer T, Odermatt A.
    J Mol Endocrinol; 2005 Aug 15; 35(1):89-101. PubMed ID: 16087724
    [Abstract] [Full Text] [Related]

  • 11. Main metabolic pathways of TAK-802, a novel drug candidate for voiding dysfunction, in humans: the involvement of carbonyl reduction by 11β-hydroxysteroid dehydrogenase 1.
    Nishihara M, Takahashi J, Kondo T, Mouri K, Asahi S.
    Drug Res (Stuttg); 2014 Sep 15; 64(9):476-84. PubMed ID: 24357138
    [Abstract] [Full Text] [Related]

  • 12. Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1.
    Lavery GG, Zielinska AE, Gathercole LL, Hughes B, Semjonous N, Guest P, Saqib K, Sherlock M, Reynolds G, Morgan SA, Tomlinson JW, Walker EA, Rabbitt EH, Stewart PM.
    Endocrinology; 2012 Jul 15; 153(7):3236-48. PubMed ID: 22555437
    [Abstract] [Full Text] [Related]

  • 13. Development, validation and application of a comprehensive stereoselective LC/MS-MS assay for bupropion and oxidative, reductive, and glucuronide metabolites in human urine.
    Teitelbaum AM, Flaker AM, Kharasch ED.
    J Chromatogr B Analyt Technol Biomed Life Sci; 2016 Aug 01; 1027():239-53. PubMed ID: 27318149
    [Abstract] [Full Text] [Related]

  • 14. Green tea and one of its constituents, Epigallocatechine-3-gallate, are potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1.
    Hintzpeter J, Stapelfeld C, Loerz C, Martin HJ, Maser E.
    PLoS One; 2014 Aug 01; 9(1):e84468. PubMed ID: 24404164
    [Abstract] [Full Text] [Related]

  • 15. Bupropion metabolism by human placenta.
    Wang X, Abdelrahman DR, Zharikova OL, Patrikeeva SL, Hankins GD, Ahmed MS, Nanovskaya TN.
    Biochem Pharmacol; 2010 Jun 01; 79(11):1684-90. PubMed ID: 20109440
    [Abstract] [Full Text] [Related]

  • 16. Quantification of 11β-hydroxysteroid dehydrogenase 1 kinetics and pharmacodynamic effects of inhibitors in brain using mass spectrometry imaging and stable-isotope tracers in mice.
    Cobice DF, Livingstone DEW, McBride A, MacKay CL, Walker BR, Webster SP, Andrew R.
    Biochem Pharmacol; 2018 Feb 01; 148():88-99. PubMed ID: 29248595
    [Abstract] [Full Text] [Related]

  • 17. In vivo evaluation of 11beta-hydroxysteroid dehydrogenase activity in the rabbit eye.
    Anderson S, Carreiro S, Quenzer T, Gale D, Xiang C, Gukasyan H, Lafontaine J, Cheng H, Krauss A, Prasanna G.
    J Ocul Pharmacol Ther; 2009 Jun 01; 25(3):215-22. PubMed ID: 19456256
    [Abstract] [Full Text] [Related]

  • 18. Hexose-6-phosphate dehydrogenase modulates 11beta-hydroxysteroid dehydrogenase type 1-dependent metabolism of 7-keto- and 7beta-hydroxy-neurosteroids.
    Nashev LG, Chandsawangbhuwana C, Balazs Z, Atanasov AG, Dick B, Frey FJ, Baker ME, Odermatt A.
    PLoS One; 2007 Jun 27; 2(6):e561. PubMed ID: 17593962
    [Abstract] [Full Text] [Related]

  • 19. Resveratrol inhibits 11β-hydroxysteroid dehydrogenase type 1 activity in rat adipose microsomes.
    Tagawa N, Kubota S, Kato I, Kobayashi Y.
    J Endocrinol; 2013 Sep 27; 218(3):311-20. PubMed ID: 23814014
    [Abstract] [Full Text] [Related]

  • 20. 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) mediates insulin resistance through JNK activation in adipocytes.
    Peng K, Pan Y, Li J, Khan Z, Fan M, Yin H, Tong C, Zhao Y, Liang G, Zheng C.
    Sci Rep; 2016 Nov 14; 6():37160. PubMed ID: 27841334
    [Abstract] [Full Text] [Related]


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