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220 related items for PubMed ID: 23816435

  • 1. Hepatic glycogen cycling contributes to glucose lowering effects of the glucokinase activator LCZ960.
    Laurent D, Yerby B, Zhang B, Chen XH, Gounarides J, Zhang J, Gao J, Bebernitz G, Duttaroy A.
    Eur J Pharmacol; 2013 Sep 05; 715(1-3):89-95. PubMed ID: 23816435
    [Abstract] [Full Text] [Related]

  • 2. Fatty acid and amino acid modulation of glucose cycling in isolated rat hepatocytes.
    Gustafson LA, Neeft M, Reijngoud DJ, Kuipers F, Sauerwein HP, Romijn JA, Herling AW, Burger HJ, Meijer AJ.
    Biochem J; 2001 Sep 15; 358(Pt 3):665-71. PubMed ID: 11535127
    [Abstract] [Full Text] [Related]

  • 3. Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation. Relation to the insulin-mediated inhibition of hepatic glucose production.
    Rossetti L, Hu M.
    J Clin Invest; 1993 Dec 15; 92(6):2963-74. PubMed ID: 8254050
    [Abstract] [Full Text] [Related]

  • 4. Defect in glucokinase translocation in Zucker diabetic fatty rats.
    Fujimoto Y, Donahue EP, Shiota M.
    Am J Physiol Endocrinol Metab; 2004 Sep 15; 287(3):E414-23. PubMed ID: 15138155
    [Abstract] [Full Text] [Related]

  • 5. Glucose toxicity is responsible for the development of impaired regulation of endogenous glucose production and hepatic glucokinase in Zucker diabetic fatty rats.
    Fujimoto Y, Torres TP, Donahue EP, Shiota M.
    Diabetes; 2006 Sep 15; 55(9):2479-90. PubMed ID: 16936196
    [Abstract] [Full Text] [Related]

  • 6. Chronic glucokinase activation reduces glycaemia and improves glucose tolerance in high-fat diet fed mice.
    Winzell MS, Coghlan M, Leighton B, Frangioudakis G, Smith DM, Storlien LH, Ahrén B.
    Eur J Pharmacol; 2011 Aug 01; 663(1-3):80-6. PubMed ID: 21586282
    [Abstract] [Full Text] [Related]

  • 7. Evidence from transgenic mice that glucokinase is rate limiting for glucose utilization in the liver.
    Ferre T, Riu E, Bosch F, Valera A.
    FASEB J; 1996 Aug 01; 10(10):1213-8. PubMed ID: 8751724
    [Abstract] [Full Text] [Related]

  • 8. Hepatic ChREBP orchestrates intrahepatic carbohydrate metabolism to limit hepatic glucose 6-phosphate and glycogen accumulation in a mouse model for acute Glycogen Storage Disease type Ib.
    Krishnamurthy KA, Rutten MGS, Hoogerland JA, van Dijk TH, Bos T, Koehorst M, de Vries MP, Kloosterhuis NJ, Havinga H, Schomakers BV, van Weeghel M, Wolters JC, Bakker BM, Oosterveer MH.
    Mol Metab; 2024 Jan 01; 79():101838. PubMed ID: 37995884
    [Abstract] [Full Text] [Related]

  • 9. Metabolic control analysis of hepatic glycogen synthesis in vivo.
    Nozaki Y, Petersen MC, Zhang D, Vatner DF, Perry RJ, Abulizi A, Haedersdal S, Zhang XM, Butrico GM, Samuel VT, Mason GF, Cline GW, Petersen KF, Rothman DL, Shulman GI.
    Proc Natl Acad Sci U S A; 2020 Apr 07; 117(14):8166-8176. PubMed ID: 32188779
    [Abstract] [Full Text] [Related]

  • 10. Allosteric activators of glucokinase: potential role in diabetes therapy.
    Grimsby J, Sarabu R, Corbett WL, Haynes NE, Bizzarro FT, Coffey JW, Guertin KR, Hilliard DW, Kester RF, Mahaney PE, Marcus L, Qi L, Spence CL, Tengi J, Magnuson MA, Chu CA, Dvorozniak MT, Matschinsky FM, Grippo JF.
    Science; 2003 Jul 18; 301(5631):370-3. PubMed ID: 12869762
    [Abstract] [Full Text] [Related]

  • 11. Lithium's effects on rat liver glucose metabolism in vivo.
    Rodriguez-Gil JE, Fernández-Novell JM, Barberá A, Guinovart JJ.
    Arch Biochem Biophys; 2000 Mar 15; 375(2):377-84. PubMed ID: 10700396
    [Abstract] [Full Text] [Related]

  • 12. Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation. Evidence against feedback inhibition of glucokinase.
    Aiston S, Trinh KY, Lange AJ, Newgard CB, Agius L.
    J Biol Chem; 1999 Aug 27; 274(35):24559-66. PubMed ID: 10455119
    [Abstract] [Full Text] [Related]

  • 13. Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis.
    von Wilamowitz-Moellendorff A, Hunter RW, García-Rocha M, Kang L, López-Soldado I, Lantier L, Patel K, Peggie MW, Martínez-Pons C, Voss M, Calbó J, Cohen PT, Wasserman DH, Guinovart JJ, Sakamoto K.
    Diabetes; 2013 Dec 27; 62(12):4070-82. PubMed ID: 23990365
    [Abstract] [Full Text] [Related]

  • 14. The role of glucose 6-phosphate in mediating the effects of glucokinase overexpression on hepatic glucose metabolism.
    Härndahl L, Schmoll D, Herling AW, Agius L.
    FEBS J; 2006 Jan 27; 273(2):336-46. PubMed ID: 16403021
    [Abstract] [Full Text] [Related]

  • 15. Diets enriched in sucrose or fat increase gluconeogenesis and G-6-Pase but not basal glucose production in rats.
    Commerford SR, Ferniza JB, Bizeau ME, Thresher JS, Willis WT, Pagliassotti MJ.
    Am J Physiol Endocrinol Metab; 2002 Sep 27; 283(3):E545-55. PubMed ID: 12169448
    [Abstract] [Full Text] [Related]

  • 16. Treatment with exendin-4 improves the antidiabetic efficacy and reverses hepatic steatosis in glucokinase activator treated db/db mice.
    Dhanesha N, Joharapurkar A, Shah G, Kshirsagar S, Patel V, Patel K, Bahekar R, Jain M.
    Eur J Pharmacol; 2013 Aug 15; 714(1-3):188-92. PubMed ID: 23810686
    [Abstract] [Full Text] [Related]

  • 17. Glucokinase activator PSN-GK1 displays enhanced antihyperglycaemic and insulinotropic actions.
    Fyfe MC, White JR, Taylor A, Chatfield R, Wargent E, Printz RL, Sulpice T, McCormack JG, Procter MJ, Reynet C, Widdowson PS, Wong-Kai-In P.
    Diabetologia; 2007 Jun 15; 50(6):1277-87. PubMed ID: 17415548
    [Abstract] [Full Text] [Related]

  • 18. Increased potency and efficacy of combined phosphorylase inactivation and glucokinase activation in control of hepatocyte glycogen metabolism.
    Hampson LJ, Agius L.
    Diabetes; 2005 Mar 15; 54(3):617-23. PubMed ID: 15734835
    [Abstract] [Full Text] [Related]

  • 19. Discovery of liver-directed glucokinase activator having anti-hyperglycemic effect without hypoglycemia.
    Deshpande AM, Bhuniya D, De S, Dave B, Vyavahare VP, Kurhade SH, Kandalkar SR, Naik KP, Kobal BS, Kaduskar RD, Basu S, Jain V, Patil P, Chaturvedi Joshi S, Bhat G, Raje AA, Reddy S, Gundu J, Madgula V, Tambe S, Shitole P, Umrani D, Chugh A, Palle VP, Mookhtiar KA.
    Eur J Med Chem; 2017 Jun 16; 133():268-286. PubMed ID: 28390958
    [Abstract] [Full Text] [Related]

  • 20. Glucose 6-phosphate regulates hepatic glycogenolysis through inactivation of phosphorylase.
    Aiston S, Andersen B, Agius L.
    Diabetes; 2003 Jun 16; 52(6):1333-9. PubMed ID: 12765941
    [Abstract] [Full Text] [Related]

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