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Journal Abstract Search

220 related items for PubMed ID: 23816435

  • 21. The hepatoselective glucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats.
    Erion DM, Lapworth A, Amor PA, Bai G, Vera NB, Clark RW, Yan Q, Zhu Y, Ross TT, Purkal J, Gorgoglione M, Zhang G, Bonato V, Baker L, Barucci N, D'Aquila T, Robertson A, Aiello RJ, Yan J, Trimmer J, Rolph TP, Pfefferkorn JA.
    PLoS One; 2014; 9(5):e97139. PubMed ID: 24858947
    [Abstract] [Full Text] [Related]

  • 22. An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.
    Futamura M, Hosaka H, Kadotani A, Shimazaki H, Sasaki K, Ohyama S, Nishimura T, Eiki J, Nagata Y.
    J Biol Chem; 2006 Dec 08; 281(49):37668-74. PubMed ID: 17028192
    [Abstract] [Full Text] [Related]

  • 23. Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes plasma glucose in zucker diabetic fatty rats.
    Torres TP, Catlin RL, Chan R, Fujimoto Y, Sasaki N, Printz RL, Newgard CB, Shiota M.
    Diabetes; 2009 Jan 08; 58(1):78-86. PubMed ID: 18952838
    [Abstract] [Full Text] [Related]

  • 24. Adenovirus-mediated expression of glucokinase in the liver as an adjuvant treatment for type 1 diabetes.
    Morral N, McEvoy R, Dong H, Meseck M, Altomonte J, Thung S, Woo SL.
    Hum Gene Ther; 2002 Sep 01; 13(13):1561-70. PubMed ID: 12228011
    [Abstract] [Full Text] [Related]

  • 25. Glucose 6-phosphate produced by gluconeogenesis and by glucokinase is equally effective in activating hepatic glycogen synthase.
    Gomis RR, Favre C, García-Rocha M, Fernández-Novell JM, Ferrer JC, Guinovart JJ.
    J Biol Chem; 2003 Mar 14; 278(11):9740-6. PubMed ID: 12519761
    [Abstract] [Full Text] [Related]

  • 26. Importance of substrate changes in the decrease of hepatic glucose cycling during insulin infusion and declining glycemia in the depancreatized dog.
    Shi ZQ, Giacca A, Fisher S, Vidal H, van de Werve G, Vranic M.
    Diabetes; 1994 Nov 14; 43(11):1284-90. PubMed ID: 7926301
    [Abstract] [Full Text] [Related]

  • 27. Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites.
    Lam TK, van de Werve G, Giacca A.
    Am J Physiol Endocrinol Metab; 2003 Feb 14; 284(2):E281-90. PubMed ID: 12531742
    [Abstract] [Full Text] [Related]

  • 28. Stimulation of hepatocyte glucose metabolism by novel small molecule glucokinase activators.
    Brocklehurst KJ, Payne VA, Davies RA, Carroll D, Vertigan HL, Wightman HJ, Aiston S, Waddell ID, Leighton B, Coghlan MP, Agius L.
    Diabetes; 2004 Mar 14; 53(3):535-41. PubMed ID: 14988235
    [Abstract] [Full Text] [Related]

  • 29. Glucokinase and molecular aspects of liver glycogen metabolism.
    Agius L.
    Biochem J; 2008 Aug 15; 414(1):1-18. PubMed ID: 18651836
    [Abstract] [Full Text] [Related]

  • 30. Exendin-4 ameliorates diabetic symptoms through activation of glucokinase.
    Dhanesha N, Joharapurkar A, Shah G, Dhote V, Kshirsagar S, Bahekar R, Jain M.
    J Diabetes; 2012 Dec 15; 4(4):369-77. PubMed ID: 22356440
    [Abstract] [Full Text] [Related]

  • 31. A novel glucokinase activator modulates pancreatic islet and hepatocyte function.
    Efanov AM, Barrett DG, Brenner MB, Briggs SL, Delaunois A, Durbin JD, Giese U, Guo H, Radloff M, Gil GS, Sewing S, Wang Y, Weichert A, Zaliani A, Gromada J.
    Endocrinology; 2005 Sep 15; 146(9):3696-701. PubMed ID: 15919746
    [Abstract] [Full Text] [Related]

  • 32. Stimulating effects of low-dose fructose on insulin-stimulated hepatic glycogen synthesis in humans.
    Petersen KF, Laurent D, Yu C, Cline GW, Shulman GI.
    Diabetes; 2001 Jun 15; 50(6):1263-8. PubMed ID: 11375325
    [Abstract] [Full Text] [Related]

  • 33. A defect in glucose-induced dissociation of glucokinase from the regulatory protein in Zucker diabetic fatty rats in the early stage of diabetes.
    Shin JS, Torres TP, Catlin RL, Donahue EP, Shiota M.
    Am J Physiol Regul Integr Comp Physiol; 2007 Apr 15; 292(4):R1381-90. PubMed ID: 17204595
    [Abstract] [Full Text] [Related]

  • 34. Two birds with one stone: novel glucokinase activator stimulates glucose-induced pancreatic insulin secretion and augments hepatic glucose metabolism.
    Al-Hasani H, Tschöp MH, Cushman SW.
    Mol Interv; 2003 Oct 15; 3(7):367-70. PubMed ID: 14993457
    [Abstract] [Full Text] [Related]

  • 35. Role of glucose-6 phosphatase, glucokinase, and glucose-6 phosphate in liver insulin resistance and its correction by metformin.
    Minassian C, Tarpin S, Mithieux G.
    Biochem Pharmacol; 1998 Apr 15; 55(8):1213-9. PubMed ID: 9719475
    [Abstract] [Full Text] [Related]

  • 36. Chronic intraperitoneal insulin delivery, as compared with subcutaneous delivery, improves hepatic glucose metabolism in streptozotocin diabetic rats.
    Mason TM, Gupta N, Goh T, El-Bahrani B, Zannis J, van de Werve G, Giacca A.
    Metabolism; 2000 Nov 15; 49(11):1411-6. PubMed ID: 11092503
    [Abstract] [Full Text] [Related]

  • 37. Opposite effects of a glucokinase activator and metformin on glucose-regulated gene expression in hepatocytes.
    Al-Oanzi ZH, Fountana S, Moonira T, Tudhope SJ, Petrie JL, Alshawi A, Patman G, Arden C, Reeves HL, Agius L.
    Diabetes Obes Metab; 2017 Aug 15; 19(8):1078-1087. PubMed ID: 28206714
    [Abstract] [Full Text] [Related]

  • 38. The physiological role of glucokinase binding and translocation in hepatocytes.
    Agius L.
    Adv Enzyme Regul; 1998 Aug 15; 38():303-31. PubMed ID: 9762360
    [Abstract] [Full Text] [Related]

  • 39. Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes.
    Rossetti L, Giaccari A, Barzilai N, Howard K, Sebel G, Hu M.
    J Clin Invest; 1993 Sep 15; 92(3):1126-34. PubMed ID: 8397219
    [Abstract] [Full Text] [Related]

  • 40. Medicinal chemistry approaches for glucokinase activation to treat type 2 diabetes.
    Pal M.
    Curr Med Chem; 2009 Sep 15; 16(29):3858-74. PubMed ID: 19747136
    [Abstract] [Full Text] [Related]

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