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Journal Abstract Search


211 related items for PubMed ID: 23821261

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  • 3. Specific inhibitors of HCV polymerase identified using an NS5B with lower affinity for template/primer substrate.
    McKercher G, Beaulieu PL, Lamarre D, LaPlante S, Lefebvre S, Pellerin C, Thauvette L, Kukolj G.
    Nucleic Acids Res; 2004; 32(2):422-31. PubMed ID: 14739234
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  • 4. A homogeneous, solid-phase assay for hepatitis C virus RNA-dependent RNA polymerase.
    Wang YK, Rigat KL, Roberts SB, Gao M.
    Anal Biochem; 2006 Dec 01; 359(1):106-11. PubMed ID: 17054898
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  • 5. Selection of 3'-template bases and initiating nucleotides by hepatitis C virus NS5B RNA-dependent RNA polymerase.
    Shim JH, Larson G, Wu JZ, Hong Z.
    J Virol; 2002 Jul 01; 76(14):7030-9. PubMed ID: 12072503
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  • 6. De novo initiation of RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase.
    Zhong W, Uss AS, Ferrari E, Lau JY, Hong Z.
    J Virol; 2000 Feb 01; 74(4):2017-22. PubMed ID: 10644375
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  • 7. Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase.
    Nikonov A, Juronen E, Ustav M.
    J Biol Chem; 2008 Aug 29; 283(35):24089-102. PubMed ID: 18574240
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  • 8. De novo RNA synthesis catalyzed by HCV RNA-dependent RNA polymerase.
    Sun XL, Johnson RB, Hockman MA, Wang QM.
    Biochem Biophys Res Commun; 2000 Feb 24; 268(3):798-803. PubMed ID: 10679285
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  • 9. Recent advances on the synthesis of hepatitis C virus NS5B RNA-dependent RNA-polymerase inhibitors.
    Zhao C, Wang Y, Ma S.
    Eur J Med Chem; 2015 Sep 18; 102():188-214. PubMed ID: 26276434
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  • 10. De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus.
    Luo G, Hamatake RK, Mathis DM, Racela J, Rigat KL, Lemm J, Colonno RJ.
    J Virol; 2000 Jan 18; 74(2):851-63. PubMed ID: 10623748
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  • 11. Evidence for Internal Initiation of RNA Synthesis by the Hepatitis C Virus RNA-Dependent RNA Polymerase NS5B In Cellulo.
    Schult P, Nattermann M, Lauber C, Seitz S, Lohmann V.
    J Virol; 2019 Oct 01; 93(19):. PubMed ID: 31315989
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  • 12. Template requirement and initiation site selection by hepatitis C virus polymerase on a minimal viral RNA template.
    Oh JW, Sheu GT, Lai MM.
    J Biol Chem; 2000 Jun 09; 275(23):17710-7. PubMed ID: 10749880
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  • 13. Biochemical properties of full-length hepatitis C virus RNA-dependent RNA polymerase expressed in insect cells.
    Choi HB, Kim YG, Oh JW.
    Exp Mol Med; 2003 Dec 31; 35(6):475-85. PubMed ID: 14749524
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  • 14. Ligand-induced changes in hepatitis C virus NS5B polymerase structure.
    Rigat K, Wang Y, Hudyma TW, Ding M, Zheng X, Gentles RG, Beno BR, Gao M, Roberts SB.
    Antiviral Res; 2010 Nov 31; 88(2):197-206. PubMed ID: 20813137
    [Abstract] [Full Text] [Related]

  • 15. Enzymatic characterization of the full-length and C-terminally truncated hepatitis C virus RNA polymerases: function of the last 21 amino acids of the C terminus in template binding and RNA synthesis.
    Vo NV, Tuler JR, Lai MM.
    Biochemistry; 2004 Aug 17; 43(32):10579-91. PubMed ID: 15301555
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  • 16. Template requirements for de novo RNA synthesis by hepatitis C virus nonstructural protein 5B polymerase on the viral X RNA.
    Kim M, Kim H, Cho SP, Min MK.
    J Virol; 2002 Jul 17; 76(14):6944-56. PubMed ID: 12072495
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  • 17. The novel nucleoside analog R1479 (4'-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture.
    Klumpp K, Lévêque V, Le Pogam S, Ma H, Jiang WR, Kang H, Granycome C, Singer M, Laxton C, Hang JQ, Sarma K, Smith DB, Heindl D, Hobbs CJ, Merrett JH, Symons J, Cammack N, Martin JA, Devos R, Nájera I.
    J Biol Chem; 2006 Feb 17; 281(7):3793-9. PubMed ID: 16316989
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  • 18. Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors.
    Jin G, Lee S, Choi M, Son S, Kim GW, Oh JW, Lee C, Lee K.
    Eur J Med Chem; 2014 Mar 21; 75():413-25. PubMed ID: 24561671
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  • 19. Phosphorylation of hepatitis C virus RNA polymerases ser29 and ser42 by protein kinase C-related kinase 2 regulates viral RNA replication.
    Han SH, Kim SJ, Kim EJ, Kim TE, Moon JS, Kim GW, Lee SH, Cho K, Yoo JS, Son WS, Rhee JK, Han SH, Oh JW.
    J Virol; 2014 Oct 21; 88(19):11240-52. PubMed ID: 25031343
    [Abstract] [Full Text] [Related]

  • 20. A relaxed discrimination of 2'-O-methyl-GTP relative to GTP between de novo and Elongative RNA synthesis by the hepatitis C RNA-dependent RNA polymerase NS5B.
    Dutartre H, Boretto J, Guillemot JC, Canard B.
    J Biol Chem; 2005 Feb 25; 280(8):6359-68. PubMed ID: 15561709
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