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217 related items for PubMed ID: 23821767

  • 1. Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model.
    Hahm ER, Lee J, Kim SH, Sehrawat A, Arlotti JA, Shiva SS, Bhargava R, Singh SV.
    J Natl Cancer Inst; 2013 Aug 07; 105(15):1111-22. PubMed ID: 23821767
    [Abstract] [Full Text] [Related]

  • 2. Disease Subtype-Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical Withaferin A.
    Samanta SK, Sehrawat A, Kim SH, Hahm ER, Shuai Y, Roy R, Pore SK, Singh KB, Christner SM, Beumer JH, Davidson NE, Singh SV.
    J Natl Cancer Inst; 2017 Jun 07; 109(6):. PubMed ID: 28040797
    [Abstract] [Full Text] [Related]

  • 3. Biomarkers of phenethyl isothiocyanate-mediated mammary cancer chemoprevention in a clinically relevant mouse model.
    Singh SV, Kim SH, Sehrawat A, Arlotti JA, Hahm ER, Sakao K, Beumer JH, Jankowitz RC, Chandra-Kuntal K, Lee J, Powolny AA, Dhir R.
    J Natl Cancer Inst; 2012 Aug 22; 104(16):1228-39. PubMed ID: 22859850
    [Abstract] [Full Text] [Related]

  • 4. Mammary cancer chemoprevention by withaferin A is accompanied by in vivo suppression of self-renewal of cancer stem cells.
    Kim SH, Singh SV.
    Cancer Prev Res (Phila); 2014 Jul 22; 7(7):738-47. PubMed ID: 24824039
    [Abstract] [Full Text] [Related]

  • 5. Peptidyl-prolyl cis/trans isomerase Pin1 regulates withaferin A-mediated cell cycle arrest in human breast cancer cells.
    Samanta SK, Lee J, Hahm ER, Singh SV.
    Mol Carcinog; 2018 Jul 22; 57(7):936-946. PubMed ID: 29603395
    [Abstract] [Full Text] [Related]

  • 6. Prevention of mammary carcinogenesis in MMTV-neu mice by cruciferous vegetable constituent benzyl isothiocyanate.
    Warin R, Chambers WH, Potter DM, Singh SV.
    Cancer Res; 2009 Dec 15; 69(24):9473-80. PubMed ID: 19934325
    [Abstract] [Full Text] [Related]

  • 7. Autophagy fails to alter withaferin A-mediated lethality in human breast cancer cells.
    Hahm ER, Singh SV.
    Curr Cancer Drug Targets; 2013 Jul 15; 13(6):640-50. PubMed ID: 23607597
    [Abstract] [Full Text] [Related]

  • 8. Withaferin A inhibits expression of ataxia telangiectasia and Rad3-related kinase and enhances sensitivity of human breast cancer cells to cisplatin.
    Hahm ER, Lee J, Abella T, Singh SV.
    Mol Carcinog; 2019 Nov 15; 58(11):2139-2148. PubMed ID: 31441116
    [Abstract] [Full Text] [Related]

  • 9. Withaferin A Inhibits Fatty Acid Synthesis in Rat Mammary Tumors.
    Singh KB, Hahm ER, Kim SH, Singh SV.
    Cancer Prev Res (Phila); 2023 Jan 04; 16(1):5-16. PubMed ID: 36251722
    [Abstract] [Full Text] [Related]

  • 10. Long-term exposure to elevated levels of circulating TIMP-1 but not mammary TIMP-1 suppresses growth of mammary carcinomas in transgenic mice.
    Yamazaki M, Akahane T, Buck T, Yoshiji H, Gomez DE, Schoeffner DJ, Okajima E, Harris SR, Bunce OR, Thorgeirsson SS, Thorgeirsson UP.
    Carcinogenesis; 2004 Sep 04; 25(9):1735-46. PubMed ID: 15166086
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera's key metabolite withaferin A.
    Grover A, Shandilya A, Punetha A, Bisaria VS, Sundar D.
    BMC Genomics; 2010 Dec 02; 11 Suppl 4(Suppl 4):S25. PubMed ID: 21143809
    [Abstract] [Full Text] [Related]

  • 12. RNA-seq reveals novel cancer-selective and disease subtype-independent mechanistic targets of withaferin A in human breast cancer cells.
    Hahm ER, Kim SH, Singh KB, Singh SV.
    Mol Carcinog; 2021 Jan 02; 60(1):3-14. PubMed ID: 33150660
    [Abstract] [Full Text] [Related]

  • 13. Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.
    Hahm ER, Moura MB, Kelley EE, Van Houten B, Shiva S, Singh SV.
    PLoS One; 2011 Jan 02; 6(8):e23354. PubMed ID: 21853114
    [Abstract] [Full Text] [Related]

  • 14. Chemopreventative potential of the cruciferous vegetable constituent phenethyl isothiocyanate in a mouse model of prostate cancer.
    Powolny AA, Bommareddy A, Hahm ER, Normolle DP, Beumer JH, Nelson JB, Singh SV.
    J Natl Cancer Inst; 2011 Apr 06; 103(7):571-84. PubMed ID: 21330634
    [Abstract] [Full Text] [Related]

  • 15. Down-regulation of estrogen receptor-alpha and rearranged during transfection tyrosine kinase is associated with withaferin a-induced apoptosis in MCF-7 breast cancer cells.
    Zhang X, Mukerji R, Samadi AK, Cohen MS.
    BMC Complement Altern Med; 2011 Oct 06; 11():84. PubMed ID: 21978374
    [Abstract] [Full Text] [Related]

  • 16. Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells.
    Hahm ER, Lee J, Singh SV.
    Mol Carcinog; 2014 Nov 06; 53(11):907-16. PubMed ID: 24019090
    [Abstract] [Full Text] [Related]

  • 17. The Role of Forkhead Box Q1 Transcription Factor in Anticancer Effects of Withaferin A in Breast Cancer.
    Kim SH, Singh KB, Hahm ER, Singh SV.
    Cancer Prev Res (Phila); 2021 Apr 06; 14(4):421-432. PubMed ID: 33509807
    [Abstract] [Full Text] [Related]

  • 18. Short-term early exposure to lapatinib confers lifelong protection from mammary tumor development in MMTV-erbB-2 transgenic mice.
    Ma Z, Parris AB, Xiao Z, Howard EW, Kosanke SD, Feng X, Yang X.
    J Exp Clin Cancer Res; 2017 Jan 06; 36(1):6. PubMed ID: 28061785
    [Abstract] [Full Text] [Related]

  • 19. Withaferin A-mediated apoptosis in breast cancer cells is associated with alterations in mitochondrial dynamics.
    Sehrawat A, Samanta SK, Hahm ER, St Croix C, Watkins S, Singh SV.
    Mitochondrion; 2019 Jul 06; 47():282-293. PubMed ID: 30685490
    [Abstract] [Full Text] [Related]

  • 20. Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo.
    Stan SD, Hahm ER, Warin R, Singh SV.
    Cancer Res; 2008 Sep 15; 68(18):7661-9. PubMed ID: 18794155
    [Abstract] [Full Text] [Related]

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