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Journal Abstract Search
317 related items for PubMed ID: 23859207
1. Small-molecule inhibition of bacterial two-component systems to combat antibiotic resistance and virulence. Worthington RJ, Blackledge MS, Melander C. Future Med Chem; 2013 Jul; 5(11):1265-84. PubMed ID: 23859207 [Abstract] [Full Text] [Related]
2. Two-component signal transduction as potential drug targets in pathogenic bacteria. Gotoh Y, Eguchi Y, Watanabe T, Okamoto S, Doi A, Utsumi R. Curr Opin Microbiol; 2010 Apr; 13(2):232-9. PubMed ID: 20138000 [Abstract] [Full Text] [Related]
3. Evaluation of small molecule kinase inhibitors as novel antimicrobial and antibiofilm agents. King A, Blackledge MS. Chem Biol Drug Des; 2021 Dec; 98(6):1038-1064. PubMed ID: 34581492 [Abstract] [Full Text] [Related]
4. Paradigm shift in discovering next-generation anti-infective agents: targeting quorum sensing, c-di-GMP signaling and biofilm formation in bacteria with small molecules. Sintim HO, Smith JA, Wang J, Nakayama S, Yan L. Future Med Chem; 2010 Jun; 2(6):1005-35. PubMed ID: 21426116 [Abstract] [Full Text] [Related]
5. Anti-virulence Strategies to Target Bacterial Infections. Mühlen S, Dersch P. Curr Top Microbiol Immunol; 2016 Jun; 398():147-183. PubMed ID: 26942418 [Abstract] [Full Text] [Related]
6. [Two-component signal transduction as attractive drug targets in pathogenic bacteria]. Utsumi R, Igarashi M. Yakugaku Zasshi; 2012 Jun; 132(1):51-8. PubMed ID: 22214580 [Abstract] [Full Text] [Related]
7. Inhibitors targeting two-component signal transduction. Watanabe T, Okada A, Gotoh Y, Utsumi R. Adv Exp Med Biol; 2008 Jun; 631():229-36. PubMed ID: 18792693 [Abstract] [Full Text] [Related]
8. Small molecule downregulation of PmrAB reverses lipid A modification and breaks colistin resistance. Harris TL, Worthington RJ, Hittle LE, Zurawski DV, Ernst RK, Melander C. ACS Chem Biol; 2014 Jan 17; 9(1):122-7. PubMed ID: 24131198 [Abstract] [Full Text] [Related]
9. Virulence-targeted Antibacterials: Concept, Promise, and Susceptibility to Resistance Mechanisms. Ruer S, Pinotsis N, Steadman D, Waksman G, Remaut H. Chem Biol Drug Des; 2015 Oct 17; 86(4):379-99. PubMed ID: 25589217 [Abstract] [Full Text] [Related]
10. Global priority pathogens: virulence, antimicrobial resistance and prospective treatment options. M Campos JC, Antunes LC, Ferreira RB. Future Microbiol; 2020 May 17; 15():649-677. PubMed ID: 32495702 [Abstract] [Full Text] [Related]
11. Bacterial histidine kinases as novel antibacterial drug targets. Bem AE, Velikova N, Pellicer MT, Baarlen Pv, Marina A, Wells JM. ACS Chem Biol; 2015 Jan 16; 10(1):213-24. PubMed ID: 25436989 [Abstract] [Full Text] [Related]
12. Traffic jam at the bacterial sec translocase: targeting the SecA nanomotor by small-molecule inhibitors. Segers K, Anné J. Chem Biol; 2011 Jun 24; 18(6):685-98. PubMed ID: 21700205 [Abstract] [Full Text] [Related]
13. Agents that inhibit bacterial biofilm formation. Rabin N, Zheng Y, Opoku-Temeng C, Du Y, Bonsu E, Sintim HO. Future Med Chem; 2015 Jun 24; 7(5):647-71. PubMed ID: 25921403 [Abstract] [Full Text] [Related]
14. The use of quorum-sensing blockers as therapeutic agents for the control of biofilm-associated infections. Rice SA, McDougald D, Kumar N, Kjelleberg S. Curr Opin Investig Drugs; 2005 Feb 24; 6(2):178-84. PubMed ID: 15751741 [Abstract] [Full Text] [Related]
15. Structure-based discovery of inhibitors of the YycG histidine kinase: new chemical leads to combat Staphylococcus epidermidis infections. Qin Z, Zhang J, Xu B, Chen L, Wu Y, Yang X, Shen X, Molin S, Danchin A, Jiang H, Qu D. BMC Microbiol; 2006 Nov 10; 6():96. PubMed ID: 17094812 [Abstract] [Full Text] [Related]
16. The Small Molecule DAM Inhibitor, Pyrimidinedione, Disrupts Streptococcus pneumoniae Biofilm Growth In Vitro. Yadav MK, Go YY, Chae SW, Song JJ. PLoS One; 2015 Nov 10; 10(10):e0139238. PubMed ID: 26431532 [Abstract] [Full Text] [Related]
17. Small Molecules That Sabotage Bacterial Virulence. Johnson BK, Abramovitch RB. Trends Pharmacol Sci; 2017 Apr 10; 38(4):339-362. PubMed ID: 28209403 [Abstract] [Full Text] [Related]
18. Bisphosphocins: novel antimicrobials for enhanced killing of drug-resistant and biofilm-forming bacteria. Wong JP, DiTullio P, Parkinson S. Future Microbiol; 2015 Apr 10; 10(11):1751-8. PubMed ID: 26597426 [Abstract] [Full Text] [Related]
19. Targeting Two-Component Systems Uncovers a Small-Molecule Inhibitor of Salmonella Virulence. Tsai CN, MacNair CR, Cao MPT, Perry JN, Magolan J, Brown ED, Coombes BK. Cell Chem Biol; 2020 Jul 16; 27(7):793-805.e7. PubMed ID: 32413287 [Abstract] [Full Text] [Related]