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Journal Abstract Search

139 related items for PubMed ID: 2386547

  • 1. Toxication of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and analogs by monoamine oxidase. A structure-reactivity relationship study.
    Maret G, el Tayar N, Carrupt PA, Testa B, Jenner P, Baird M.
    Biochem Pharmacol; 1990 Aug 15; 40(4):783-92. PubMed ID: 2386547
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  • 2. Quantitative structure-metabolism relationship analyses of MAO-mediated toxication of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and analogues.
    Altomare C, Carrupt PA, Gaillard P, el Tayar N, Testa B, Carotti A.
    Chem Res Toxicol; 1992 Aug 15; 5(3):366-75. PubMed ID: 1504260
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  • 3. Interaction of flexible analogs of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of N-methyl-4-phenylpyridinium with highly purified monoamine oxidase A and B.
    Krueger MJ, Efange SM, Michelson RH, Singer TP.
    Biochemistry; 1992 Jun 23; 31(24):5611-5. PubMed ID: 1610807
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  • 4. Molecular determinants in the bioactivation of the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
    Efange SM, Boudreau RJ.
    J Comput Aided Mol Des; 1991 Oct 23; 5(5):405-17. PubMed ID: 1685185
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  • 5. Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. I. Evaluation of the biological activity of MPTP analogs.
    Youngster SK, Sonsalla PK, Sieber BA, Heikkila RE.
    J Pharmacol Exp Ther; 1989 Jun 23; 249(3):820-8. PubMed ID: 2786564
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  • 7. Oxidation of analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by monoamine oxidases A and B and the inhibition of monoamine oxidases by the oxidation products.
    Youngster SK, McKeown KA, Jin YZ, Ramsay RR, Heikkila RE, Singer TP.
    J Neurochem; 1989 Dec 23; 53(6):1837-42. PubMed ID: 2809594
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  • 9. Development of fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs with potent nigrostriatal toxicity for potential use in positron emission tomography studies.
    Harik SI, Riachi NJ, Hritz MA, Berridge MS, Sayre LM.
    J Pharmacol Exp Ther; 1993 Aug 23; 266(2):790-5. PubMed ID: 8355208
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  • 10. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine- and 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells: role of monoamine oxidase A.
    Basma AN, Heikkila RE, Nicklas WJ, Giovanni A, Geller HM.
    J Neurochem; 1990 Sep 23; 55(3):870-7. PubMed ID: 2384758
    [Abstract] [Full Text] [Related]

  • 11. Characterization of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) binding sites in C57BL/6 mouse brain: mutual effects of monoamine oxidase inhibitors and sigma ligands on MPTP and sigma binding sites.
    Itzhak Y, Mash D, Zhang SH, Stein I.
    Mol Pharmacol; 1991 Mar 23; 39(3):385-93. PubMed ID: 1848660
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  • 15. Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. II. Evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of MPTP analogs.
    Youngster SK, Nicklas WJ, Heikkila RE.
    J Pharmacol Exp Ther; 1989 Jun 23; 249(3):829-35. PubMed ID: 2786565
    [Abstract] [Full Text] [Related]

  • 16. Studies on the monoamine oxidase (MAO)-catalyzed oxidation of phenyl-substituted 1-methyl-4-phenoxy-1,2,3,6-tetrahydropyridine derivatives: factors contributing to MAO-A and MAO-B selectivity.
    Wang YX, Castagnoli N.
    J Med Chem; 1995 May 26; 38(11):1904-10. PubMed ID: 7783122
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  • 17. Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO).
    Herraiz T, Arán VJ, Guillén H.
    Free Radic Res; 2009 Oct 26; 43(10):975-84. PubMed ID: 19669997
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  • 18. Biotransformation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in primary cultures of mouse astrocytes.
    Di Monte DA, Wu EY, Irwin I, Delanney LE, Langston JW.
    J Pharmacol Exp Ther; 1991 Aug 26; 258(2):594-600. PubMed ID: 1907660
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  • 19. Molecular size and flexibility as determinants of selectivity in the oxidation of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs by monoamine oxidase A and B.
    Efange SM, Michelson RH, Tan AK, Krueger MJ, Singer TP.
    J Med Chem; 1993 Apr 30; 36(9):1278-83. PubMed ID: 8487265
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  • 20. Selegiline and the prophylaxis of Parkinson's disease.
    Sandler M, Willoughby J, Glover V, Gibb C.
    J Neural Transm Suppl; 1987 Apr 30; 25():35-43. PubMed ID: 3123604
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