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Journal Abstract Search

303 related items for PubMed ID: 23879463

  • 1. A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L.
    Anglin JL, Song Y.
    J Med Chem; 2013 Nov 27; 56(22):8972-83. PubMed ID: 23879463
    [Abstract] [Full Text] [Related]

  • 2. Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia.
    Feng Z, Yao Y, Zhou C, Chen F, Wu F, Wei L, Liu W, Dong S, Redell M, Mo Q, Song Y.
    J Hematol Oncol; 2016 Mar 12; 9():24. PubMed ID: 26970896
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and structure-activity relationship investigation of adenosine-containing inhibitors of histone methyltransferase DOT1L.
    Anglin JL, Deng L, Yao Y, Cai G, Liu Z, Jiang H, Cheng G, Chen P, Dong S, Song Y.
    J Med Chem; 2012 Sep 27; 55(18):8066-74. PubMed ID: 22924785
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  • 5. DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy.
    Liu W, Deng L, Song Y, Redell M.
    PLoS One; 2014 Sep 27; 9(5):e98270. PubMed ID: 24858818
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  • 7. Targeting the histone H3 lysine 79 methyltransferase DOT1L in MLL-rearranged leukemias.
    Yi Y, Ge S.
    J Hematol Oncol; 2022 Mar 24; 15(1):35. PubMed ID: 35331314
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  • 9. Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.
    Daigle SR, Olhava EJ, Therkelsen CA, Majer CR, Sneeringer CJ, Song J, Johnston LD, Scott MP, Smith JJ, Xiao Y, Jin L, Kuntz KW, Chesworth R, Moyer MP, Bernt KM, Tseng JC, Kung AL, Armstrong SA, Copeland RA, Richon VM, Pollock RM.
    Cancer Cell; 2011 Jul 12; 20(1):53-65. PubMed ID: 21741596
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  • 11. The diverse functions of Dot1 and H3K79 methylation.
    Nguyen AT, Zhang Y.
    Genes Dev; 2011 Jul 01; 25(13):1345-58. PubMed ID: 21724828
    [Abstract] [Full Text] [Related]

  • 12. Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth.
    Wu F, Nie S, Yao Y, Huo T, Li X, Wu X, Zhao J, Lin YL, Zhang Y, Mo Q, Song Y.
    Theranostics; 2021 Jul 01; 11(17):8172-8184. PubMed ID: 34373735
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  • 14. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
    Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhuo D, Vakoc AL, Kim JE, Chen J, Lazar MA, Blobel GA, Vakoc CR.
    Mol Cell Biol; 2008 Apr 01; 28(8):2825-39. PubMed ID: 18285465
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  • 16. The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
    Chen S, Yang Z, Wilkinson AW, Deshpande AJ, Sidoli S, Krajewski K, Strahl BD, Garcia BA, Armstrong SA, Patel DJ, Gozani O.
    Mol Cell; 2015 Oct 15; 60(2):319-27. PubMed ID: 26439302
    [Abstract] [Full Text] [Related]

  • 17. The emerging roles of DOT1L in leukemia and normal development.
    McLean CM, Karemaker ID, van Leeuwen F.
    Leukemia; 2014 Nov 15; 28(11):2131-8. PubMed ID: 24854991
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  • 19. Targeting DOT1L action and interactions in leukemia: the role of DOT1L in transformation and development.
    Barry ER, Corry GN, Rasmussen TP.
    Expert Opin Ther Targets; 2010 Apr 15; 14(4):405-18. PubMed ID: 20230194
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