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Journal Abstract Search

237 related items for PubMed ID: 23916956

  • 1. Expression and/or activity of the SVCT2 ascorbate transporter may be decreased in many aggressive cancers, suggesting potential utility for sodium bicarbonate and dehydroascorbic acid in cancer therapy.
    McCarty MF.
    Med Hypotheses; 2013 Oct; 81(4):664-70. PubMed ID: 23916956
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  • 2. Ascorbic acid, but not dehydroascorbic acid increases intracellular vitamin C content to decrease Hypoxia Inducible Factor -1 alpha activity and reduce malignant potential in human melanoma.
    Fischer AP, Miles SL.
    Biomed Pharmacother; 2017 Feb; 86():502-513. PubMed ID: 28012930
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  • 3. Low ascorbate levels are associated with increased hypoxia-inducible factor-1 activity and an aggressive tumor phenotype in endometrial cancer.
    Kuiper C, Molenaar IG, Dachs GU, Currie MJ, Sykes PH, Vissers MC.
    Cancer Res; 2010 Jul 15; 70(14):5749-58. PubMed ID: 20570889
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  • 4. Increased facilitated transport of dehydroascorbic acid without changes in sodium-dependent ascorbate transport in human melanoma cells.
    Spielholz C, Golde DW, Houghton AN, Nualart F, Vera JC.
    Cancer Res; 1997 Jun 15; 57(12):2529-37. PubMed ID: 9192836
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  • 6. Pharmacokinetic and anti-cancer properties of high dose ascorbate in solid tumours of ascorbate-dependent mice.
    Campbell EJ, Vissers MCM, Wohlrab C, Hicks KO, Strother RM, Bozonet SM, Robinson BA, Dachs GU.
    Free Radic Biol Med; 2016 Oct 15; 99():451-462. PubMed ID: 27567539
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  • 7. Superoxide-dependent uptake of vitamin C in human glioma cells.
    Rodríguez FS, Salazar KA, Jara NA, García-Robles MA, Pérez F, Ferrada LE, Martínez F, Nualart FJ.
    J Neurochem; 2013 Dec 15; 127(6):793-804. PubMed ID: 23859461
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  • 8. Mitochondrial ascorbic acid transport is mediated by a low-affinity form of the sodium-coupled ascorbic acid transporter-2.
    Muñoz-Montesino C, Roa FJ, Peña E, González M, Sotomayor K, Inostroza E, Muñoz CA, González I, Maldonado M, Soliz C, Reyes AM, Vera JC, Rivas CI.
    Free Radic Biol Med; 2014 May 15; 70():241-54. PubMed ID: 24594434
    [Abstract] [Full Text] [Related]

  • 9. Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel.
    Karaczyn A, Ivanov S, Reynolds M, Zhitkovich A, Kasprzak KS, Salnikow K.
    J Cell Biochem; 2006 Apr 01; 97(5):1025-35. PubMed ID: 16288478
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  • 10. Practical strategies for suppressing hypoxia-inducible factor activity in cancer therapy.
    McCarty MF, Barroso-Aranda J, Contreras F.
    Med Hypotheses; 2010 May 01; 74(5):789-97. PubMed ID: 20089365
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  • 12. Functional and physiological role of vitamin C transporters.
    Bürzle M, Hediger MA.
    Curr Top Membr; 2012 May 01; 70():357-75. PubMed ID: 23177992
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  • 15. Restoring physiological levels of ascorbate slows tumor growth and moderates HIF-1 pathway activity in Gulo(-/-) mice.
    Campbell EJ, Vissers MC, Bozonet S, Dyer A, Robinson BA, Dachs GU.
    Cancer Med; 2015 Feb 01; 4(2):303-14. PubMed ID: 25354695
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  • 16. ATR controls cellular adaptation to hypoxia through positive regulation of hypoxia-inducible factor 1 (HIF-1) expression.
    Fallone F, Britton S, Nieto L, Salles B, Muller C.
    Oncogene; 2013 Sep 12; 32(37):4387-96. PubMed ID: 23085754
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  • 18. Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers.
    Bobarykina AY, Minchenko DO, Opentanova IL, Moenner M, Caro J, Esumi H, Minchenko OH.
    Acta Biochim Pol; 2006 Sep 12; 53(4):789-99. PubMed ID: 17143338
    [Abstract] [Full Text] [Related]

  • 19. Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors.
    Xia Y, Choi HK, Lee K.
    Eur J Med Chem; 2012 Mar 12; 49():24-40. PubMed ID: 22305612
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