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261 related items for PubMed ID: 23922098

  • 1. A novel role of the tumor suppressor GNMT in cellular defense against DNA damage.
    Wang YC, Lin WL, Lin YJ, Tang FY, Chen YM, Chiang EP.
    Int J Cancer; 2014 Feb 15; 134(4):799-810. PubMed ID: 23922098
    [Abstract] [Full Text] [Related]

  • 2. Regulation of Folate-Mediated One-Carbon Metabolism by Glycine N-Methyltransferase (GNMT) and Methylenetetrahydrofolate Reductase (MTHFR).
    Wang YC, Wu MT, Lin YJ, Tang FY, Ko HA, Chiang EP.
    J Nutr Sci Vitaminol (Tokyo); 2015 Feb 15; 61 Suppl():S148-50. PubMed ID: 26598833
    [Abstract] [Full Text] [Related]

  • 3. Glycine-N methyltransferase expression in HepG2 cells is involved in methyl group homeostasis by regulating transmethylation kinetics and DNA methylation.
    Wang YC, Tang FY, Chen SY, Chen YM, Chiang EP.
    J Nutr; 2011 May 15; 141(5):777-82. PubMed ID: 21411609
    [Abstract] [Full Text] [Related]

  • 4. GNMT expression increases hepatic folate contents and folate-dependent methionine synthase-mediated homocysteine remethylation.
    Wang YC, Chen YM, Lin YJ, Liu SP, Chiang EP.
    Mol Med; 2011 May 15; 17(5-6):486-94. PubMed ID: 21210071
    [Abstract] [Full Text] [Related]

  • 5. MTHFR Knockdown Assists Cell Defense against Folate Depletion Induced Chromosome Segregation and Uracil Misincorporation in DNA.
    Wu MT, Ye WT, Wang YC, Chen PM, Liu JY, Tai CK, Tang FY, Li JR, Liu CC, Chiang EI.
    Int J Mol Sci; 2021 Aug 30; 22(17):. PubMed ID: 34502300
    [Abstract] [Full Text] [Related]

  • 6. Methyltetrahydrofolate in folate-binding protein glycine N-methyltransferase.
    Luka Z.
    Vitam Horm; 2008 Aug 30; 79():325-45. PubMed ID: 18804700
    [Abstract] [Full Text] [Related]

  • 7. Glycine N-methyltransferase tumor susceptibility gene in the benzo(a)pyrene-detoxification pathway.
    Chen SY, Lin JR, Darbha R, Lin P, Liu TY, Chen YM.
    Cancer Res; 2004 May 15; 64(10):3617-23. PubMed ID: 15150120
    [Abstract] [Full Text] [Related]

  • 8. Nuclear enrichment of folate cofactors and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) protect de novo thymidylate biosynthesis during folate deficiency.
    Field MS, Kamynina E, Agunloye OC, Liebenthal RP, Lamarre SG, Brosnan ME, Brosnan JT, Stover PJ.
    J Biol Chem; 2014 Oct 24; 289(43):29642-50. PubMed ID: 25213861
    [Abstract] [Full Text] [Related]

  • 9. Differential effects of dietary selenium (se) and folate on methyl metabolism in liver and colon of rats.
    Uthus EO, Ross SA, Davis CD.
    Biol Trace Elem Res; 2006 Mar 24; 109(3):201-14. PubMed ID: 16632891
    [Abstract] [Full Text] [Related]

  • 10. A DNA methylation signature associated with the epigenetic repression of glycine N-methyltransferase in human hepatocellular carcinoma.
    Huidobro C, Toraño EG, Fernández AF, Urdinguio RG, Rodríguez RM, Ferrero C, Martínez-Camblor P, Boix L, Bruix J, García-Rodríguez JL, Varela-Rey M, Mato JM, Martínez-Chantar ML, Fraga MF.
    J Mol Med (Berl); 2013 Aug 24; 91(8):939-50. PubMed ID: 23475283
    [Abstract] [Full Text] [Related]

  • 11. Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver.
    Liu SP, Li YS, Chen YJ, Chiang EP, Li AF, Lee YH, Tsai TF, Hsiao M, Huang SF, Chen YM.
    Hepatology; 2007 Nov 24; 46(5):1413-25. PubMed ID: 17937387
    [Abstract] [Full Text] [Related]

  • 12. A novel tumor suppressor function of glycine N-methyltransferase is independent of its catalytic activity but requires nuclear localization.
    DebRoy S, Kramarenko II, Ghose S, Oleinik NV, Krupenko SA, Krupenko NI.
    PLoS One; 2013 Nov 24; 8(7):e70062. PubMed ID: 23936142
    [Abstract] [Full Text] [Related]

  • 13. Hepatic one-carbon metabolism in early folate deficiency in rats.
    Balaghi M, Horne DW, Wagner C.
    Biochem J; 1993 Apr 01; 291 ( Pt 1)(Pt 1):145-9. PubMed ID: 8471033
    [Abstract] [Full Text] [Related]

  • 14. Hepatoma cells from mice deficient in glycine N-methyltransferase have increased RAS signaling and activation of liver kinase B1.
    Martínez-López N, García-Rodríguez JL, Varela-Rey M, Gutiérrez V, Fernández-Ramos D, Beraza N, Aransay AM, Schlangen K, Lozano JJ, Aspichueta P, Luka Z, Wagner C, Evert M, Calvisi DF, Lu SC, Mato JM, Martínez-Chantar ML.
    Gastroenterology; 2012 Sep 01; 143(3):787-798.e13. PubMed ID: 22687285
    [Abstract] [Full Text] [Related]

  • 15. Characterization of a glycine N-methyltransferase gene knockout mouse model for hepatocellular carcinoma: Implications of the gender disparity in liver cancer susceptibility.
    Liao YJ, Liu SP, Lee CM, Yen CH, Chuang PC, Chen CY, Tsai TF, Huang SF, Lee YH, Chen YM.
    Int J Cancer; 2009 Feb 15; 124(4):816-26. PubMed ID: 19035462
    [Abstract] [Full Text] [Related]

  • 16. Dysregulated transmethylation leading to hepatocellular carcinoma compromises redox homeostasis and glucose formation.
    Hughey CC, James FD, Wang Z, Goelzer M, Wasserman DH.
    Mol Metab; 2019 May 15; 23():1-13. PubMed ID: 30850319
    [Abstract] [Full Text] [Related]

  • 17. Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats.
    Nieman KM, Hartz CS, Szegedi SS, Garrow TA, Sparks JD, Schalinske KL.
    Am J Physiol Endocrinol Metab; 2006 Dec 15; 291(6):E1235-42. PubMed ID: 16835399
    [Abstract] [Full Text] [Related]

  • 18. Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
    Martínez-Chantar ML, Vázquez-Chantada M, Ariz U, Martínez N, Varela M, Luka Z, Capdevila A, Rodríguez J, Aransay AM, Matthiesen R, Yang H, Calvisi DF, Esteller M, Fraga M, Lu SC, Wagner C, Mato JM.
    Hepatology; 2008 Apr 15; 47(4):1191-9. PubMed ID: 18318442
    [Abstract] [Full Text] [Related]

  • 19. Glycine N-methyltransferase affects the metabolism of aflatoxin B1 and blocks its carcinogenic effect.
    Yen CH, Hung JH, Ueng YF, Liu SP, Chen SY, Liu HH, Chou TY, Tsai TF, Darbha R, Hsieh LL, Chen YM.
    Toxicol Appl Pharmacol; 2009 Mar 15; 235(3):296-304. PubMed ID: 19146867
    [Abstract] [Full Text] [Related]

  • 20. AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage.
    Fang CC, Wu CF, Liao YJ, Huang SF, Chen M, Chen YA.
    Sci Rep; 2018 Sep 14; 8(1):13802. PubMed ID: 30217986
    [Abstract] [Full Text] [Related]

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