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Journal Abstract Search

220 related items for PubMed ID: 23922653

  • 1. Computational study on the different ligands induced conformation change of β2 adrenergic receptor-Gs protein complex.
    Bai Q, Zhang Y, Ban Y, Liu H, Yao X.
    PLoS One; 2013; 8(7):e68138. PubMed ID: 23922653
    [Abstract] [Full Text] [Related]

  • 2. Studies on the interactions between β2 adrenergic receptor and Gs protein by molecular dynamics simulations.
    Feng Z, Hou T, Li Y.
    J Chem Inf Model; 2012 Apr 23; 52(4):1005-14. PubMed ID: 22404225
    [Abstract] [Full Text] [Related]

  • 3. Analysis of β2AR-Gs and β2AR-Gi complex formation by NMR spectroscopy.
    Ma X, Hu Y, Batebi H, Heng J, Xu J, Liu X, Niu X, Li H, Hildebrand PW, Jin C, Kobilka BK.
    Proc Natl Acad Sci U S A; 2020 Sep 15; 117(37):23096-23105. PubMed ID: 32868434
    [Abstract] [Full Text] [Related]

  • 4. The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein.
    Mafi A, Kim SK, Goddard WA.
    Nat Chem; 2023 Aug 15; 15(8):1127-1137. PubMed ID: 37349378
    [Abstract] [Full Text] [Related]

  • 5. Structural Insights into the Process of GPCR-G Protein Complex Formation.
    Liu X, Xu X, Hilger D, Aschauer P, Tiemann JKS, Du Y, Liu H, Hirata K, Sun X, Guixà-González R, Mathiesen JM, Hildebrand PW, Kobilka BK.
    Cell; 2019 May 16; 177(5):1243-1251.e12. PubMed ID: 31080070
    [Abstract] [Full Text] [Related]

  • 6. Structural features of β2 adrenergic receptor: crystal structures and beyond.
    Bang I, Choi HJ.
    Mol Cells; 2015 May 16; 38(2):105-11. PubMed ID: 25537861
    [Abstract] [Full Text] [Related]

  • 7. Crystal structure of the β2 adrenergic receptor-Gs protein complex.
    Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK.
    Nature; 2011 Jul 19; 477(7366):549-55. PubMed ID: 21772288
    [Abstract] [Full Text] [Related]

  • 8. Microsecond Molecular Dynamics Simulations Provide Insight into the Allosteric Mechanism of the Gs Protein Uncoupling from the β2 Adrenergic Receptor.
    Sun X, Ågren H, Tu Y.
    J Phys Chem B; 2014 Dec 26; 118(51):14737-44. PubMed ID: 25453446
    [Abstract] [Full Text] [Related]

  • 9. Single-molecule analysis of ligand efficacy in β2AR-G-protein activation.
    Gregorio GG, Masureel M, Hilger D, Terry DS, Juette M, Zhao H, Zhou Z, Perez-Aguilar JM, Hauge M, Mathiasen S, Javitch JA, Weinstein H, Kobilka BK, Blanchard SC.
    Nature; 2017 Jul 06; 547(7661):68-73. PubMed ID: 28607487
    [Abstract] [Full Text] [Related]

  • 10. Allosteric coupling from G protein to the agonist-binding pocket in GPCRs.
    DeVree BT, Mahoney JP, Vélez-Ruiz GA, Rasmussen SG, Kuszak AJ, Edwald E, Fung JJ, Manglik A, Masureel M, Du Y, Matt RA, Pardon E, Steyaert J, Kobilka BK, Sunahara RK.
    Nature; 2016 Jul 07; 535(7610):182-6. PubMed ID: 27362234
    [Abstract] [Full Text] [Related]

  • 11. Ligand induced change of β2 adrenergic receptor from active to inactive conformation and its implication for the closed/open state of the water channel: insight from molecular dynamics simulation, free energy calculation and Markov state model analysis.
    Bai Q, Pérez-Sánchez H, Zhang Y, Shao Y, Shi D, Liu H, Yao X.
    Phys Chem Chem Phys; 2014 Aug 14; 16(30):15874-85. PubMed ID: 24962153
    [Abstract] [Full Text] [Related]

  • 12. Elucidation of a dynamic interplay between a beta-2 adrenergic receptor, its agonist, and stimulatory G protein.
    Han Y, Dawson JRD, DeMarco KR, Rouen KC, Bekker S, Yarov-Yarovoy V, Clancy CE, Xiang YK, Vorobyov I.
    Proc Natl Acad Sci U S A; 2023 Mar 07; 120(10):e2215916120. PubMed ID: 36853938
    [Abstract] [Full Text] [Related]

  • 13. Exploring the Activation Process of the β2AR-Gs Complex.
    Bai C, Wang J, Mondal D, Du Y, Ye RD, Warshel A.
    J Am Chem Soc; 2021 Jul 28; 143(29):11044-11051. PubMed ID: 34255502
    [Abstract] [Full Text] [Related]

  • 14. Search for β2 adrenergic receptor ligands by virtual screening via grid computing and investigation of binding modes by docking and molecular dynamics simulations.
    Bai Q, Shao Y, Pan D, Zhang Y, Liu H, Yao X.
    PLoS One; 2014 Jul 28; 9(9):e107837. PubMed ID: 25229694
    [Abstract] [Full Text] [Related]

  • 15. Different effects of Gsalpha splice variants on beta2-adrenoreceptor-mediated signaling. The beta2-adrenoreceptor coupled to the long splice variant of Gsalpha has properties of a constitutively active receptor.
    Seifert R, Wenzel-Seifert K, Lee TW, Gether U, Sanders-Bush E, Kobilka BK.
    J Biol Chem; 1998 Feb 27; 273(9):5109-16. PubMed ID: 9478963
    [Abstract] [Full Text] [Related]

  • 16. Development and characterization of pepducins as Gs-biased allosteric agonists.
    Carr R, Du Y, Quoyer J, Panettieri RA, Janz JM, Bouvier M, Kobilka BK, Benovic JL.
    J Biol Chem; 2014 Dec 26; 289(52):35668-84. PubMed ID: 25395624
    [Abstract] [Full Text] [Related]

  • 17. Dynamic behavior of fully solvated beta2-adrenergic receptor, embedded in the membrane with bound agonist or antagonist.
    Spijker P, Vaidehi N, Freddolino PL, Hilbers PA, Goddard WA.
    Proc Natl Acad Sci U S A; 2006 Mar 28; 103(13):4882-7. PubMed ID: 16551744
    [Abstract] [Full Text] [Related]

  • 18. GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.
    Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, Kobilka BK.
    Science; 2007 Nov 23; 318(5854):1266-73. PubMed ID: 17962519
    [Abstract] [Full Text] [Related]

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  • 20. Different conformational responses of the β2-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline.
    Yang F, Ling S, Zhou Y, Zhang Y, Lv P, Liu S, Fang W, Sun W, Hu LA, Zhang L, Shi P, Tian C.
    Natl Sci Rev; 2021 Sep 23; 8(9):nwaa284. PubMed ID: 39040950
    [Abstract] [Full Text] [Related]

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