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293 related items for PubMed ID: 23931689

  • 1. Role of a highly conserved proline-126 in ThDP binding of Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA, Gedi V, Lee SC, Koh SH, Yoon MY.
    Enzyme Microb Technol; 2013 Sep 10; 53(4):243-9. PubMed ID: 23931689
    [Abstract] [Full Text] [Related]

  • 2. Functional evaluation of residues in the herbicide-binding site of Mycobacterium tuberculosis acetohydroxyacid synthase by site-directed mutagenesis.
    Jung IP, Cho JH, Koo BS, Yoon MY.
    Enzyme Microb Technol; 2015 Oct 10; 78():18-26. PubMed ID: 26215340
    [Abstract] [Full Text] [Related]

  • 3. Structural and functional significance of the highly-conserved residues in Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA, Moon JY, Kim MS, Koo BS, Yoon MY.
    Enzyme Microb Technol; 2014 May 10; 58-59():52-9. PubMed ID: 24731825
    [Abstract] [Full Text] [Related]

  • 4. Structural and functional evaluation of three well-conserved serine residues in tobacco acetohydroxyacid synthase.
    Yoon MY, Gedi V, Kim J, Park Y, Kim DE, Park EH, Choi JD.
    Biochimie; 2010 Jan 10; 92(1):65-70. PubMed ID: 19825392
    [Abstract] [Full Text] [Related]

  • 5. Many of the functional differences between acetohydroxyacid synthase (AHAS) isozyme I and other AHASs are a result of the rapid formation and breakdown of the covalent acetolactate-thiamin diphosphate adduct in AHAS I.
    Belenky I, Steinmetz A, Vyazmensky M, Barak Z, Tittmann K, Chipman DM.
    FEBS J; 2012 Jun 10; 279(11):1967-79. PubMed ID: 22443469
    [Abstract] [Full Text] [Related]

  • 6. Binding and activation of thiamin diphosphate in acetohydroxyacid synthase.
    Bar-Ilan A, Balan V, Tittmann K, Golbik R, Vyazmensky M, Hübner G, Barak Z, Chipman DM.
    Biochemistry; 2001 Oct 02; 40(39):11946-54. PubMed ID: 11570896
    [Abstract] [Full Text] [Related]

  • 7. Characterization of acetohydroxyacid synthase from Mycobacterium tuberculosis and the identification of its new inhibitor from the screening of a chemical library.
    Choi KJ, Yu YG, Hahn HG, Choi JD, Yoon MY.
    FEBS Lett; 2005 Aug 29; 579(21):4903-10. PubMed ID: 16111681
    [Abstract] [Full Text] [Related]

  • 8. Significant catalytic roles for Glu47 and Gln 110 in all four of the C-C bond-making and -breaking steps of the reactions of acetohydroxyacid synthase II.
    Vyazmensky M, Steinmetz A, Meyer D, Golbik R, Barak Z, Tittmann K, Chipman DM.
    Biochemistry; 2011 Apr 19; 50(15):3250-60. PubMed ID: 21370850
    [Abstract] [Full Text] [Related]

  • 9. Thiamin auxotrophy in yeast through altered cofactor dependence of the enzyme acetohydroxyacid synthase.
    Byrne KL, Meacock PA.
    Microbiology (Reading); 2001 Sep 19; 147(Pt 9):2389-2398. PubMed ID: 11535779
    [Abstract] [Full Text] [Related]

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  • 11. Characterization of acetohydroxyacid synthase I from Escherichia coli K-12 and identification of its inhibitors.
    Pham NC, Moon JY, Cho JH, Lee SJ, Park JS, Kim DE, Park Y, Yoon MY.
    Biosci Biotechnol Biochem; 2010 Sep 19; 74(11):2281-6. PubMed ID: 21071847
    [Abstract] [Full Text] [Related]

  • 12. Mutational analysis of critical residues of FAD-independent catabolic acetolactate synthase from Enterococcus faecalis V583.
    Lee SC, Jung IP, Baig IA, Chien PN, La IJ, Yoon MY.
    Int J Biol Macromol; 2015 Jan 19; 72():104-9. PubMed ID: 25128823
    [Abstract] [Full Text] [Related]

  • 13. Effects of deletions at the C-terminus of tobacco acetohydroxyacid synthase on the enzyme activity and cofactor binding.
    Kim J, Beak DG, Kim YT, Choi JD, Yoon MY.
    Biochem J; 2004 Nov 15; 384(Pt 1):59-68. PubMed ID: 15521822
    [Abstract] [Full Text] [Related]

  • 14. Homology modeling of the structure of bacterial acetohydroxy acid synthase and examination of the active site by site-directed mutagenesis.
    Ibdah M, Bar-Ilan A, Livnah O, Schloss JV, Barak Z, Chipman DM.
    Biochemistry; 1996 Dec 17; 35(50):16282-91. PubMed ID: 8973202
    [Abstract] [Full Text] [Related]

  • 15. Valine 375 and phenylalanine 109 confer affinity and specificity for pyruvate as donor substrate in acetohydroxy acid synthase isozyme II from Escherichia coli.
    Steinmetz A, Vyazmensky M, Meyer D, Barak ZE, Golbik R, Chipman DM, Tittmann K.
    Biochemistry; 2010 Jun 29; 49(25):5188-99. PubMed ID: 20504042
    [Abstract] [Full Text] [Related]

  • 16. Biosynthesis of 2-aceto-2-hydroxy acids: acetolactate synthases and acetohydroxyacid synthases.
    Chipman D, Barak Z, Schloss JV.
    Biochim Biophys Acta; 1998 Jun 29; 1385(2):401-19. PubMed ID: 9655946
    [Abstract] [Full Text] [Related]

  • 17. Cloning, characterization and evaluation of potent inhibitors of Shigella sonnei acetohydroxyacid synthase catalytic subunit.
    Lim WM, Baig IJ, La IJ, Choi JD, Kim DE, Kim SK, Hyun JW, Kim G, Kang CH, Kim YJ, Yoon MY.
    Biochim Biophys Acta; 2011 Dec 29; 1814(12):1825-31. PubMed ID: 22015678
    [Abstract] [Full Text] [Related]

  • 18. Biochemical characterization and evaluation of potent inhibitors of the Pseudomonas aeruginosa PA01 acetohydroxyacid synthase.
    Cho JH, Lee MY, Baig IA, Ha NR, Kim J, Yoon MY.
    Biochimie; 2013 Jul 29; 95(7):1411-21. PubMed ID: 23523771
    [Abstract] [Full Text] [Related]

  • 19. Role of a conserved arginine in the mechanism of acetohydroxyacid synthase: catalysis of condensation with a specific ketoacid substrate.
    Engel S, Vyazmensky M, Vinogradov M, Berkovich D, Bar-Ilan A, Qimron U, Rosiansky Y, Barak Z, Chipman DM.
    J Biol Chem; 2004 Jun 04; 279(23):24803-12. PubMed ID: 15044456
    [Abstract] [Full Text] [Related]

  • 20. Identification of the catalytic subunit of acetohydroxyacid synthase in Haemophilus influenzae and its potent inhibitors.
    Choi KJ, Noh KM, Kim DE, Ha BH, Kim EE, Yoon MY.
    Arch Biochem Biophys; 2007 Oct 01; 466(1):24-30. PubMed ID: 17718999
    [Abstract] [Full Text] [Related]

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