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Journal Abstract Search

493 related items for PubMed ID: 23932451

  • 1. Synthesis and biological evaluation of berberine-thiophenyl hybrids as multi-functional agents: Inhibition of acetylcholinesterase, butyrylcholinesterase, and Aβ aggregation and antioxidant activity.
    Su T, Xie S, Wei H, Yan J, Huang L, Li X.
    Bioorg Med Chem; 2013 Sep 15; 21(18):5830-40. PubMed ID: 23932451
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of a new series of berberine derivatives as dual inhibitors of acetylcholinesterase and butyrylcholinesterase.
    Huang L, Luo Z, He F, Lu J, Li X.
    Bioorg Med Chem; 2010 Jun 15; 18(12):4475-84. PubMed ID: 20471843
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
    Shan WJ, Huang L, Zhou Q, Meng FC, Li XS.
    Eur J Med Chem; 2011 Dec 15; 46(12):5885-93. PubMed ID: 22019228
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors.
    Huang L, Shi A, He F, Li X.
    Bioorg Med Chem; 2010 Feb 15; 18(3):1244-51. PubMed ID: 20056426
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of cholinesterase activity and amyloid aggregation by berberine-phenyl-benzoheterocyclic and tacrine-phenyl-benzoheterocyclic hybrids.
    Huang L, Su T, Shan W, Luo Z, Sun Y, He F, Li X.
    Bioorg Med Chem; 2012 May 01; 20(9):3038-48. PubMed ID: 22472046
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, biological evaluation and molecular modeling of novel triazole-containing berberine derivatives as acetylcholinesterase and β-amyloid aggregation inhibitors.
    Shi A, Huang L, Lu C, He F, Li X.
    Bioorg Med Chem; 2011 Apr 01; 19(7):2298-305. PubMed ID: 21397508
    [Abstract] [Full Text] [Related]

  • 7. Multifunctional novel Diallyl disulfide (DADS) derivatives with β-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease.
    Manral A, Saini V, Meena P, Tiwari M.
    Bioorg Med Chem; 2015 Oct 01; 23(19):6389-403. PubMed ID: 26337018
    [Abstract] [Full Text] [Related]

  • 8. Synthesis, biological activity and molecular modeling studies on 1H-benzimidazole derivatives as acetylcholinesterase inhibitors.
    Alpan AS, Parlar S, Carlino L, Tarikogullari AH, Alptüzün V, Güneş HS.
    Bioorg Med Chem; 2013 Sep 01; 21(17):4928-37. PubMed ID: 23891231
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of some new 3-coumaranone and coumarin derivatives as dual inhibitors of acetyl- and butyrylcholinesterase.
    Alipour M, Khoobi M, Nadri H, Sakhteman A, Moradi A, Ghandi M, Foroumadi A, Shafiee A.
    Arch Pharm (Weinheim); 2013 Aug 01; 346(8):577-87. PubMed ID: 23852709
    [Abstract] [Full Text] [Related]

  • 10. Structure-activity relationship studies of benzyl-, phenethyl-, and pyridyl-substituted tetrahydroacridin-9-amines as multitargeting agents to treat Alzheimer's disease.
    Osman W, Mohamed T, Sit VM, Vasefi MS, Beazely MA, Rao PP.
    Chem Biol Drug Des; 2016 Nov 01; 88(5):710-723. PubMed ID: 27282589
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as dual inhibitors for cholinesterases and amyloid beta aggregation.
    Luo W, Li YP, He Y, Huang SL, Tan JH, Ou TM, Li D, Gu LQ, Huang ZS.
    Bioorg Med Chem; 2011 Jan 15; 19(2):763-70. PubMed ID: 21211982
    [Abstract] [Full Text] [Related]

  • 12. Novel tacrine-ebselen hybrids with improved cholinesterase inhibitory, hydrogen peroxide and peroxynitrite scavenging activity.
    Mao F, Chen J, Zhou Q, Luo Z, Huang L, Li X.
    Bioorg Med Chem Lett; 2013 Dec 15; 23(24):6737-42. PubMed ID: 24220172
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and evaluation of 7,8-dehydrorutaecarpine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
    He Y, Yao PF, Chen SB, Huang ZH, Huang SL, Tan JH, Li D, Gu LQ, Huang ZS.
    Eur J Med Chem; 2013 May 15; 63():299-312. PubMed ID: 23501115
    [Abstract] [Full Text] [Related]

  • 14. Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Brunhofer G, Fallarero A, Karlsson D, Batista-Gonzalez A, Shinde P, Gopi Mohan C, Vuorela P.
    Bioorg Med Chem; 2012 Nov 15; 20(22):6669-79. PubMed ID: 23062825
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis, and bioevaluation of benzamides: novel acetylcholinesterase inhibitors with multi-functions on butylcholinesterase, Aβ aggregation, and β-secretase.
    Peng DY, Sun Q, Zhu XL, Lin HY, Chen Q, Yu NX, Yang WC, Yang GF.
    Bioorg Med Chem; 2012 Nov 15; 20(22):6739-50. PubMed ID: 23041347
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Bolea I, Juárez-Jiménez J, de Los Ríos C, Chioua M, Pouplana R, Luque FJ, Unzeta M, Marco-Contelles J, Samadi A.
    J Med Chem; 2011 Dec 22; 54(24):8251-70. PubMed ID: 22023459
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and evaluation of novel 4-dimethylamine flavonoid derivatives as potential multi-functional anti-Alzheimer agents.
    Luo W, Su YB, Hong C, Tian RG, Su LP, Wang YQ, Li Y, Yue JJ, Wang CJ.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7275-82. PubMed ID: 24148835
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS, Xie SS, Li SY, Pan LF, Wang XB, Kong LY.
    Bioorg Med Chem; 2014 Nov 01; 22(21):6089-104. PubMed ID: 25282654
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase.
    Catto M, Berezin AA, Lo Re D, Loizou G, Demetriades M, De Stradis A, Campagna F, Koutentis PA, Carotti A.
    Eur J Med Chem; 2012 Dec 01; 58():84-97. PubMed ID: 23108363
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and evaluation of flavonoid derivatives as potential multifunctional acetylcholinesterase inhibitors against Alzheimer's disease.
    Li RS, Wang XB, Hu XJ, Kong LY.
    Bioorg Med Chem Lett; 2013 May 01; 23(9):2636-41. PubMed ID: 23511019
    [Abstract] [Full Text] [Related]

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