These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Paclitaxel and beta-lapachone synergistically induce apoptosis in human retinoblastoma Y79 cells by downregulating the levels of phospho-Akt. D'Anneo A, Augello G, Santulli A, Giuliano M, di Fiore R, Messina C, Tesoriere G, Vento R. J Cell Physiol; 2010 Feb; 222(2):433-43. PubMed ID: 19918798 [Abstract] [Full Text] [Related]
4. The LXR-623-induced long non-coding RNA LINC01125 suppresses the proliferation of breast cancer cells via PTEN/AKT/p53 signaling pathway. Wan W, Hou Y, Wang K, Cheng Y, Pu X, Ye X. Cell Death Dis; 2019 Mar 13; 10(3):248. PubMed ID: 30867411 [Abstract] [Full Text] [Related]
5. SPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival. Fenouille N, Puissant A, Tichet M, Zimniak G, Abbe P, Mallavialle A, Rocchi S, Ortonne JP, Deckert M, Ballotti R, Tartare-Deckert S. Oncogene; 2011 Dec 08; 30(49):4887-900. PubMed ID: 21685937 [Abstract] [Full Text] [Related]
6. Cytosolic and mitochondrial ROS production resulted in apoptosis induction in breast cancer cells treated with Crocin: The role of FOXO3a, PTEN and AKT signaling. Nasimian A, Farzaneh P, Tamanoi F, Bathaie SZ. Biochem Pharmacol; 2020 Jul 08; 177():113999. PubMed ID: 32353423 [Abstract] [Full Text] [Related]
7. Parthenolide promotes the ubiquitination of MDM2 and activates p53 cellular functions. Gopal YN, Chanchorn E, Van Dyke MW. Mol Cancer Ther; 2009 Mar 08; 8(3):552-62. PubMed ID: 19276167 [Abstract] [Full Text] [Related]
8. Triggering p53 activation is essential in ziyuglycoside I-induced human retinoblastoma WERI-Rb-1 cell apoptosis. Zhu X, Wang K, Yao Y, Zhang K, Zhou F, Zhu L. J Biochem Mol Toxicol; 2018 Jan 08; 32(1):. PubMed ID: 28960612 [Abstract] [Full Text] [Related]
10. HDACi inhibits liposarcoma via targeting of the MDM2-p53 signaling axis and PTEN, irrespective of p53 mutational status. Ou WB, Zhu J, Eilers G, Li X, Kuang Y, Liu L, Mariño-Enríquez A, Yan Z, Li H, Meng F, Zhou H, Sheng Q, Fletcher JA. Oncotarget; 2015 Apr 30; 6(12):10510-20. PubMed ID: 25888633 [Abstract] [Full Text] [Related]
11. Ganglioside GM3 modulates tumor suppressor PTEN-mediated cell cycle progression--transcriptional induction of p21(WAF1) and p27(kip1) by inhibition of PI-3K/AKT pathway. Choi HJ, Chung TW, Kang SK, Lee YC, Ko JH, Kim JG, Kim CH. Glycobiology; 2006 Jul 30; 16(7):573-83. PubMed ID: 16574813 [Abstract] [Full Text] [Related]
12. Apoptosis-induced effects of extract from Artemisia annua Linné by modulating PTEN/p53/PDK1/Akt/ signal pathways through PTEN/p53-independent manner in HCT116 colon cancer cells. Kim EJ, Kim GT, Kim BM, Lim EG, Kim SY, Kim YM. BMC Complement Altern Med; 2017 Apr 28; 17(1):236. PubMed ID: 28454566 [Abstract] [Full Text] [Related]
15. Phosphorylation of human p53 at serine 46 determines promoter selection and whether apoptosis is attenuated or amplified. Mayo LD, Seo YR, Jackson MW, Smith ML, Rivera Guzman J, Korgaonkar CK, Donner DB. J Biol Chem; 2005 Jul 15; 280(28):25953-9. PubMed ID: 15843377 [Abstract] [Full Text] [Related]
16. Research on miR-126 in glioma targeted regulation of PTEN/PI3K/Akt and MDM2-p53 pathways. Chen SR, Cai WP, Dai XJ, Guo AS, Chen HP, Lin GS, Lin RS. Eur Rev Med Pharmacol Sci; 2019 Apr 15; 23(8):3461-3470. PubMed ID: 31081101 [Abstract] [Full Text] [Related]
17. Mild oxidative stress induces S-glutathionylation of STAT3 and enhances chemosensitivity of tumoural cells to chemotherapeutic drugs. Butturini E, Carcereri de Prati A, Chiavegato G, Rigo A, Cavalieri E, Darra E, Mariotto S. Free Radic Biol Med; 2013 Dec 15; 65():1322-1330. PubMed ID: 24095958 [Abstract] [Full Text] [Related]
19. MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism. Ren G, Yang EJ, Tao S, Mou PK, Pu Y, Chen LJ, Shim JS. Int J Biol Sci; 2023 Dec 15; 19(11):3544-3557. PubMed ID: 37496993 [Abstract] [Full Text] [Related]
20. Over-expression of PTEN sensitizes human ovarian cancer cells to cisplatin-induced apoptosis in a p53-dependent manner. Yan X, Fraser M, Qiu Q, Tsang BK. Gynecol Oncol; 2006 Aug 15; 102(2):348-55. PubMed ID: 16545436 [Abstract] [Full Text] [Related] Page: [Next] [New Search]