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198 related items for PubMed ID: 23957911

  • 1. Structural basis for regulation of human glucokinase by glucokinase regulatory protein.
    Beck T, Miller BG.
    Biochemistry; 2013 Sep 10; 52(36):6232-9. PubMed ID: 23957911
    [Abstract] [Full Text] [Related]

  • 2. Antidiabetic Disruptors of the Glucokinase-Glucokinase Regulatory Protein Complex Reorganize a Coulombic Interface.
    Martinez JA, Xiao Q, Zakarian A, Miller BG.
    Biochemistry; 2017 Jun 20; 56(24):3150-3157. PubMed ID: 28516783
    [Abstract] [Full Text] [Related]

  • 3. Kinetic Basis of Carbohydrate-Mediated Inhibition of Human Glucokinase by the Glucokinase Regulatory Protein.
    Casey AK, Miller BG.
    Biochemistry; 2016 May 31; 55(21):2899-902. PubMed ID: 27174229
    [Abstract] [Full Text] [Related]

  • 4. The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver.
    Beer NL, Tribble ND, McCulloch LJ, Roos C, Johnson PR, Orho-Melander M, Gloyn AL.
    Hum Mol Genet; 2009 Nov 01; 18(21):4081-8. PubMed ID: 19643913
    [Abstract] [Full Text] [Related]

  • 5. A panel of diverse assays to interrogate the interaction between glucokinase and glucokinase regulatory protein, two vital proteins in human disease.
    Rees MG, Davis MI, Shen M, Titus S, Raimondo A, Barrett A, Gloyn AL, Collins FS, Simeonov A.
    PLoS One; 2014 Nov 01; 9(2):e89335. PubMed ID: 24586696
    [Abstract] [Full Text] [Related]

  • 6. Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes.
    Paliwal A, Paliwal V, Jain S, Paliwal S, Sharma S.
    Mini Rev Med Chem; 2024 Nov 01; 24(7):674-688. PubMed ID: 37612862
    [Abstract] [Full Text] [Related]

  • 7. Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase.
    Choi JM, Seo MH, Kyeong HH, Kim E, Kim HS.
    Proc Natl Acad Sci U S A; 2013 Jun 18; 110(25):10171-6. PubMed ID: 23733961
    [Abstract] [Full Text] [Related]

  • 8. Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk.
    Rees MG, Wincovitch S, Schultz J, Waterstradt R, Beer NL, Baltrusch S, Collins FS, Gloyn AL.
    Diabetologia; 2012 Jan 18; 55(1):114-22. PubMed ID: 22038520
    [Abstract] [Full Text] [Related]

  • 9. Theoretical investigations on the interactions of glucokinase regulatory protein with fructose phosphates.
    Ling B, Yan X, Sun M, Bi S.
    Comput Biol Chem; 2016 Feb 18; 60():21-31. PubMed ID: 26629747
    [Abstract] [Full Text] [Related]

  • 10. A report of 2 new cases of MODY2 and review of the literature: implications in the search for type 2 diabetes drugs.
    Shammas C, Neocleous V, Phelan MM, Lian LY, Skordis N, Phylactou LA.
    Metabolism; 2013 Nov 18; 62(11):1535-42. PubMed ID: 23890519
    [Abstract] [Full Text] [Related]

  • 11. Impaired GK-GKRP interaction rather than direct GK activation worsens lipid profiles and contributes to long-term complications: a Mendelian randomization study.
    Wang K, Shi M, Luk AOY, Kong APS, Ma RCW, Li C, Chen L, Chow E, Chan JCN.
    Cardiovasc Diabetol; 2024 Jun 29; 23(1):228. PubMed ID: 38951793
    [Abstract] [Full Text] [Related]

  • 12. Insights into the structure and regulation of glucokinase from a novel mutation (V62M), which causes maturity-onset diabetes of the young.
    Gloyn AL, Odili S, Zelent D, Buettger C, Castleden HA, Steele AM, Stride A, Shiota C, Magnuson MA, Lorini R, d'Annunzio G, Stanley CA, Kwagh J, van Schaftingen E, Veiga-da-Cunha M, Barbetti F, Dunten P, Han Y, Grimsby J, Taub R, Ellard S, Hattersley AT, Matschinsky FM.
    J Biol Chem; 2005 Apr 08; 280(14):14105-13. PubMed ID: 15677479
    [Abstract] [Full Text] [Related]

  • 13. Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis.
    Tamayo NA, Norman MH, Bartberger MD, Hong FT, Bo Y, Liu L, Nishimura N, Yang KC, Tadesse S, Fotsch C, Chen J, Chmait S, Cupples R, Hale C, Jordan SR, Lloyd DJ, Sivits G, Van G, St Jean DJ.
    J Med Chem; 2015 Jun 11; 58(11):4462-82. PubMed ID: 25914941
    [Abstract] [Full Text] [Related]

  • 14. Differences in regulatory properties between human and rat glucokinase regulatory protein.
    Brocklehurst KJ, Davies RA, Agius L.
    Biochem J; 2004 Mar 01; 378(Pt 2):693-7. PubMed ID: 14627435
    [Abstract] [Full Text] [Related]

  • 15. Glucokinase regulatory protein: complexity at the crossroads of triglyceride and glucose metabolism.
    Raimondo A, Rees MG, Gloyn AL.
    Curr Opin Lipidol; 2015 Apr 01; 26(2):88-95. PubMed ID: 25692341
    [Abstract] [Full Text] [Related]

  • 16. Crystal structure of glucokinase regulatory protein.
    Pautsch A, Stadler N, Löhle A, Rist W, Berg A, Glocker L, Nar H, Reinert D, Lenter M, Heckel A, Schnapp G, Kauschke SG.
    Biochemistry; 2013 May 21; 52(20):3523-31. PubMed ID: 23621087
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
    Mukhtar MH, Payne VA, Arden C, Harbottle A, Khan S, Lange AJ, Agius L.
    Am J Physiol Regul Integr Comp Physiol; 2008 Mar 21; 294(3):R766-74. PubMed ID: 18199594
    [Abstract] [Full Text] [Related]

  • 18. Functional analysis of human glucokinase gene mutations causing MODY2: exploring the regulatory mechanisms of glucokinase activity.
    García-Herrero CM, Galán M, Vincent O, Flández B, Gargallo M, Delgado-Alvarez E, Blázquez E, Navas MA.
    Diabetologia; 2007 Feb 21; 50(2):325-33. PubMed ID: 17186219
    [Abstract] [Full Text] [Related]

  • 19. Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.
    Farrelly D, Brown KS, Tieman A, Ren J, Lira SA, Hagan D, Gregg R, Mookhtiar KA, Hariharan N.
    Proc Natl Acad Sci U S A; 1999 Dec 07; 96(25):14511-6. PubMed ID: 10588736
    [Abstract] [Full Text] [Related]

  • 20. The regulatory protein of liver glucokinase.
    van Schaftingen E, Vandercammen A, Detheux M, Davies DR.
    Adv Enzyme Regul; 1992 Dec 07; 32():133-48. PubMed ID: 1496915
    [Abstract] [Full Text] [Related]

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