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273 related items for PubMed ID: 23959146

  • 1. Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat.
    Paul KB, Hedge JM, Macherla C, Filer DL, Burgess E, Simmons SO, Crofton KM, Hornung MW.
    Toxicology; 2013 Oct 04; 312():97-107. PubMed ID: 23959146
    [Abstract] [Full Text] [Related]

  • 2. Development of a thyroperoxidase inhibition assay for high-throughput screening.
    Paul KB, Hedge JM, Rotroff DM, Hornung MW, Crofton KM, Simmons SO.
    Chem Res Toxicol; 2014 Mar 17; 27(3):387-99. PubMed ID: 24383450
    [Abstract] [Full Text] [Related]

  • 3. Effect of antithyroid agents 6-propyl-2-thiouracil and 1-mehtyl-2-mercaptoimidazole on human thyroid iodine peroxidase.
    Nagasaka A, Hidaka H.
    J Clin Endocrinol Metab; 1976 Jul 17; 43(1):152-8. PubMed ID: 947933
    [Abstract] [Full Text] [Related]

  • 4. Extrapolating In Vitro Screening Assay Data for Thyroperoxidase Inhibition to Predict Serum Thyroid Hormones in the Rat.
    Hassan I, El-Masri H, Ford J, Brennan A, Handa S, Paul Friedman K, Gilbert ME.
    Toxicol Sci; 2020 Feb 01; 173(2):280-292. PubMed ID: 31697382
    [Abstract] [Full Text] [Related]

  • 5. Thyroid organotypic rat and human cultures used to investigate drug effects on thyroid function, hormone synthesis and release pathways.
    Vickers AE, Heale J, Sinclair JR, Morris S, Rowe JM, Fisher RL.
    Toxicol Appl Pharmacol; 2012 Apr 01; 260(1):81-8. PubMed ID: 22342233
    [Abstract] [Full Text] [Related]

  • 6. Methimazole and propylthiouracil increase cellular thyroid peroxidase activity and thyroid peroxidase mRNA in cultured porcine thyroid follicles.
    Sugawara M, Sugawara Y, Wen K.
    Thyroid; 1999 May 01; 9(5):513-8. PubMed ID: 10365684
    [Abstract] [Full Text] [Related]

  • 7. A comparison of potency differences among thyroid peroxidase (TPO) inhibitors to induce developmental toxicity and other thyroid gland-linked toxicities in humans and rats.
    Motonaga K, Ota M, Odawara K, Saito S, Welsch F.
    Regul Toxicol Pharmacol; 2016 Oct 01; 80():283-90. PubMed ID: 27350053
    [Abstract] [Full Text] [Related]

  • 8. Preferential inhibition of thyroxine and 3,5,3'-triiodothyronine formation by propylthiouracil and methylmercaptoimidazole in thyroid peroxidase-catalyzed iodination of thyroglobulin.
    Engler H, Taurog A, Dorris ML.
    Endocrinology; 1982 Jan 01; 110(1):190-7. PubMed ID: 7053983
    [Abstract] [Full Text] [Related]

  • 9. Mechanism of action of thioureylene antithyroid drugs in the rat: possible inactivation of thyroid peroxidase by propylthiouracil.
    Shiroozu A, Taurog A, Engler H, Dorris ML.
    Endocrinology; 1983 Jul 01; 113(1):362-70. PubMed ID: 6861708
    [Abstract] [Full Text] [Related]

  • 10. Coupling of iodotyrosine catalyzed by human thyroid peroxidase in vitro.
    Sugawara M.
    J Clin Endocrinol Metab; 1985 Jun 01; 60(6):1069-75. PubMed ID: 3838997
    [Abstract] [Full Text] [Related]

  • 11. The mechanism of action of the thioureylene antithyroid drugs.
    Taurog A.
    Endocrinology; 1976 Apr 01; 98(4):1031-46. PubMed ID: 1278093
    [Abstract] [Full Text] [Related]

  • 12. Studies on the goitrogenic mechanism of action of N,N,N',N'-tetramethylthiourea.
    Freyberger A, Ahr HJ.
    Toxicology; 2006 Jan 16; 217(2-3):169-75. PubMed ID: 16297522
    [Abstract] [Full Text] [Related]

  • 13. In Vitro, Ex Vivo, and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles.
    Hornung MW, Kosian PA, Haselman JT, Korte JJ, Challis K, Macherla C, Nevalainen E, Degitz SJ.
    Toxicol Sci; 2015 Aug 16; 146(2):254-64. PubMed ID: 25953703
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of thyroid hormone release from cultured amphibian thyroid glands by methimazole, 6-propylthiouracil, and perchlorate.
    Hornung MW, Degitz SJ, Korte LM, Olson JM, Kosian PA, Linnum AL, Tietge JE.
    Toxicol Sci; 2010 Nov 16; 118(1):42-51. PubMed ID: 20530234
    [Abstract] [Full Text] [Related]

  • 15. Perinatal exposure to the thyroperoxidase inhibitors methimazole and amitrole perturbs thyroid hormone system signaling and alters motor activity in rat offspring.
    Ramhøj L, Svingen T, Frädrich C, Rijntjes E, Wirth EK, Pedersen K, Köhrle J, Axelstad M.
    Toxicol Lett; 2022 Jan 01; 354():44-55. PubMed ID: 34757178
    [Abstract] [Full Text] [Related]

  • 16. A new class of propylthiouracil analogs: comparison of 5'-deiodinase inhibition and antithyroid activity.
    Nogimori T, Braverman LE, Taurog A, Fang SL, Wright G, Emerson CH.
    Endocrinology; 1986 Apr 01; 118(4):1598-605. PubMed ID: 3948793
    [Abstract] [Full Text] [Related]

  • 17. An assay for screening xenobiotics for inhibition of rat thyroid gland peroxidase activity.
    Price RJ, Burch R, Chatham LR, Higgins LG, Currie RA, Lake BG.
    Xenobiotica; 2020 Mar 01; 50(3):318-322. PubMed ID: 31180273
    [Abstract] [Full Text] [Related]

  • 18. Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries.
    Paul Friedman K, Watt ED, Hornung MW, Hedge JM, Judson RS, Crofton KM, Houck KA, Simmons SO.
    Toxicol Sci; 2016 May 01; 151(1):160-80. PubMed ID: 26884060
    [Abstract] [Full Text] [Related]

  • 19. A reexamination of the proposed inactivation of thyroid peroxidase in the rat thyroid by propylthiouracil.
    Taurog A, Dorris ML.
    Endocrinology; 1989 Jun 01; 124(6):3038-42. PubMed ID: 2656250
    [Abstract] [Full Text] [Related]

  • 20. Minocycline and the thyroid: antithyroid effects of the drug, and the role of thyroid peroxidase in minocycline-induced black pigmentation of the gland.
    Taurog A, Dorris ML, Doerge DR.
    Thyroid; 1996 Jun 01; 6(3):211-9. PubMed ID: 8837329
    [Abstract] [Full Text] [Related]

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