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427 related items for PubMed ID: 23968485
1. Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity. Surivet JP, Zumbrunn C, Rueedi G, Hubschwerlen C, Bur D, Bruyère T, Locher H, Ritz D, Keck W, Seiler P, Kohl C, Gauvin JC, Mirre A, Kaegi V, Dos Santos M, Gaertner M, Delers J, Enderlin-Paput M, Boehme M. J Med Chem; 2013 Sep 26; 56(18):7396-415. PubMed ID: 23968485 [Abstract] [Full Text] [Related]
8. Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects. Ibrahim NM, Fahim SH, Hassan M, Farag AE, Georgey HH. Eur J Med Chem; 2022 Jan 15; 228():114021. PubMed ID: 34871841 [Abstract] [Full Text] [Related]
12. Dual inhibition of Staphylococcus aureus DNA gyrase and topoisomerase IV activity by phenylalanine-derived (Z)-5-arylmethylidene rhodanines. Werner MM, Patel BA, Talele TT, Ashby CR, Li Z, Zauhar RJ. Bioorg Med Chem; 2015 Sep 15; 23(18):6125-37. PubMed ID: 26320664 [Abstract] [Full Text] [Related]
14. Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2). Singh SB, Kaelin DE, Wu J, Miesel L, Tan CM, Black T, Nargund R, Meinke PT, Olsen DB, Lagrutta A, Lu J, Patel S, Rickert KW, Smith RF, Soisson S, Sherer E, Joyce LA, Wei C, Peng X, Wang X, Fukuda H, Kishii R, Takei M, Takano H, Shibasaki M, Yajima M, Nishimura A, Shibata T, Fukuda Y. Bioorg Med Chem Lett; 2015 May 01; 25(9):1831-5. PubMed ID: 25851938 [Abstract] [Full Text] [Related]
15. Structure activity relationship of C-2 ether substituted 1,5-naphthyridine analogs of oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents (Part-5). Singh SB, Kaelin DE, Meinke PT, Wu J, Miesel L, Tan CM, Olsen DB, Lagrutta A, Fukuda H, Kishii R, Takei M, Takeuchi T, Takano H, Ohata K, Kurasaki H, Nishimura A, Shibata T, Fukuda Y. Bioorg Med Chem Lett; 2015 Sep 01; 25(17):3630-5. PubMed ID: 26152426 [Abstract] [Full Text] [Related]
18. In Vitro and In Vivo Characterization of the Novel Oxabicyclooctane-Linked Bacterial Topoisomerase Inhibitor AM-8722, a Selective, Potent Inhibitor of Bacterial DNA Gyrase. Tan CM, Gill CJ, Wu J, Toussaint N, Yin J, Tsuchiya T, Garlisi CG, Kaelin D, Meinke PT, Miesel L, Olsen DB, Lagrutta A, Fukuda H, Kishii R, Takei M, Oohata K, Takeuchi T, Shibue T, Takano H, Nishimura A, Fukuda Y, Singh SB. Antimicrob Agents Chemother; 2016 Aug 01; 60(8):4830-9. PubMed ID: 27246784 [Abstract] [Full Text] [Related]