These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

565 related items for PubMed ID: 23977270

  • 1. Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor.
    Costa B, Bendinelli S, Gabelloni P, Da Pozzo E, Daniele S, Scatena F, Vanacore R, Campiglia P, Bertamino A, Gomez-Monterrey I, Sorriento D, Del Giudice C, Iaccarino G, Novellino E, Martini C.
    PLoS One; 2013; 8(8):e72281. PubMed ID: 23977270
    [Abstract] [Full Text] [Related]

  • 2. CXCR4 antagonism sensitizes cancer cells to novel indole-based MDM2/4 inhibitors in glioblastoma multiforme.
    Daniele S, La Pietra V, Piccarducci R, Pietrobono D, Cavallini C, D'Amore VM, Cerofolini L, Giuntini S, Russomanno P, Puxeddu M, Nalli M, Pedrini M, Fragai M, Luchinat C, Novellino E, Taliani S, La Regina G, Silvestri R, Martini C, Marinelli L.
    Eur J Pharmacol; 2021 Apr 15; 897():173936. PubMed ID: 33581134
    [Abstract] [Full Text] [Related]

  • 3. Targeted Brain Tumor Therapy by Inhibiting the MDM2 Oncogene: In Vitro and In Vivo Antitumor Activity and Mechanism of Action.
    Punganuru SR, Artula V, Zhao W, Rajaei M, Deokar H, Zhang R, Buolamwini JK, Srivenugopal KS, Wang W.
    Cells; 2020 Jul 01; 9(7):. PubMed ID: 32630235
    [Abstract] [Full Text] [Related]

  • 4. A stapled peptide antagonist of MDM2 carried by polymeric micelles sensitizes glioblastoma to temozolomide treatment through p53 activation.
    Chen X, Tai L, Gao J, Qian J, Zhang M, Li B, Xie C, Lu L, Lu W, Lu W.
    J Control Release; 2015 Nov 28; 218():29-35. PubMed ID: 26428461
    [Abstract] [Full Text] [Related]

  • 5. Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells.
    Daniele S, Costa B, Zappelli E, Da Pozzo E, Sestito S, Nesi G, Campiglia P, Marinelli L, Novellino E, Rapposelli S, Martini C.
    Sci Rep; 2015 Apr 21; 5():9956. PubMed ID: 25898313
    [Abstract] [Full Text] [Related]

  • 6.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 7.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 8.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 9. Spiro-oxindole derivative 5-chloro-4',5'-diphenyl-3'-(4-(2-(piperidin-1-yl) ethoxy) benzoyl) spiro[indoline-3,2'-pyrrolidin]-2-one triggers apoptosis in breast cancer cells via restoration of p53 function.
    Saxena R, Gupta G, Manohar M, Debnath U, Popli P, Prabhakar YS, Konwar R, Kumar S, Kumar A, Dwivedi A.
    Int J Biochem Cell Biol; 2016 Jan 21; 70():105-17. PubMed ID: 26556313
    [Abstract] [Full Text] [Related]

  • 10. Efficacy of the MDM2 Inhibitor SAR405838 in Glioblastoma Is Limited by Poor Distribution Across the Blood-Brain Barrier.
    Kim M, Ma DJ, Calligaris D, Zhang S, Feathers RW, Vaubel RA, Meaux I, Mladek AC, Parrish KE, Jin F, Barriere C, Debussche L, Watters J, Tian S, Decker PA, Eckel-Passow JE, Kitange GJ, Johnson AJ, Parney IF, Anastasiadis PZ, Agar NYR, Elmquist WF, Sarkaria JN.
    Mol Cancer Ther; 2018 Sep 21; 17(9):1893-1901. PubMed ID: 29970480
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of MDM2 Re-Sensitizes Rapamycin Resistant Renal Cancer Cells via the Activation of p53.
    Tian X, Dai S, Sun J, Jiang S, Sui C, Meng F, Li Y, Fu L, Jiang T, Wang Y, Su J, Jiang Y.
    Cell Physiol Biochem; 2016 Sep 21; 39(5):2088-2098. PubMed ID: 27825169
    [Abstract] [Full Text] [Related]

  • 12. Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma.
    Lu J, Guan S, Zhao Y, Yu Y, Wang Y, Shi Y, Mao X, Yang KL, Sun W, Xu X, Yi JS, Yang T, Yang J, Nuchtern JG.
    Oncotarget; 2016 Dec 13; 7(50):82757-82769. PubMed ID: 27764791
    [Abstract] [Full Text] [Related]

  • 13. Reactivation of p53 by novel MDM2 inhibitors: implications for pancreatic cancer therapy.
    Azmi AS, Philip PA, Aboukameel A, Wang Z, Banerjee S, Zafar SF, Goustin AS, Almhanna K, Yang D, Sarkar FH, Mohammad RM.
    Curr Cancer Drug Targets; 2010 May 13; 10(3):319-31. PubMed ID: 20370686
    [Abstract] [Full Text] [Related]

  • 14. SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression.
    Wang S, Sun W, Zhao Y, McEachern D, Meaux I, Barrière C, Stuckey JA, Meagher JL, Bai L, Liu L, Hoffman-Luca CG, Lu J, Shangary S, Yu S, Bernard D, Aguilar A, Dos-Santos O, Besret L, Guerif S, Pannier P, Gorge-Bernat D, Debussche L.
    Cancer Res; 2014 Oct 15; 74(20):5855-65. PubMed ID: 25145672
    [Abstract] [Full Text] [Related]

  • 15. Neuropilin-1 enhances temozolomide resistance in glioblastoma via the STAT1/p53/p21 axis.
    Huang P, Zhang L, Wang H, Dou C, Ju H, Yue P, Ren J.
    Neuropathology; 2024 Aug 15; 44(4):319-330. PubMed ID: 38448392
    [Abstract] [Full Text] [Related]

  • 16. Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice.
    Wang W, Qin JJ, Voruganti S, Wang MH, Sharma H, Patil S, Zhou J, Wang H, Mukhopadhyay D, Buolamwini JK, Zhang R.
    Gastroenterology; 2014 Oct 15; 147(4):893-902.e2. PubMed ID: 25016295
    [Abstract] [Full Text] [Related]

  • 17. Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer.
    Shangary S, Ding K, Qiu S, Nikolovska-Coleska Z, Bauer JA, Liu M, Wang G, Lu Y, McEachern D, Bernard D, Bradford CR, Carey TE, Wang S.
    Mol Cancer Ther; 2008 Jun 15; 7(6):1533-42. PubMed ID: 18566224
    [Abstract] [Full Text] [Related]

  • 18. NBM-BMX, an HDAC8 Inhibitor, Overcomes Temozolomide Resistance in Glioblastoma Multiforme by Downregulating the β-Catenin/c-Myc/SOX2 Pathway and Upregulating p53-Mediated MGMT Inhibition.
    Tsai CY, Ko HJ, Chiou SJ, Lai YL, Hou CC, Javaria T, Huang ZY, Cheng TS, Hsu TI, Chuang JY, Kwan AL, Chuang TH, Huang CF, Loh JK, Hong YR.
    Int J Mol Sci; 2021 May 31; 22(11):. PubMed ID: 34072831
    [Abstract] [Full Text] [Related]

  • 19. BI-907828, a novel potent MDM2 inhibitor, inhibits glioblastoma brain tumor stem cells in vitro and prolongs survival in orthotopic xenograft mouse models.
    Hao X, Bahia RK, Cseh O, Bozek DA, Blake S, Rinnenthal J, Weyer-Czernilofsky U, Rudolph D, Artee Luchman H.
    Neuro Oncol; 2023 May 04; 25(5):913-926. PubMed ID: 36521007
    [Abstract] [Full Text] [Related]

  • 20. Long lasting MDM2/Translocator protein modulator: a new strategy for irreversible apoptosis of human glioblastoma cells.
    Daniele S, Barresi E, Zappelli E, Marinelli L, Novellino E, Da Settimo F, Taliani S, Trincavelli ML, Martini C.
    Oncotarget; 2016 Feb 16; 7(7):7866-84. PubMed ID: 26761214
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 29.