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106 related items for PubMed ID: 23978569

  • 1. Differential inhibition of signaling pathways by two new imidazo-pyrazoles molecules in fMLF-OMe- and IL8-stimulated human neutrophil.
    Selvatici R, Brullo C, Bruno O, Spisani S.
    Eur J Pharmacol; 2013 Oct 15; 718(1-3):428-34. PubMed ID: 23978569
    [Abstract] [Full Text] [Related]

  • 2. N-Aryl-2-phenyl-2,3-dihydro-imidazo[1,2-b]pyrazole-1-carboxamides 7-substituted strongly inhibiting both fMLP-OMe- and IL-8-induced human neutrophil chemotaxis.
    Brullo C, Spisani S, Selvatici R, Bruno O.
    Eur J Med Chem; 2012 Jan 15; 47(1):573-9. PubMed ID: 22152986
    [Abstract] [Full Text] [Related]

  • 3. 1-Methyl and 1-(2-hydroxyalkyl)-5-(3-alkyl/cycloalkyl/phenyl/naphthylureido)-1H-pyrazole-4-carboxylic acid ethyl esters as potent human neutrophil chemotaxis inhibitors.
    Bruno O, Brullo C, Bondavalli F, Schenone S, Spisani S, Falzarano MS, Varani K, Barocelli E, Ballabeni V, Giorgio C, Tognolini M.
    Bioorg Med Chem; 2009 May 01; 17(9):3379-87. PubMed ID: 19362486
    [Abstract] [Full Text] [Related]

  • 4. Isopeptide bonds in chemotactic tripeptides. Synthesis and activity of lysine-containing fMLF analogs.
    Pagani Zecchini G, Nalli M, Mollica A, Lucente G, Paglialunga Paradisi M, Spisani S.
    J Pept Res; 2002 Jun 01; 59(6):283-91. PubMed ID: 12010519
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of N-pyrazolyl-N'-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis.
    Bruno O, Brullo C, Bondavalli F, Schenone S, Ranise A, Arduino N, Bertolotto MB, Montecucco F, Ottonello L, Dallegri F, Tognolini M, Ballabeni V, Bertoni S, Barocelli E.
    J Med Chem; 2007 Jul 26; 50(15):3618-26. PubMed ID: 17608466
    [Abstract] [Full Text] [Related]

  • 6. Oleuropein and hydroxytyrosol inhibit the N-formyl-methionyl-leucyl-phenylalanine-induced neutrophil degranulation and chemotaxis via AKT, p38, and ERK1/2 MAP-Kinase inhibition.
    Bedouhene S, Moulti-Mati F, Dang PM, El-Benna J.
    Inflammopharmacology; 2017 Dec 26; 25(6):673-680. PubMed ID: 28711992
    [Abstract] [Full Text] [Related]

  • 7. Novel chemotactic For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on met residue replacement by 4-amino-proline scaffold: synthesis and bioactivity.
    Torino D, Mollica A, Pinnen F, Feliciani F, Spisani S, Lucente G.
    Bioorg Med Chem; 2009 Jan 01; 17(1):251-9. PubMed ID: 19081258
    [Abstract] [Full Text] [Related]

  • 8. 2-Phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole derivatives: new potent inhibitors of fMLP-induced neutrophil chemotaxis.
    Bruno O, Brullo C, Bondavalli F, Ranise A, Schenone S, Falzarano MS, Varani K, Spisani S.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3696-701. PubMed ID: 17475488
    [Abstract] [Full Text] [Related]

  • 9. The importance of the peptide bond at position 2 in HCO-Met-Leu-Phe-OMe analogues as shown by studies on human neutrophils.
    Cavicchioni G, Breveglieri A, Boggian M, Vertuani G, Reali E, Spisani S.
    J Pept Sci; 1996 Jul 01; 2(3):135-40. PubMed ID: 9231322
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of new active For-Met-Leu-Phe-OMe analogues containing para-substituted Phe residues.
    Mollica A, Feliciani F, Stefanucci A, Costante R, Lucente G, Pinnen F, Notaristefano D, Spisani S.
    J Pept Sci; 2012 Jun 01; 18(6):418-26. PubMed ID: 22528501
    [Abstract] [Full Text] [Related]

  • 11. Regulation of VASP serine 157 phosphorylation in human neutrophils after stimulation by a chemoattractant.
    Eckert RE, Jones SL.
    J Leukoc Biol; 2007 Nov 01; 82(5):1311-21. PubMed ID: 17684042
    [Abstract] [Full Text] [Related]

  • 12. PKC-delta controls the fMLF-induced overproduction of superoxide by neutrophils.
    Matron C, Chakravarti A, Allaeys I, Poubelle PE.
    Free Radic Biol Med; 2010 Jan 15; 48(2):207-15. PubMed ID: 19854263
    [Abstract] [Full Text] [Related]

  • 13. The mechanism for activation of the neutrophil NADPH-oxidase by the peptides formyl-Met-Leu-Phe and Trp-Lys-Tyr-Met-Val-Met differs from that for interleukin-8.
    Fu H, Bylund J, Karlsson A, Pellmé S, Dahlgren C.
    Immunology; 2004 Jun 15; 112(2):201-10. PubMed ID: 15147563
    [Abstract] [Full Text] [Related]

  • 14. Phospholipase D-dependent and -independent p38MAPK activation pathways are required for superoxide production and chemotactic induction, respectively, in rat neutrophils stimulated by fMLP.
    Azuma Y, Kosaka K, Kashimata M.
    Eur J Pharmacol; 2007 Jul 30; 568(1-3):260-8. PubMed ID: 17560994
    [Abstract] [Full Text] [Related]

  • 15. Human neutrophil Fc gamma RIIIB and formyl peptide receptors are functionally linked during formyl-methionyl-leucyl-phenylalanine-induced chemotaxis.
    Kew RR, Grimaldi CM, Furie MB, Fleit HB.
    J Immunol; 1992 Aug 01; 149(3):989-97. PubMed ID: 1321856
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and bioactivity of chemotactic tetrapeptides: fMLF-OMe analogues incorporating spacer aminoacids at the lateral positions.
    Lucente G, Giordano C, Sansone A, Torino D, Spisani S.
    Amino Acids; 2009 Jul 01; 37(2):285-95. PubMed ID: 18636221
    [Abstract] [Full Text] [Related]

  • 17. Biological activity of for-Met-Leu-Phe-OMe analogs: relevant substitutions specifically trigger killing mechanisms in human neutrophils.
    Cavicchioni G, Fraulini A, Turchetti M, Varani K, Falzarano S, Pavan B, Spisani S.
    Eur J Pharmacol; 2005 Apr 04; 512(1):1-8. PubMed ID: 15814083
    [Abstract] [Full Text] [Related]

  • 18. Selective inhibition of human neutrophil chemotaxis to N-formyl-methionyl-leucyl-phenylalanine by sulfones.
    Harvath L, Yancey KB, Katz SI.
    J Immunol; 1986 Aug 15; 137(4):1305-11. PubMed ID: 3016092
    [Abstract] [Full Text] [Related]

  • 19. Properties of a novel chemotactic esapeptide, an analogue of the prototypical N-formylmethionyl peptide.
    Cavicchioni G, Turchetti M, Varani K, Falzarano S, Spisani S.
    Bioorg Chem; 2003 Aug 15; 31(4):322-30. PubMed ID: 12877881
    [Abstract] [Full Text] [Related]

  • 20. New chemotactic peptide analogs with high biological activity for human neutrophils.
    Spisani S, Traniello S, Giuliani AL, Torrini I, Pagani Zecchini G, Paglialunga Paradisi M, Gavuzzo E, Mazza F, Pochetti G, Lucente G.
    Biochem Int; 1992 May 15; 26(6):1125-35. PubMed ID: 1321622
    [Abstract] [Full Text] [Related]


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