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441 related items for PubMed ID: 23982736

  • 1. Low concentration of metformin induces a p53-dependent senescence in hepatoma cells via activation of the AMPK pathway.
    Yi G, He Z, Zhou X, Xian L, Yuan T, Jia X, Hong J, He L, Liu J.
    Int J Oncol; 2013 Nov; 43(5):1503-10. PubMed ID: 23982736
    [Abstract] [Full Text] [Related]

  • 2. Negative regulation of Sirtuin 1 by AMP-activated protein kinase promotes metformin-induced senescence in hepatocellular carcinoma xenografts.
    Zhou X, Chen J, Chen L, Feng X, Liu Z, Hu L, Zeng Z, Jia X, Liang M, Shi B, Yi G, Liu J.
    Cancer Lett; 2017 Dec 28; 411():1-11. PubMed ID: 28964787
    [Abstract] [Full Text] [Related]

  • 3. EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells.
    Huang CH, Tsai SJ, Wang YJ, Pan MH, Kao JY, Way TD.
    Mol Nutr Food Res; 2009 Sep 28; 53(9):1156-65. PubMed ID: 19662644
    [Abstract] [Full Text] [Related]

  • 4. Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma.
    Zheng L, Yang W, Wu F, Wang C, Yu L, Tang L, Qiu B, Li Y, Guo L, Wu M, Feng G, Zou D, Wang H.
    Clin Cancer Res; 2013 Oct 01; 19(19):5372-80. PubMed ID: 23942093
    [Abstract] [Full Text] [Related]

  • 5. Metformin decreases hepatocellular carcinoma risk in a dose-dependent manner: population-based and in vitro studies.
    Chen HP, Shieh JJ, Chang CC, Chen TT, Lin JT, Wu MS, Lin JH, Wu CY.
    Gut; 2013 Apr 01; 62(4):606-15. PubMed ID: 22773548
    [Abstract] [Full Text] [Related]

  • 6. AMPK induces vascular smooth muscle cell senescence via LKB1 dependent pathway.
    Sung JY, Woo CH, Kang YJ, Lee KY, Choi HC.
    Biochem Biophys Res Commun; 2011 Sep 16; 413(1):143-8. PubMed ID: 21872575
    [Abstract] [Full Text] [Related]

  • 7. Negative regulation of transcription factor FoxM1 by p53 enhances oxaliplatin-induced senescence in hepatocellular carcinoma.
    Qu K, Xu X, Liu C, Wu Q, Wei J, Meng F, Zhou L, Wang Z, Lei L, Liu P.
    Cancer Lett; 2013 Apr 30; 331(1):105-14. PubMed ID: 23262037
    [Abstract] [Full Text] [Related]

  • 8. Metformin limits ceramide-induced senescence in C2C12 myoblasts.
    Jadhav KS, Dungan CM, Williamson DL.
    Mech Ageing Dev; 2013 Apr 30; 134(11-12):548-59. PubMed ID: 24269881
    [Abstract] [Full Text] [Related]

  • 9. Hemistepsin A Inhibits Cell Proliferation and Induces G0/G1-Phase Arrest, Cellular Senescence and Apoptosis Via the AMPK and p53/p21 Signals in Human Hepatocellular Carcinoma.
    Baek SY, Hwang UW, Suk HY, Kim YW.
    Biomolecules; 2020 May 04; 10(5):. PubMed ID: 32375410
    [Abstract] [Full Text] [Related]

  • 10. PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27Kip1 axis.
    Tuo L, Xiang J, Pan X, Hu J, Tang H, Liang L, Xia J, Hu Y, Zhang W, Huang A, Wang K, Tang N.
    J Exp Clin Cancer Res; 2019 Feb 04; 38(1):50. PubMed ID: 30717766
    [Abstract] [Full Text] [Related]

  • 11. Cisplatin induces cell cycle arrest and senescence via upregulating P53 and P21 expression in HepG2 cells.
    Qu K, Lin T, Wei J, Meng F, Wang Z, Huang Z, Wan Y, Song S, Liu S, Chang H, Dong Y, Liu C.
    Nan Fang Yi Ke Da Xue Xue Bao; 2013 Sep 04; 33(9):1253-9. PubMed ID: 24067199
    [Abstract] [Full Text] [Related]

  • 12. SIRT1 regulates oncogenesis via a mutant p53-dependent pathway in hepatocellular carcinoma.
    Zhang ZY, Hong D, Nam SH, Kim JM, Paik YH, Joh JW, Kwon CH, Park JB, Choi GS, Jang KY, Park CK, Kim SJ.
    J Hepatol; 2015 Jan 04; 62(1):121-30. PubMed ID: 25131770
    [Abstract] [Full Text] [Related]

  • 13. Expression of hepaCAM is downregulated in cancers and induces senescence-like growth arrest via a p53/p21-dependent pathway in human breast cancer cells.
    Moh MC, Zhang T, Lee LH, Shen S.
    Carcinogenesis; 2008 Dec 04; 29(12):2298-305. PubMed ID: 18845560
    [Abstract] [Full Text] [Related]

  • 14. Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence.
    Min LJ, Mogi M, Iwanami J, Li JM, Sakata A, Fujita T, Tsukuda K, Iwai M, Horiuchi M.
    Cardiovasc Res; 2007 Dec 01; 76(3):506-16. PubMed ID: 17706954
    [Abstract] [Full Text] [Related]

  • 15. Regulation of SIRT1/AMPK axis is critically involved in gallotannin-induced senescence and impaired autophagy leading to cell death in hepatocellular carcinoma cells.
    Kwon HY, Kim JH, Kim B, Srivastava SK, Kim SH.
    Arch Toxicol; 2018 Jan 01; 92(1):241-257. PubMed ID: 28676953
    [Abstract] [Full Text] [Related]

  • 16. Adiponectin and metformin additively attenuate IL1β-induced malignant potential of colon cancer.
    Moon HS, Mantzoros CS.
    Endocr Relat Cancer; 2013 Dec 01; 20(6):849-59. PubMed ID: 24157941
    [Abstract] [Full Text] [Related]

  • 17. Induction of p53-independent p21 during ceramide-induced G1 arrest in human hepatocarcinoma cells.
    Kim WH, Kang KH, Kim MY, Choi KH.
    Biochem Cell Biol; 2000 Dec 01; 78(2):127-35. PubMed ID: 10874474
    [Abstract] [Full Text] [Related]

  • 18. Metformin inhibits growth of eutopic stromal cells from adenomyotic endometrium via AMPK activation and subsequent inhibition of AKT phosphorylation: a possible role in the treatment of adenomyosis.
    Xue J, Zhang H, Liu W, Liu M, Shi M, Wen Z, Li C.
    Reproduction; 2013 Oct 01; 146(4):397-406. PubMed ID: 23904524
    [Abstract] [Full Text] [Related]

  • 19. Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth.
    Rocha GZ, Dias MM, Ropelle ER, Osório-Costa F, Rossato FA, Vercesi AE, Saad MJ, Carvalheira JB.
    Clin Cancer Res; 2011 Jun 15; 17(12):3993-4005. PubMed ID: 21543517
    [Abstract] [Full Text] [Related]

  • 20. COH-203, a novel microtubule inhibitor, exhibits potent anti-tumor activity via p53-dependent senescence in hepatocellular carcinoma.
    Qi H, Zuo DY, Bai ZS, Xu JW, Li ZQ, Shen QR, Wang ZW, Zhang WG, Wu YL.
    Biochem Biophys Res Commun; 2014 Dec 12; 455(3-4):262-8. PubMed ID: 25449279
    [Abstract] [Full Text] [Related]


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