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Journal Abstract Search

404 related items for PubMed ID: 23986435

  • 1.
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  • 2. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.
    J Biol Chem; 2011 Mar 18; 286(11):9382-92. PubMed ID: 21148306
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  • 3. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J, Huang K, O'Neill KL, Pang X, Luo X.
    Cell Death Dis; 2016 Jun 16; 7(6):e2266. PubMed ID: 27310874
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  • 4. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
    Du H, Wolf J, Schafer B, Moldoveanu T, Chipuk JE, Kuwana T.
    J Biol Chem; 2011 Jan 07; 286(1):491-501. PubMed ID: 21041309
    [Abstract] [Full Text] [Related]

  • 5. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
    Rahmani M, Aust MM, Attkisson E, Williams DC, Ferreira-Gonzalez A, Grant S.
    Cancer Res; 2013 Feb 15; 73(4):1340-51. PubMed ID: 23243017
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  • 7. Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis.
    Rajan S, Choi M, Baek K, Yoon HS.
    Proteins; 2015 Jul 15; 83(7):1262-72. PubMed ID: 25907960
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  • 8. Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver.
    Hikita H, Takehara T, Shimizu S, Kodama T, Li W, Miyagi T, Hosui A, Ishida H, Ohkawa K, Kanto T, Hiramatsu N, Yin XM, Hennighausen L, Tatsumi T, Hayashi N.
    Hepatology; 2009 Oct 15; 50(4):1217-26. PubMed ID: 19676108
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  • 9. BH3-only protein bid participates in the Bcl-2 network in healthy liver cells.
    Hikita H, Takehara T, Kodama T, Shimizu S, Hosui A, Miyagi T, Tatsumi T, Ishida H, Ohkawa K, Li W, Kanto T, Hiramatsu N, Hennighausen L, Yin XM, Hayashi N.
    Hepatology; 2009 Dec 15; 50(6):1972-80. PubMed ID: 19839062
    [Abstract] [Full Text] [Related]

  • 10. FTY720 induces apoptosis of chronic myelogenous leukemia cells via dual activation of BIM and BID and overcomes various types of resistance to tyrosine kinase inhibitors.
    Kiyota M, Kuroda J, Yamamoto-Sugitani M, Shimura Y, Nakayama R, Nagoshi H, Mizutani S, Chinen Y, Sasaki N, Sakamoto N, Kobayashi T, Matsumoto Y, Horiike S, Taniwaki M.
    Apoptosis; 2013 Nov 15; 18(11):1437-1446. PubMed ID: 23851982
    [Abstract] [Full Text] [Related]

  • 11. BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets.
    Kodama T, Takehara T, Hikita H, Shimizu S, Shigekawa M, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Kanto T, Hiramatsu N, Yin XM, Hayashi N.
    J Biol Chem; 2011 Apr 22; 286(16):13905-13. PubMed ID: 21367852
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  • 13. Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells.
    Aranovich A, Liu Q, Collins T, Geng F, Dixit S, Leber B, Andrews DW.
    Mol Cell; 2012 Mar 30; 45(6):754-63. PubMed ID: 22464442
    [Abstract] [Full Text] [Related]

  • 14. BH3-only protein BIM mediates heat shock-induced apoptosis.
    Mahajan IM, Chen MD, Muro I, Robertson JD, Wright CW, Bratton SB.
    PLoS One; 2014 Mar 30; 9(1):e84388. PubMed ID: 24427286
    [Abstract] [Full Text] [Related]

  • 15. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.
    Huang K, O'Neill KL, Li J, Zhou W, Han N, Pang X, Wu W, Struble L, Borgstahl G, Liu Z, Zhang L, Luo X.
    Cell Res; 2019 Nov 30; 29(11):942-952. PubMed ID: 31551537
    [Abstract] [Full Text] [Related]

  • 16. Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim.
    Jabbour AM, Heraud JE, Daunt CP, Kaufmann T, Sandow J, O'Reilly LA, Callus BA, Lopez A, Strasser A, Vaux DL, Ekert PG.
    Cell Death Differ; 2009 Apr 30; 16(4):555-63. PubMed ID: 19079139
    [Abstract] [Full Text] [Related]

  • 17. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
    Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, Czabotar PE, Ierino H, Lee EF, Fairlie WD, Bouillet P, Strasser A, Kluck RM, Adams JM, Huang DC.
    Science; 2007 Feb 09; 315(5813):856-9. PubMed ID: 17289999
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  • 18. Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax.
    Shamas-Din A, Bindner S, Chi X, Leber B, Andrews DW, Fradin C.
    Biochem J; 2015 May 01; 467(3):495-505. PubMed ID: 25714678
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