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498 related items for PubMed ID: 23994215

  • 1. Cellular NAD depletion and decline of SIRT1 activity play critical roles in PARP-1-mediated acute epileptic neuronal death in vitro.
    Wang S, Yang X, Lin Y, Qiu X, Li H, Zhao X, Cao L, Liu X, Pang Y, Wang X, Chi Z.
    Brain Res; 2013 Oct 16; 1535():14-23. PubMed ID: 23994215
    [Abstract] [Full Text] [Related]

  • 2. Poly(ADP-ribose) polymerase inhibition protects epileptic hippocampal neurons from apoptosis via suppressing Akt-mediated apoptosis-inducing factor translocation in vitro.
    Yang X, Wang S, Lin Y, Han Y, Qiu X, Zhao X, Cao L, Wang X, Chi Z.
    Neuroscience; 2013 Feb 12; 231():353-62. PubMed ID: 23201256
    [Abstract] [Full Text] [Related]

  • 3. Activation of cell death mediated by apoptosis-inducing factor due to the absence of poly(ADP-ribose) glycohydrolase.
    Zhou Y, Feng X, Koh DW.
    Biochemistry; 2011 Apr 12; 50(14):2850-9. PubMed ID: 21366272
    [Abstract] [Full Text] [Related]

  • 4. Poly(ADP-ribose) polymerase-1 causes mitochondrial damage and neuron death mediated by Bnip3.
    Lu P, Kamboj A, Gibson SB, Anderson CM.
    J Neurosci; 2014 Nov 26; 34(48):15975-87. PubMed ID: 25429139
    [Abstract] [Full Text] [Related]

  • 5. Protective effect of nicotinamide against poly(ADP-ribose) polymerase-1-mediated astrocyte death depends on its transporter-mediated uptake.
    Suzuki E, Okuda H, Nishida K, Fujimoto S, Nagasawa K.
    Life Sci; 2010 Apr 24; 86(17-18):676-82. PubMed ID: 20188745
    [Abstract] [Full Text] [Related]

  • 6. Caspase inhibition augments Dichlorvos-induced dopaminergic neuronal cell death by increasing ROS production and PARP1 activation.
    Wani WY, Sunkaria A, Sharma DR, Kandimalla RJ, Kaushal A, Gerace E, Chiarugi A, Gill KD.
    Neuroscience; 2014 Jan 31; 258():1-15. PubMed ID: 24231740
    [Abstract] [Full Text] [Related]

  • 7. Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition.
    Kondo K, Obitsu S, Ohta S, Matsunami K, Otsuka H, Teshima R.
    J Biol Chem; 2010 Apr 23; 285(17):13079-91. PubMed ID: 20177052
    [Abstract] [Full Text] [Related]

  • 8. NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death.
    Alano CC, Garnier P, Ying W, Higashi Y, Kauppinen TM, Swanson RA.
    J Neurosci; 2010 Feb 24; 30(8):2967-78. PubMed ID: 20181594
    [Abstract] [Full Text] [Related]

  • 9. Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.
    Endres M, Wang ZQ, Namura S, Waeber C, Moskowitz MA.
    J Cereb Blood Flow Metab; 1997 Nov 24; 17(11):1143-51. PubMed ID: 9390645
    [Abstract] [Full Text] [Related]

  • 10. Caspase-independent cell death by arsenic trioxide in human cervical cancer cells: reactive oxygen species-mediated poly(ADP-ribose) polymerase-1 activation signals apoptosis-inducing factor release from mitochondria.
    Kang YH, Yi MJ, Kim MJ, Park MT, Bae S, Kang CM, Cho CK, Park IC, Park MJ, Rhee CH, Hong SI, Chung HY, Lee YS, Lee SJ.
    Cancer Res; 2004 Dec 15; 64(24):8960-7. PubMed ID: 15604259
    [Abstract] [Full Text] [Related]

  • 11. Beta-amyloid activates PARP causing astrocytic metabolic failure and neuronal death.
    Abeti R, Abramov AY, Duchen MR.
    Brain; 2011 Jun 15; 134(Pt 6):1658-72. PubMed ID: 21616968
    [Abstract] [Full Text] [Related]

  • 12. Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition.
    Alano CC, Ying W, Swanson RA.
    J Biol Chem; 2004 Apr 30; 279(18):18895-902. PubMed ID: 14960594
    [Abstract] [Full Text] [Related]

  • 13. Simultaneous cell death and upregulation of poly(ADP-ribose) polymerase-1 expression in early postnatal mouse retina.
    Martín-Oliva D, Ferrer-Martín RM, Santos AM, Carrasco MC, Sierra A, Marín-Teva JL, Calvente R, Navascués J, Cuadros MA.
    Invest Ophthalmol Vis Sci; 2011 Sep 27; 52(10):7445-54. PubMed ID: 21705688
    [Abstract] [Full Text] [Related]

  • 14. Involvement of independent mechanism upon poly(ADP-ribose) polymerase (PARP) activation in methylmercury cytotoxicity in rat cerebellar granule cell culture.
    Sakaue M, Mori N, Okazaki M, Ishii M, Inagaki Y, Iino Y, Miyahara K, Yamamoto M, Kumagai T, Hara S, Yamamoto M, Arishima K.
    J Neurosci Res; 2008 Nov 15; 86(15):3427-34. PubMed ID: 18627028
    [Abstract] [Full Text] [Related]

  • 15. Glucose deprivation converts poly(ADP-ribose) polymerase-1 hyperactivation into a transient energy-producing process.
    Buonvicino D, Formentini L, Cipriani G, Chiarugi A.
    J Biol Chem; 2013 Dec 20; 288(51):36530-7. PubMed ID: 24194524
    [Abstract] [Full Text] [Related]

  • 16. Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain.
    Poitras MF, Koh DW, Yu SW, Andrabi SA, Mandir AS, Poirier GG, Dawson VL, Dawson TM.
    Neuroscience; 2007 Aug 10; 148(1):198-211. PubMed ID: 17640816
    [Abstract] [Full Text] [Related]

  • 17. A novel and potent poly(ADP-ribose) polymerase-1 inhibitor, FR247304 (5-chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), attenuates neuronal damage in in vitro and in vivo models of cerebral ischemia.
    Iwashita A, Tojo N, Matsuura S, Yamazaki S, Kamijo K, Ishida J, Yamamoto H, Hattori K, Matsuoka N, Mutoh S.
    J Pharmacol Exp Ther; 2004 Aug 10; 310(2):425-36. PubMed ID: 15075382
    [Abstract] [Full Text] [Related]

  • 18. Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos).
    Wang Y, Kim NS, Haince JF, Kang HC, David KK, Andrabi SA, Poirier GG, Dawson VL, Dawson TM.
    Sci Signal; 2011 Apr 05; 4(167):ra20. PubMed ID: 21467298
    [Abstract] [Full Text] [Related]

  • 19. Mitochondrial Dysfunction Mediated by Poly(ADP-Ribose) Polymerase-1 Activation Contributes to Hippocampal Neuronal Damage Following Status Epilepticus.
    Lai YC, Baker JS, Donti T, Graham BH, Craigen WJ, Anderson AE.
    Int J Mol Sci; 2017 Jul 12; 18(7):. PubMed ID: 28704930
    [Abstract] [Full Text] [Related]

  • 20. PARP-1 inhibition does not restore oxidant-mediated reduction in SIRT1 activity.
    Caito S, Hwang JW, Chung S, Yao H, Sundar IK, Rahman I.
    Biochem Biophys Res Commun; 2010 Feb 12; 392(3):264-70. PubMed ID: 20060806
    [Abstract] [Full Text] [Related]

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