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670 related items for PubMed ID: 24008870

  • 1. Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage.
    Völkers M, Konstandin MH, Doroudgar S, Toko H, Quijada P, Din S, Joyo A, Ornelas L, Samse K, Thuerauf DJ, Gude N, Glembotski CC, Sussman MA.
    Circulation; 2013 Nov 05; 128(19):2132-44. PubMed ID: 24008870
    [Abstract] [Full Text] [Related]

  • 2. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
    Le Bacquer O, Queniat G, Gmyr V, Kerr-Conte J, Lefebvre B, Pattou F.
    J Endocrinol; 2013 Jan 05; 216(1):21-9. PubMed ID: 23092880
    [Abstract] [Full Text] [Related]

  • 3. Targeting of mTORC2 may have advantages over selective targeting of mTORC1 in the treatment of malignant pheochromocytoma.
    Zhang X, Wang X, Xu T, Zhong S, Shen Z.
    Tumour Biol; 2015 Jul 05; 36(7):5273-81. PubMed ID: 25666752
    [Abstract] [Full Text] [Related]

  • 4. Synergistic Effects between mTOR Complex 1/2 and Glycolysis Inhibitors in Non-Small-Cell Lung Carcinoma Cells.
    Jiang S, Zou Z, Nie P, Wen R, Xiao Y, Tang J.
    PLoS One; 2015 Jul 05; 10(7):e0132880. PubMed ID: 26176608
    [Abstract] [Full Text] [Related]

  • 5. Hypoxia Increases IGFBP-1 Phosphorylation Mediated by mTOR Inhibition.
    Damerill I, Biggar KK, Abu Shehab M, Li SS, Jansson T, Gupta MB.
    Mol Endocrinol; 2016 Feb 05; 30(2):201-16. PubMed ID: 26714229
    [Abstract] [Full Text] [Related]

  • 6. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY, Kim DH, Jun CB, Kim YM, Haar EV, Lee SI, Hegg JW, Bandhakavi S, Griffin TJ, Kim DH.
    J Biol Chem; 2007 Aug 31; 282(35):25604-12. PubMed ID: 17599906
    [Abstract] [Full Text] [Related]

  • 7. Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan.
    Lamming DW, Mihaylova MM, Katajisto P, Baar EL, Yilmaz OH, Hutchins A, Gultekin Y, Gaither R, Sabatini DM.
    Aging Cell; 2014 Oct 31; 13(5):911-7. PubMed ID: 25059582
    [Abstract] [Full Text] [Related]

  • 8. mTORC2 is required for proliferation and survival of TSC2-null cells.
    Goncharova EA, Goncharov DA, Li H, Pimtong W, Lu S, Khavin I, Krymskaya VP.
    Mol Cell Biol; 2011 Jun 31; 31(12):2484-98. PubMed ID: 21482669
    [Abstract] [Full Text] [Related]

  • 9. mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells.
    Smrz D, Kim MS, Zhang S, Mock BA, Smrzová S, DuBois W, Simakova O, Maric I, Wilson TM, Metcalfe DD, Gilfillan AM.
    Blood; 2011 Dec 22; 118(26):6803-13. PubMed ID: 22053105
    [Abstract] [Full Text] [Related]

  • 10. Genetic and pharmacologic evidence that mTOR targeting outweighs mTORC1 inhibition as an antimyeloma strategy.
    Chen X, Díaz-Rodríguez E, Ocio EM, Paiva B, Mortensen DS, Lopez-Girona A, Chopra R, Miguel JS, Pandiella A.
    Mol Cancer Ther; 2014 Feb 22; 13(2):504-16. PubMed ID: 24431075
    [Abstract] [Full Text] [Related]

  • 11. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA, Carriere A, Moreau J, Roux PP.
    Mol Cell Biol; 2010 Feb 22; 30(4):908-21. PubMed ID: 19995915
    [Abstract] [Full Text] [Related]

  • 12. Involvement of Rictor/mTORC2 in cardiomyocyte differentiation of mouse embryonic stem cells in vitro.
    Zheng B, Wang J, Tang L, Tan C, Zhao Z, Xiao Y, Ge R, Zhu D.
    Int J Biol Sci; 2017 Feb 22; 13(1):110-121. PubMed ID: 28123351
    [Abstract] [Full Text] [Related]

  • 13. Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells.
    Rosario FJ, Kanai Y, Powell TL, Jansson T.
    J Physiol; 2013 Feb 01; 591(3):609-25. PubMed ID: 23165769
    [Abstract] [Full Text] [Related]

  • 14. Mammalian target of rapamycin complex 2 (mTORC2) coordinates pulmonary artery smooth muscle cell metabolism, proliferation, and survival in pulmonary arterial hypertension.
    Goncharov DA, Kudryashova TV, Ziai H, Ihida-Stansbury K, DeLisser H, Krymskaya VP, Tuder RM, Kawut SM, Goncharova EA.
    Circulation; 2014 Feb 25; 129(8):864-74. PubMed ID: 24270265
    [Abstract] [Full Text] [Related]

  • 15. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes.
    Jhanwar-Uniyal M, Gillick JL, Neil J, Tobias M, Thwing ZE, Murali R.
    Adv Biol Regul; 2015 Jan 25; 57():64-74. PubMed ID: 25442674
    [Abstract] [Full Text] [Related]

  • 16. A comparison of Ku0063794, a dual mTORC1 and mTORC2 inhibitor, and temsirolimus in preclinical renal cell carcinoma models.
    Zhang H, Berel D, Wang Y, Li P, Bhowmick NA, Figlin RA, Kim HL.
    PLoS One; 2013 Jan 25; 8(1):e54918. PubMed ID: 23349989
    [Abstract] [Full Text] [Related]

  • 17. mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.
    Morrison MM, Young CD, Wang S, Sobolik T, Sanchez VM, Hicks DJ, Cook RS, Brantley-Sieders DM.
    PLoS Genet; 2015 Jul 25; 11(7):e1005291. PubMed ID: 26132202
    [Abstract] [Full Text] [Related]

  • 18. Mechanistic Target of Rapamycin Complex 1 (mTORC1) and mTORC2 as Key Signaling Intermediates in Mesenchymal Cell Activation.
    Walker NM, Belloli EA, Stuckey L, Chan KM, Lin J, Lynch W, Chang A, Mazzoni SM, Fingar DC, Lama VN.
    J Biol Chem; 2016 Mar 18; 291(12):6262-71. PubMed ID: 26755732
    [Abstract] [Full Text] [Related]

  • 19. Predominance of mTORC1 over mTORC2 in the regulation of proliferation of ovarian cancer cells: therapeutic implications.
    Montero JC, Chen X, Ocaña A, Pandiella A.
    Mol Cancer Ther; 2012 Jun 18; 11(6):1342-52. PubMed ID: 22496482
    [Abstract] [Full Text] [Related]

  • 20. Phosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling, Resulting in Enhanced Glioblastoma Growth and Invasiveness.
    Artinian N, Cloninger C, Holmes B, Benavides-Serrato A, Bashir T, Gera J.
    J Biol Chem; 2015 Aug 07; 290(32):19387-401. PubMed ID: 25998128
    [Abstract] [Full Text] [Related]

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