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Journal Abstract Search

188 related items for PubMed ID: 24025715

  • 1. Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells.
    Elsabrouty R, Jo Y, Dinh TT, DeBose-Boyd RA.
    Mol Biol Cell; 2013 Nov; 24(21):3300-8. PubMed ID: 24025715
    [Abstract] [Full Text] [Related]

  • 2. Sequential actions of the AAA-ATPase valosin-containing protein (VCP)/p97 and the proteasome 19 S regulatory particle in sterol-accelerated, endoplasmic reticulum (ER)-associated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Morris LL, Hartman IZ, Jun DJ, Seemann J, DeBose-Boyd RA.
    J Biol Chem; 2014 Jul 04; 289(27):19053-66. PubMed ID: 24860107
    [Abstract] [Full Text] [Related]

  • 3. Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.
    Jo Y, Lee PC, Sguigna PV, DeBose-Boyd RA.
    Proc Natl Acad Sci U S A; 2011 Dec 20; 108(51):20503-8. PubMed ID: 22143767
    [Abstract] [Full Text] [Related]

  • 4. Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cells.
    Nguyen AD, Lee SH, DeBose-Boyd RA.
    J Biol Chem; 2009 Sep 25; 284(39):26778-88. PubMed ID: 19638338
    [Abstract] [Full Text] [Related]

  • 5. Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase.
    Song BL, DeBose-Boyd RA.
    J Biol Chem; 2004 Jul 02; 279(27):28798-806. PubMed ID: 15090540
    [Abstract] [Full Text] [Related]

  • 6. Dislocation of HMG-CoA reductase and Insig-1, two polytopic endoplasmic reticulum proteins, en route to proteasomal degradation.
    Leichner GS, Avner R, Harats D, Roitelman J.
    Mol Biol Cell; 2009 Jul 02; 20(14):3330-41. PubMed ID: 19458199
    [Abstract] [Full Text] [Related]

  • 7. Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.
    Jiang LY, Jiang W, Tian N, Xiong YN, Liu J, Wei J, Wu KY, Luo J, Shi XJ, Song BL.
    J Biol Chem; 2018 Mar 16; 293(11):4047-4055. PubMed ID: 29374057
    [Abstract] [Full Text] [Related]

  • 8. Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol.
    Sever N, Song BL, Yabe D, Goldstein JL, Brown MS, DeBose-Boyd RA.
    J Biol Chem; 2003 Dec 26; 278(52):52479-90. PubMed ID: 14563840
    [Abstract] [Full Text] [Related]

  • 9. Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet-associated endoplasmic reticulum membranes.
    Jo Y, Hartman IZ, DeBose-Boyd RA.
    Mol Biol Cell; 2013 Feb 26; 24(3):169-83. PubMed ID: 23223569
    [Abstract] [Full Text] [Related]

  • 10. Isolation of sterol-resistant Chinese hamster ovary cells with genetic deficiencies in both Insig-1 and Insig-2.
    Lee PC, Sever N, Debose-Boyd RA.
    J Biol Chem; 2005 Jul 01; 280(26):25242-9. PubMed ID: 15866869
    [Abstract] [Full Text] [Related]

  • 11. Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase.
    Song BL, Sever N, DeBose-Boyd RA.
    Mol Cell; 2005 Sep 16; 19(6):829-40. PubMed ID: 16168377
    [Abstract] [Full Text] [Related]

  • 12. Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets.
    Hartman IZ, Liu P, Zehmer JK, Luby-Phelps K, Jo Y, Anderson RG, DeBose-Boyd RA.
    J Biol Chem; 2010 Jun 18; 285(25):19288-98. PubMed ID: 20406816
    [Abstract] [Full Text] [Related]

  • 13. Underlying mechanisms for sterol-induced ubiquitination and ER-associated degradation of HMG CoA reductase.
    Johnson BM, DeBose-Boyd RA.
    Semin Cell Dev Biol; 2018 Sep 18; 81():121-128. PubMed ID: 29107682
    [Abstract] [Full Text] [Related]

  • 14. Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase.
    Jo Y, Debose-Boyd RA.
    Crit Rev Biochem Mol Biol; 2010 Jun 18; 45(3):185-98. PubMed ID: 20482385
    [Abstract] [Full Text] [Related]

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  • 17. Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Sever N, Lee PC, Song BL, Rawson RB, Debose-Boyd RA.
    J Biol Chem; 2004 Oct 08; 279(41):43136-47. PubMed ID: 15247248
    [Abstract] [Full Text] [Related]

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  • 19. Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78.
    Lee JN, Song B, DeBose-Boyd RA, Ye J.
    J Biol Chem; 2006 Dec 22; 281(51):39308-15. PubMed ID: 17043353
    [Abstract] [Full Text] [Related]

  • 20. Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells.
    Lee PC, DeBose-Boyd RA.
    J Lipid Res; 2010 Jan 22; 51(1):192-201. PubMed ID: 19617589
    [Abstract] [Full Text] [Related]

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