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284 related items for PubMed ID: 24039860

  • 1. Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo.
    Wittchen ES, Nishimura E, McCloskey M, Wang H, Quilliam LA, Chrzanowska-Wodnicka M, Hartnett ME.
    PLoS One; 2013; 8(9):e73070. PubMed ID: 24039860
    [Abstract] [Full Text] [Related]

  • 2. Activation of the Small GTPase Rap1 Inhibits Choroidal Neovascularization by Regulating Cell Junctions and ROS Generation in Rats.
    Li J, Zhang R, Wang C, Wang X, Xu M, Ma J, Shang Q.
    Curr Eye Res; 2018 Jul; 43(7):934-940. PubMed ID: 29601231
    [Abstract] [Full Text] [Related]

  • 3. Activation of Rap1 inhibits NADPH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization.
    Wang H, Jiang Y, Shi D, Quilliam LA, Chrzanowska-Wodnicka M, Wittchen ES, Li DY, Hartnett ME.
    FASEB J; 2014 Jan; 28(1):265-74. PubMed ID: 24043260
    [Abstract] [Full Text] [Related]

  • 4. Active Rap1-mediated inhibition of choroidal neovascularization requires interactions with IQGAP1 in choroidal endothelial cells.
    Ramshekar A, Wang H, Kunz E, Pappas C, Hageman GS, Chaqour B, Sacks DB, Hartnett ME.
    FASEB J; 2021 Jul; 35(7):e21642. PubMed ID: 34166557
    [Abstract] [Full Text] [Related]

  • 5. The small GTPase Rap1 is a novel regulator of RPE cell barrier function.
    Wittchen ES, Hartnett ME.
    Invest Ophthalmol Vis Sci; 2011 Sep 27; 52(10):7455-63. PubMed ID: 21873678
    [Abstract] [Full Text] [Related]

  • 6. Optimal Inhibition of Choroidal Neovascularization by scAAV2 with VMD2 Promoter-driven Active Rap1a in the RPE.
    Wang H, Kunz E, Stoddard GJ, Hauswirth WW, Hartnett ME.
    Sci Rep; 2019 Oct 31; 9(1):15732. PubMed ID: 31673119
    [Abstract] [Full Text] [Related]

  • 7. Rap1 GTPase Inhibits Tumor Necrosis Factor-α-Induced Choroidal Endothelial Migration via NADPH Oxidase- and NF-κB-Dependent Activation of Rac1.
    Wang H, Fotheringham L, Wittchen ES, Hartnett ME.
    Am J Pathol; 2015 Dec 31; 185(12):3316-25. PubMed ID: 26476350
    [Abstract] [Full Text] [Related]

  • 8. Prostacyclin post-treatment improves LPS-induced acute lung injury and endothelial barrier recovery via Rap1.
    Birukova AA, Meng F, Tian Y, Meliton A, Sarich N, Quilliam LA, Birukov KG.
    Biochim Biophys Acta; 2015 May 31; 1852(5):778-91. PubMed ID: 25545047
    [Abstract] [Full Text] [Related]

  • 9. Thy-1 Regulates VEGF-Mediated Choroidal Endothelial Cell Activation and Migration: Implications in Neovascular Age-Related Macular Degeneration.
    Wang H, Han X, Kunz E, Hartnett ME.
    Invest Ophthalmol Vis Sci; 2016 Oct 01; 57(13):5525-5534. PubMed ID: 27768790
    [Abstract] [Full Text] [Related]

  • 10. Breaking barriers: insight into the pathogenesis of neovascular age-related macular degeneration.
    Wang H, Wittchen ES, Hartnett ME.
    Eye Brain; 2011 Oct 01; 3():19-28. PubMed ID: 27795668
    [Abstract] [Full Text] [Related]

  • 11. Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions.
    Yan J, Li F, Ingram DA, Quilliam LA.
    Mol Cell Biol; 2008 Sep 01; 28(18):5803-10. PubMed ID: 18625726
    [Abstract] [Full Text] [Related]

  • 12. Rap1 small GTPase is essential for maintaining pulmonary endothelial barrier function in mice.
    Yamamoto K, Watanabe-Takano H, Oguri-Nakamura E, Matsuno H, Horikami D, Ishii T, Ohashi R, Kubota Y, Nishiyama K, Murata T, Mochizuki N, Fukuhara S.
    FASEB J; 2023 Dec 01; 37(12):e23310. PubMed ID: 38010922
    [Abstract] [Full Text] [Related]

  • 13. Distinct effects of complement and of NLRP3- and non-NLRP3 inflammasomes for choroidal neovascularization.
    Malsy J, Alvarado AC, Lamontagne JO, Strittmatter K, Marneros AG.
    Elife; 2020 Dec 11; 9():. PubMed ID: 33305736
    [Abstract] [Full Text] [Related]

  • 14. Implication of N-Methyl-d-Aspartate Receptor in Homocysteine-Induced Age-Related Macular Degeneration.
    Samra YA, Kira D, Rajpurohit P, Mohamed R, Owen LA, Shakoor A, Kim IK, DeAngelis MM, Sheibani N, Al-Shabrawey M, Tawfik A.
    Int J Mol Sci; 2021 Aug 28; 22(17):. PubMed ID: 34502266
    [Abstract] [Full Text] [Related]

  • 15. Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis.
    Carmona G, Göttig S, Orlandi A, Scheele J, Bäuerle T, Jugold M, Kiessling F, Henschler R, Zeiher AM, Dimmeler S, Chavakis E.
    Blood; 2009 Jan 08; 113(2):488-97. PubMed ID: 18805968
    [Abstract] [Full Text] [Related]

  • 16. Small GTPase Rap1A/B Is Required for Lymphatic Development and Adrenomedullin-Induced Stabilization of Lymphatic Endothelial Junctions.
    Xu W, Wittchen ES, Hoopes SL, Stefanini L, Burridge K, Caron KM.
    Arterioscler Thromb Vasc Biol; 2018 Oct 08; 38(10):2410-2422. PubMed ID: 30354217
    [Abstract] [Full Text] [Related]

  • 17. Targeting of junctional adhesion molecule-C inhibits experimental choroidal neovascularization.
    Hou X, Hu D, Wang YS, Tang ZS, Zhang F, Chavakis T, Li Y, Li X.
    Invest Ophthalmol Vis Sci; 2012 Mar 08; 53(3):1584-91. PubMed ID: 22323465
    [Abstract] [Full Text] [Related]

  • 18. Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization.
    Wang H, Han X, Bretz CA, Becker S, Gambhir D, Smith GW, Samulski RJ, Wittchen ES, Quilliam LA, Chrzanowska-Wodnicka M, Hartnett ME.
    Mol Ther Methods Clin Dev; 2016 Mar 08; 3():16056. PubMed ID: 27606349
    [Abstract] [Full Text] [Related]

  • 19. The role of sphingosine 1-phosphate receptors on retinal pigment epithelial cells barrier function and angiogenic effects.
    Terao R, Honjo M, Totsuka K, Miwa Y, Kurihara T, Aihara M.
    Prostaglandins Other Lipid Mediat; 2019 Dec 08; 145():106365. PubMed ID: 31415870
    [Abstract] [Full Text] [Related]

  • 20. The role of RPE cell-associated VEGF₁₈₉ in choroidal endothelial cell transmigration across the RPE.
    Wang H, Geisen P, Wittchen ES, King B, Burridge K, D'Amore PA, Hartnett ME.
    Invest Ophthalmol Vis Sci; 2011 Jan 08; 52(1):570-8. PubMed ID: 20811045
    [Abstract] [Full Text] [Related]

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