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322 related items for PubMed ID: 24085292

  • 1. Long-term incubation with proteasome inhibitors (PIs) induces IκBα degradation via the lysosomal pathway in an IκB kinase (IKK)-dependent and IKK-independent manner.
    Lee KH, Jeong J, Yoo CG.
    J Biol Chem; 2013 Nov 08; 288(45):32777-32786. PubMed ID: 24085292
    [Abstract] [Full Text] [Related]

  • 2. Proteasome Inhibitor-Induced IκB/NF-κB Activation is Mediated by Nrf2-Dependent Light Chain 3B Induction in Lung Cancer Cells.
    Lee KH, Lee J, Woo J, Lee CH, Yoo CG.
    Mol Cells; 2018 Dec 31; 41(12):1008-1015. PubMed ID: 30396235
    [Abstract] [Full Text] [Related]

  • 3. Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells.
    Hideshima T, Ikeda H, Chauhan D, Okawa Y, Raje N, Podar K, Mitsiades C, Munshi NC, Richardson PG, Carrasco RD, Anderson KC.
    Blood; 2009 Jul 30; 114(5):1046-52. PubMed ID: 19436050
    [Abstract] [Full Text] [Related]

  • 4. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S, Gutierrez AM, Lotan R, Aggarwal BB.
    Cancer Res; 2005 Oct 15; 65(20):9555-65. PubMed ID: 16230421
    [Abstract] [Full Text] [Related]

  • 5. The heat-shock-induced suppression of the IkappaB/NF-kappaB cascade is due to inactivation of upstream regulators of IkappaBalpha through insolubilization.
    Lee KH, Hwang YH, Lee CT, Kim YW, Han SK, Shim YS, Yoo CG.
    Exp Cell Res; 2004 Sep 10; 299(1):49-56. PubMed ID: 15302572
    [Abstract] [Full Text] [Related]

  • 6. Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor.
    Takada Y, Fang X, Jamaluddin MS, Boyd DD, Aggarwal BB.
    J Biol Chem; 2004 Sep 17; 279(38):39541-54. PubMed ID: 15252041
    [Abstract] [Full Text] [Related]

  • 7. 17-Allylamino-17-Demethoxygeldanamycin and the Enhancement of PS-341-Induced Lung Cancer Cell Death by Blocking the NF-κB and PI3K/Akt Pathways.
    Lee KH, Jang AH, Yoo CG.
    Am J Respir Cell Mol Biol; 2015 Sep 17; 53(3):412-21. PubMed ID: 25633180
    [Abstract] [Full Text] [Related]

  • 8. Glycogen synthase kinase 3beta-mediated apoptosis of primary cortical astrocytes involves inhibition of nuclear factor kappaB signaling.
    Sanchez JF, Sniderhan LF, Williamson AL, Fan S, Chakraborty-Sett S, Maggirwar SB.
    Mol Cell Biol; 2003 Jul 17; 23(13):4649-62. PubMed ID: 12808104
    [Abstract] [Full Text] [Related]

  • 9. Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells.
    Zhang JS, Herreros-Villanueva M, Koenig A, Deng Z, de Narvajas AA, Gomez TS, Meng X, Bujanda L, Ellenrieder V, Li XK, Kaufmann SH, Billadeau DD.
    Cell Death Dis; 2014 Mar 27; 5(3):e1142. PubMed ID: 24675460
    [Abstract] [Full Text] [Related]

  • 10. Nuclear IKKbeta is an adaptor protein for IkappaBalpha ubiquitination and degradation in UV-induced NF-kappaB activation.
    Tsuchiya Y, Asano T, Nakayama K, Kato T, Karin M, Kamata H.
    Mol Cell; 2010 Aug 27; 39(4):570-82. PubMed ID: 20797629
    [Abstract] [Full Text] [Related]

  • 11. Heat shock protein 70 negatively regulates the heat-shock-induced suppression of the IkappaB/NF-kappaB cascade by facilitating IkappaB kinase renaturation and blocking its further denaturation.
    Lee KH, Lee CT, Kim YW, Han SK, Shim YS, Yoo CG.
    Exp Cell Res; 2005 Jul 01; 307(1):276-84. PubMed ID: 15922746
    [Abstract] [Full Text] [Related]

  • 12. Bortezomib inhibits proteasomal degradation of IκBα and induces mitochondrial dependent apoptosis in activated B-cell diffuse large B-cell lymphoma.
    Bu R, Hussain AR, Al-Obaisi KA, Ahmed M, Uddin S, Al-Kuraya KS.
    Leuk Lymphoma; 2014 Feb 01; 55(2):415-24. PubMed ID: 23697845
    [Abstract] [Full Text] [Related]

  • 13. Arsenic inhibits NF-kappaB-mediated gene transcription by blocking IkappaB kinase activity and IkappaBalpha phosphorylation and degradation.
    Roussel RR, Barchowsky A.
    Arch Biochem Biophys; 2000 May 01; 377(1):204-12. PubMed ID: 10775461
    [Abstract] [Full Text] [Related]

  • 14. Ionizing radiation can induce GSK-3beta phosphorylation and NF-kappaB transcriptional transactivation in ATM-deficient fibroblasts.
    Kwon O, Kim KA, He L, Kim SO, Kim MS, Cha EY, Yoon BD, Sok DE, Jung M, Ahn JS, Kim BY.
    Cell Signal; 2008 Apr 01; 20(4):602-12. PubMed ID: 18243662
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of IKK down-regulates antigen + IgE-induced TNF production by mast cells: a role for the IKK-IkappaB-NF-kappaB pathway in IgE-dependent mast cell activation.
    Peng Y, Power MR, Li B, Lin TJ.
    J Leukoc Biol; 2005 Jun 01; 77(6):975-83. PubMed ID: 15784689
    [Abstract] [Full Text] [Related]

  • 16. Bortezomib induces nuclear translocation of IκBα resulting in gene-specific suppression of NF-κB--dependent transcription and induction of apoptosis in CTCL.
    Juvekar A, Manna S, Ramaswami S, Chang TP, Vu HY, Ghosh CC, Celiker MY, Vancurova I.
    Mol Cancer Res; 2011 Feb 01; 9(2):183-94. PubMed ID: 21224428
    [Abstract] [Full Text] [Related]

  • 17. IKKβ inhibitor in combination with bortezomib induces cytotoxicity in breast cancer cells.
    Hideshima H, Yoshida Y, Ikeda H, Hide M, Iwasaki A, Anderson KC, Hideshima T.
    Int J Oncol; 2014 Apr 01; 44(4):1171-6. PubMed ID: 24481412
    [Abstract] [Full Text] [Related]

  • 18. NF-kappa B as a therapeutic target in multiple myeloma.
    Hideshima T, Chauhan D, Richardson P, Mitsiades C, Mitsiades N, Hayashi T, Munshi N, Dang L, Castro A, Palombella V, Adams J, Anderson KC.
    J Biol Chem; 2002 May 10; 277(19):16639-47. PubMed ID: 11872748
    [Abstract] [Full Text] [Related]

  • 19. Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells.
    Xu C, Shen G, Chen C, Gélinas C, Kong AN.
    Oncogene; 2005 Jun 30; 24(28):4486-95. PubMed ID: 15856023
    [Abstract] [Full Text] [Related]

  • 20. Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death.
    Piazza F, Manni S, Tubi LQ, Montini B, Pavan L, Colpo A, Gnoato M, Cabrelle A, Adami F, Zambello R, Trentin L, Gurrieri C, Semenzato G.
    BMC Cancer; 2010 Oct 04; 10():526. PubMed ID: 20920357
    [Abstract] [Full Text] [Related]


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