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Journal Abstract Search

169 related items for PubMed ID: 24097670

  • 1. Hepatic clearance of 6 polycyclic aromatic hydrocarbons by isolated perfused trout livers: prediction from in vitro clearance by liver S9 fractions.
    Nichols JW, Hoffman AD, ter Laak TL, Fitzsimmons PN.
    Toxicol Sci; 2013 Dec; 136(2):359-72. PubMed ID: 24097670
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  • 2. Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish.
    Fay KA, Fitzsimmons PN, Hoffman AD, Nichols JW.
    Environ Toxicol Chem; 2017 Feb; 36(2):463-471. PubMed ID: 27487575
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  • 3. Protein and lipid binding parameters in rainbow trout (Oncorhynchus mykiss) blood and liver fractions to extrapolate from an in vitro metabolic degradation assay to in vivo bioaccumulation potential of hydrophobic organic chemicals.
    Escher BI, Cowan-Ellsberry CE, Dyer S, Embry MR, Erhardt S, Halder M, Kwon JH, Johanning K, Oosterwijk MT, Rutishauser S, Segner H, Nichols J.
    Chem Res Toxicol; 2011 Jul 18; 24(7):1134-43. PubMed ID: 21604782
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  • 6. Optimization of an isolated perfused rainbow trout liver model: Clearance studies with 7-ethoxycoumarin.
    Nichols JW, Hoffman AD, Fitzsimmons PN.
    Aquat Toxicol; 2009 Nov 27; 95(3):182-94. PubMed ID: 19837470
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  • 13. Liver microsomes and S9 from rainbow trout (Oncorhynchus mykiss): comparison of basal-level enzyme activities with rat and determination of xenobiotic intrinsic clearance in support of bioaccumulation assessment.
    Han X, Nabb DL, Yang CH, Snajdr SI, Mingoia RT.
    Environ Toxicol Chem; 2009 Mar 27; 28(3):481-8. PubMed ID: 18937539
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  • 14. Determination of xenobiotic intrinsic clearance in freshly isolated hepatocytes from rainbow trout (Oncorhynchus mykiss) and rat and its application in bioaccumulation assessment.
    Han X, Nabb DL, Mingoia RT, Yang CH.
    Environ Sci Technol; 2007 May 01; 41(9):3269-76. PubMed ID: 17539536
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  • 16. Xenobiotic intrinsic clearance in freshly isolated hepatocytes from rainbow trout (Oncorhynchus mykiss): determination of trout hepatocellularity, optimization of cell concentrations and comparison of serum and serum-free incubations.
    Han X, Mingoia RT, Nabb DL, Yang CH, Snajdr SI, Hoke RA.
    Aquat Toxicol; 2008 Aug 11; 89(1):11-7. PubMed ID: 18599132
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  • 17. Validation of Methods for in Vitro-in Vivo Extrapolation Using Hepatic Clearance Measurements in Isolated Perfused Fish Livers.
    Schultz M, Krause S, Brinkmann M.
    Environ Sci Technol; 2022 Sep 06; 56(17):12416-12423. PubMed ID: 35994365
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  • 18. In Vitro Biotransformation Assays Using Liver S9 Fractions and Hepatocytes from Rainbow Trout (Oncorhynchus mykiss): Overcoming Challenges with Difficult to Test Fragrance Chemicals.
    Kropf C, Begnaud F, Gimeno S, Berthaud F, Debonneville C, Segner H.
    Environ Toxicol Chem; 2020 Dec 06; 39(12):2396-2408. PubMed ID: 32915480
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  • 19. Measurement of kinetic parameters for biotransformation of polycyclic aromatic hydrocarbons by trout liver S9 fractions: Implications for bioaccumulation assessment.
    Nichols JW, Ladd MA, Fitzsimmons PN.
    Appl In Vitro Toxicol; 2018 Dec 06; 4(4):365-378. PubMed ID: 31179352
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  • 20. Tissue-specific metabolism of benzo[a]pyrene in rainbow trout (Oncorhynchus mykiss): a comparison between the liver and immune organs.
    Möller AM, Hermsen C, Floehr T, Lamoree MH, Segner H.
    Drug Metab Dispos; 2014 Jan 06; 42(1):111-8. PubMed ID: 24144719
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