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219 related items for PubMed ID: 24099598

  • 1. Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells.
    Barlow J, Affourtit C.
    Biochem J; 2013 Dec 15; 456(3):417-26. PubMed ID: 24099598
    [Abstract] [Full Text] [Related]

  • 2. Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells.
    Barlow J, Hirschberg Jensen V, Affourtit C.
    Redox Biol; 2015 Dec 15; 4():14-22. PubMed ID: 25482405
    [Abstract] [Full Text] [Related]

  • 3. Pro-inflammatory cytokines attenuate glucose-stimulated insulin secretion from INS-1E insulinoma cells by restricting mitochondrial pyruvate oxidation capacity - Novel mechanistic insight from real-time analysis of oxidative phosphorylation.
    Barlow J, Solomon TPJ, Affourtit C.
    PLoS One; 2018 Dec 15; 13(6):e0199505. PubMed ID: 29953508
    [Abstract] [Full Text] [Related]

  • 4. Mitochondrial uncoupling protein-2 is not involved in palmitate-induced impairment of glucose-stimulated insulin secretion in INS-1E insulinoma cells and is not needed for the amplification of insulin release.
    Hirschberg Jensen V, Affourtit C.
    Biochem Biophys Rep; 2015 May 15; 1():8-15. PubMed ID: 26339685
    [Abstract] [Full Text] [Related]

  • 5. Uncoupling protein-2 attenuates glucose-stimulated insulin secretion in INS-1E insulinoma cells by lowering mitochondrial reactive oxygen species.
    Affourtit C, Jastroch M, Brand MD.
    Free Radic Biol Med; 2011 Mar 01; 50(5):609-16. PubMed ID: 21172424
    [Abstract] [Full Text] [Related]

  • 6. Glucose-stimulated insulin secretion of insulinoma INS-1E cells is associated with elevation of both respiration and mitochondrial membrane potential.
    Spacek T, Santorová J, Zacharovová K, Berková Z, Hlavatá L, Saudek F, Jezek P.
    Int J Biochem Cell Biol; 2008 Mar 01; 40(8):1522-35. PubMed ID: 18248766
    [Abstract] [Full Text] [Related]

  • 7. Palmitate-induced impairment of glucose-stimulated insulin secretion precedes mitochondrial dysfunction in mouse pancreatic islets.
    Barlow J, Jensen VH, Jastroch M, Affourtit C.
    Biochem J; 2016 Feb 15; 473(4):487-96. PubMed ID: 26621874
    [Abstract] [Full Text] [Related]

  • 8. Uncoupling protein-2 contributes significantly to high mitochondrial proton leak in INS-1E insulinoma cells and attenuates glucose-stimulated insulin secretion.
    Affourtit C, Brand MD.
    Biochem J; 2008 Jan 01; 409(1):199-204. PubMed ID: 17824844
    [Abstract] [Full Text] [Related]

  • 9. Antibiotics induce mitonuclear protein imbalance but fail to inhibit respiration and nutrient activation in pancreatic β-cells.
    Santo-Domingo J, Chareyron I, Broenimann C, Lassueur S, Wiederkehr A.
    Exp Cell Res; 2017 Aug 15; 357(2):170-180. PubMed ID: 28527697
    [Abstract] [Full Text] [Related]

  • 10. Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic β Cells Due to Decreasing Mitochondrial Matrix NADH/NAD+ Ratio.
    Plecitá-Hlavatá L, Engstová H, Holendová B, Tauber J, Špaček T, Petrásková L, Křen V, Špačková J, Gotvaldová K, Ježek J, Dlasková A, Smolková K, Ježek P.
    Antioxid Redox Signal; 2020 Oct 20; 33(12):789-815. PubMed ID: 32517485
    [Abstract] [Full Text] [Related]

  • 11. Essential role of mitochondrial Ca2+ uniporter in the generation of mitochondrial pH gradient and metabolism-secretion coupling in insulin-releasing cells.
    Quan X, Nguyen TT, Choi SK, Xu S, Das R, Cha SK, Kim N, Han J, Wiederkehr A, Wollheim CB, Park KS.
    J Biol Chem; 2015 Feb 13; 290(7):4086-96. PubMed ID: 25548283
    [Abstract] [Full Text] [Related]

  • 12. Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism.
    Vetterli L, Brun T, Giovannoni L, Bosco D, Maechler P.
    J Biol Chem; 2011 Feb 25; 286(8):6049-60. PubMed ID: 21163946
    [Abstract] [Full Text] [Related]

  • 13. PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction.
    Ravnskjaer K, Frigerio F, Boergesen M, Nielsen T, Maechler P, Mandrup S.
    J Lipid Res; 2010 Jun 25; 51(6):1370-9. PubMed ID: 19965574
    [Abstract] [Full Text] [Related]

  • 14. Role for malic enzyme, pyruvate carboxylation, and mitochondrial malate import in glucose-stimulated insulin secretion.
    Heart E, Cline GW, Collis LP, Pongratz RL, Gray JP, Smith PJ.
    Am J Physiol Endocrinol Metab; 2009 Jun 25; 296(6):E1354-62. PubMed ID: 19293334
    [Abstract] [Full Text] [Related]

  • 15. Glucose stimulation induces dynamic change of mitochondrial morphology to promote insulin secretion in the insulinoma cell line INS-1E.
    Jhun BS, Lee H, Jin ZG, Yoon Y.
    PLoS One; 2013 Jun 25; 8(4):e60810. PubMed ID: 23565276
    [Abstract] [Full Text] [Related]

  • 16. Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.
    Joseph JW, Koshkin V, Saleh MC, Sivitz WI, Zhang CY, Lowell BB, Chan CB, Wheeler MB.
    J Biol Chem; 2004 Dec 03; 279(49):51049-56. PubMed ID: 15448158
    [Abstract] [Full Text] [Related]

  • 17. Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells.
    Park KS, Wiederkehr A, Kirkpatrick C, Mattenberger Y, Martinou JC, Marchetti P, Demaurex N, Wollheim CB.
    J Biol Chem; 2008 Nov 28; 283(48):33347-56. PubMed ID: 18832378
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