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Journal Abstract Search

254 related items for PubMed ID: 24100507

  • 1. MLS-2384, a new 6-bromoindirubin derivative with dual JAK/Src kinase inhibitory activity, suppresses growth of diverse cancer cells.
    Liu L, Gaboriaud N, Vougogianopoulou K, Tian Y, Wu J, Wen W, Skaltsounis L, Jove R.
    Cancer Biol Ther; 2014 Feb; 15(2):178-84. PubMed ID: 24100507
    [Abstract] [Full Text] [Related]

  • 2. A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling.
    Liu L, Kritsanida M, Magiatis P, Gaboriaud N, Wang Y, Wu J, Buettner R, Yang F, Nam S, Skaltsounis L, Jove R.
    Cancer Biol Ther; 2012 Nov; 13(13):1255-61. PubMed ID: 22895078
    [Abstract] [Full Text] [Related]

  • 3. 6-Bromoindirubin-3'-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells.
    Liu L, Nam S, Tian Y, Yang F, Wu J, Wang Y, Scuto A, Polychronopoulos P, Magiatis P, Skaltsounis L, Jove R.
    Cancer Res; 2011 Jun 01; 71(11):3972-9. PubMed ID: 21610112
    [Abstract] [Full Text] [Related]

  • 4. Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells.
    Nam S, Wen W, Schroeder A, Herrmann A, Yu H, Cheng X, Merz KH, Eisenbrand G, Li H, Yuan YC, Jove R.
    Mol Oncol; 2013 Jun 01; 7(3):369-78. PubMed ID: 23206899
    [Abstract] [Full Text] [Related]

  • 5. Sustained Src inhibition results in signal transducer and activator of transcription 3 (STAT3) activation and cancer cell survival via altered Janus-activated kinase-STAT3 binding.
    Sen B, Saigal B, Parikh N, Gallick G, Johnson FM.
    Cancer Res; 2009 Mar 01; 69(5):1958-65. PubMed ID: 19223541
    [Abstract] [Full Text] [Related]

  • 6. Spirooxindole derivative SOID-8 induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.
    Tian Y, Nam S, Liu L, Yakushijin F, Yakushijin K, Buettner R, Liang W, Yang F, Ma Y, Horne D, Jove R.
    PLoS One; 2012 Mar 01; 7(11):e49306. PubMed ID: 23166634
    [Abstract] [Full Text] [Related]

  • 7. Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells.
    Park KW, Kundu J, Chae IG, Kim DH, Yu MH, Kundu JK, Chun KS.
    Int J Oncol; 2014 Apr 01; 44(4):1309-15. PubMed ID: 24481553
    [Abstract] [Full Text] [Related]

  • 8. Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2- and Src‑mediated phosphorylation of EGF receptor tyrosine kinase.
    Kundu J, Choi BY, Jeong CH, Kundu JK, Chun KS.
    Oncol Rep; 2014 Aug 01; 32(2):821-8. PubMed ID: 24890449
    [Abstract] [Full Text] [Related]

  • 9. Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro.
    Zhu WQ, Wang J, Guo XF, Liu Z, Dong WG.
    World J Gastroenterol; 2016 Apr 28; 22(16):4149-59. PubMed ID: 27122665
    [Abstract] [Full Text] [Related]

  • 10. Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells.
    Garcia R, Bowman TL, Niu G, Yu H, Minton S, Muro-Cacho CA, Cox CE, Falcone R, Fairclough R, Parsons S, Laudano A, Gazit A, Levitzki A, Kraker A, Jove R.
    Oncogene; 2001 May 03; 20(20):2499-513. PubMed ID: 11420660
    [Abstract] [Full Text] [Related]

  • 11. Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells.
    Proietti C, Salatino M, Rosemblit C, Carnevale R, Pecci A, Kornblihtt AR, Molinolo AA, Frahm I, Charreau EH, Schillaci R, Elizalde PV.
    Mol Cell Biol; 2005 Jun 03; 25(12):4826-40. PubMed ID: 15923602
    [Abstract] [Full Text] [Related]

  • 12. Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice.
    Blaskovich MA, Sun J, Cantor A, Turkson J, Jove R, Sebti SM.
    Cancer Res; 2003 Mar 15; 63(6):1270-9. PubMed ID: 12649187
    [Abstract] [Full Text] [Related]

  • 13. Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases.
    Kreis S, Munz GA, Haan S, Heinrich PC, Behrmann I.
    Mol Cancer Res; 2007 Dec 15; 5(12):1331-41. PubMed ID: 18171991
    [Abstract] [Full Text] [Related]

  • 14. SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.
    Duan Z, Bradner JE, Greenberg E, Levine R, Foster R, Mahoney J, Seiden MV.
    Clin Cancer Res; 2006 Nov 15; 12(22):6844-52. PubMed ID: 17121906
    [Abstract] [Full Text] [Related]

  • 15. Anti-angiogenic activity of thienopyridine derivative LCB03-0110 by targeting VEGFR-2 and JAK/STAT3 Signalling.
    Kim BH, Lee Y, Yoo H, Cui M, Lee S, Kim SY, Cho JU, Lee H, Yang BS, Kwon YG, Choi S, Kim TY.
    Exp Dermatol; 2015 Jul 15; 24(7):503-9. PubMed ID: 25808463
    [Abstract] [Full Text] [Related]

  • 16. JAK2 regulation by licochalcone H inhibits the cell growth and induces apoptosis in oral squamous cell carcinoma.
    Oh HN, Oh KB, Lee MH, Seo JH, Kim E, Yoon G, Cho SS, Cho YS, Choi HW, Chae JI, Shim JH.
    Phytomedicine; 2019 Jan 15; 52():60-69. PubMed ID: 30599913
    [Abstract] [Full Text] [Related]

  • 17. Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3.
    Yang F, Brown C, Buettner R, Hedvat M, Starr R, Scuto A, Schroeder A, Jensen M, Jove R.
    Mol Cancer Ther; 2010 Apr 15; 9(4):953-62. PubMed ID: 20371721
    [Abstract] [Full Text] [Related]

  • 18. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.
    Lin L, Hutzen B, Li PK, Ball S, Zuo M, DeAngelis S, Foust E, Sobo M, Friedman L, Bhasin D, Cen L, Li C, Lin J.
    Neoplasia; 2010 Jan 15; 12(1):39-50. PubMed ID: 20072652
    [Abstract] [Full Text] [Related]

  • 19. Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.
    Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G.
    J Pharmacol Exp Ther; 2010 Jul 15; 334(1):285-93. PubMed ID: 20378717
    [Abstract] [Full Text] [Related]

  • 20. Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein.
    Kotha A, Sekharam M, Cilenti L, Siddiquee K, Khaled A, Zervos AS, Carter B, Turkson J, Jove R.
    Mol Cancer Ther; 2006 Mar 15; 5(3):621-9. PubMed ID: 16546976
    [Abstract] [Full Text] [Related]

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