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139 related items for PubMed ID: 24120758

  • 1. Targeting Mcl-1 for multiple myeloma (MM) therapy: drug-induced generation of Mcl-1 fragment Mcl-1(128-350) triggers MM cell death via c-Jun upregulation.
    Fan F, Tonon G, Bashari MH, Vallet S, Antonini E, Goldschmidt H, Schulze-Bergkamen H, Opferman JT, Sattler M, Anderson KC, Jäger D, Podar K.
    Cancer Lett; 2014 Feb 28; 343(2):286-94. PubMed ID: 24120758
    [Abstract] [Full Text] [Related]

  • 2. A pivotal role for Mcl-1 in Bortezomib-induced apoptosis.
    Podar K, Gouill SL, Zhang J, Opferman JT, Zorn E, Tai YT, Hideshima T, Amiot M, Chauhan D, Harousseau JL, Anderson KC.
    Oncogene; 2008 Jan 31; 27(6):721-31. PubMed ID: 17653083
    [Abstract] [Full Text] [Related]

  • 3. Noxa up-regulation and Mcl-1 cleavage are associated to apoptosis induction by bortezomib in multiple myeloma.
    Gomez-Bougie P, Wuillème-Toumi S, Ménoret E, Trichet V, Robillard N, Philippe M, Bataille R, Amiot M.
    Cancer Res; 2007 Jun 01; 67(11):5418-24. PubMed ID: 17545623
    [Abstract] [Full Text] [Related]

  • 4. Mcl-1 downregulation sensitizes glioma to bortezomib-induced apoptosis.
    Zhang Y, Zhu X, Hou K, Zhao J, Han Z, Zhang X.
    Oncol Rep; 2015 May 01; 33(5):2277-84. PubMed ID: 25812695
    [Abstract] [Full Text] [Related]

  • 5. JNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways.
    Lauricella M, Emanuele S, D'Anneo A, Calvaruso G, Vassallo B, Carlisi D, Portanova P, Vento R, Tesoriere G.
    Apoptosis; 2006 Apr 01; 11(4):607-25. PubMed ID: 16528474
    [Abstract] [Full Text] [Related]

  • 6. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors.
    Pei XY, Dai Y, Grant S.
    Clin Cancer Res; 2004 Jun 01; 10(11):3839-52. PubMed ID: 15173093
    [Abstract] [Full Text] [Related]

  • 7. Up-regulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma.
    Podar K, Raab MS, Tonon G, Sattler M, Barilà D, Zhang J, Tai YT, Yasui H, Raje N, DePinho RA, Hideshima T, Chauhan D, Anderson KC.
    Cancer Res; 2007 Feb 15; 67(4):1680-8. PubMed ID: 17308109
    [Abstract] [Full Text] [Related]

  • 8. Triptolide induces apoptotic cell death of multiple myeloma cells via transcriptional repression of Mcl-1.
    Nakazato T, Sagawa M, Kizaki M.
    Int J Oncol; 2014 Apr 15; 44(4):1131-8. PubMed ID: 24481531
    [Abstract] [Full Text] [Related]

  • 9. Evidence against a direct role for the induction of c-jun expression in the mediation of drug-induced apoptosis in human acute leukemia cells.
    Bullock G, Ray S, Reed J, Miyashita T, Maria Ibrado A, Huang Y, Bhalla K.
    Clin Cancer Res; 1995 May 15; 1(5):559-64. PubMed ID: 9816016
    [Abstract] [Full Text] [Related]

  • 10. Mcl-1 is downregulated in cisplatin-induced apoptosis, and proteasome inhibitors restore Mcl-1 and promote survival in renal tubular epithelial cells.
    Yang C, Kaushal V, Shah SV, Kaushal GP.
    Am J Physiol Renal Physiol; 2007 Jun 15; 292(6):F1710-7. PubMed ID: 17311906
    [Abstract] [Full Text] [Related]

  • 11. The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in multiple myeloma cells through transcriptional repression and down-regulation of Mcl-1.
    Gojo I, Zhang B, Fenton RG.
    Clin Cancer Res; 2002 Nov 15; 8(11):3527-38. PubMed ID: 12429644
    [Abstract] [Full Text] [Related]

  • 12. LncRNA H19 overexpression induces bortezomib resistance in multiple myeloma by targeting MCL-1 via miR-29b-3p.
    Pan Y, Zhang Y, Liu W, Huang Y, Shen X, Jing R, Pu J, Wang X, Ju S, Cong H, Chen H.
    Cell Death Dis; 2019 Feb 06; 10(2):106. PubMed ID: 30728351
    [Abstract] [Full Text] [Related]

  • 13. Clitocine targets Mcl-1 to induce drug-resistant human cancer cell apoptosis in vitro and tumor growth inhibition in vivo.
    Sun JG, Li H, Li X, Zeng X, Wu P, Fung KP, Liu FY.
    Apoptosis; 2014 May 06; 19(5):871-82. PubMed ID: 24563182
    [Abstract] [Full Text] [Related]

  • 14. Circumvention of Mcl-1-dependent drug resistance by simultaneous Chk1 and MEK1/2 inhibition in human multiple myeloma cells.
    Pei XY, Dai Y, Felthousen J, Chen S, Takabatake Y, Zhou L, Youssefian LE, Sanderson MW, Bodie WW, Kramer LB, Orlowski RZ, Grant S.
    PLoS One; 2014 May 06; 9(3):e89064. PubMed ID: 24594907
    [Abstract] [Full Text] [Related]

  • 15. Arylazopyrazole AAP1742 inhibits CDKs and induces apoptosis in multiple myeloma cells via Mcl-1 downregulation.
    Jorda R, Navrátilová J, Hušková Z, Schütznerová E, Cankař P, Strnad M, Kryštof V.
    Chem Biol Drug Des; 2014 Oct 06; 84(4):402-8. PubMed ID: 24803299
    [Abstract] [Full Text] [Related]

  • 16. Caspase-dependent Mcl-1 cleavage and effect of Mcl-1 phosphorylation in ABT-737-induced apoptosis in human acute lymphoblastic leukemia cell lines.
    Ryu Y, Hall CP, Reynolds CP, Kang MH.
    Exp Biol Med (Maywood); 2014 Oct 06; 239(10):1390-402. PubMed ID: 24951472
    [Abstract] [Full Text] [Related]

  • 17. miR-137 and miR-197 Induce Apoptosis and Suppress Tumorigenicity by Targeting MCL-1 in Multiple Myeloma.
    Yang Y, Li F, Saha MN, Abdi J, Qiu L, Chang H.
    Clin Cancer Res; 2015 May 15; 21(10):2399-411. PubMed ID: 25724519
    [Abstract] [Full Text] [Related]

  • 18. Inhibiting the mTOR pathway synergistically enhances cytotoxicity in ovarian cancer cells induced by etoposide through upregulation of c-Jun.
    Itamochi H, Oishi T, Shimada M, Sato S, Uegaki K, Naniwa J, Sato S, Nonaka M, Terakawa N, Kigawa J, Harada T.
    Clin Cancer Res; 2011 Jul 15; 17(14):4742-50. PubMed ID: 21610153
    [Abstract] [Full Text] [Related]

  • 19. Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation.
    Kang MH, Wan Z, Kang YH, Sposto R, Reynolds CP.
    J Natl Cancer Inst; 2008 Apr 16; 100(8):580-95. PubMed ID: 18398104
    [Abstract] [Full Text] [Related]

  • 20. Upregulation of Mcl-1 inhibits JQ1-triggered anticancer activity in hepatocellular carcinoma cells.
    Zhang HP, Li GQ, Zhang Y, Guo WZ, Zhang JK, Li J, Lv JF, Zhang SJ.
    Biochem Biophys Res Commun; 2018 Jan 22; 495(4):2456-2461. PubMed ID: 29287727
    [Abstract] [Full Text] [Related]

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