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281 related items for PubMed ID: 24126433
21. Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells. Mérino D, Khaw SL, Glaser SP, Anderson DJ, Belmont LD, Wong C, Yue P, Robati M, Phipson B, Fairlie WD, Lee EF, Campbell KJ, Vandenberg CJ, Cory S, Roberts AW, Ludlam MJ, Huang DC, Bouillet P. Blood; 2012 Jun 14; 119(24):5807-16. PubMed ID: 22538851 [Abstract] [Full Text] [Related]
22. ABT-737 induces apoptosis in mantle cell lymphoma cells with a Bcl-2high/Mcl-1low profile and synergizes with other antineoplastic agents. Touzeau C, Dousset C, Bodet L, Gomez-Bougie P, Bonnaud S, Moreau A, Moreau P, Pellat-Deceunynck C, Amiot M, Le Gouill S. Clin Cancer Res; 2011 Sep 15; 17(18):5973-81. PubMed ID: 21821698 [Abstract] [Full Text] [Related]
23. Targeting CDK9 by wogonin and related natural flavones potentiates the anti-cancer efficacy of the Bcl-2 family inhibitor ABT-263. Polier G, Giaisi M, Köhler R, Müller WW, Lutz C, Buss EC, Krammer PH, Li-Weber M. Int J Cancer; 2015 Feb 01; 136(3):688-98. PubMed ID: 24895203 [Abstract] [Full Text] [Related]
24. Metastatic SW620 colon cancer cells are primed for death when detached and can be sensitized to anoikis by the BH3-mimetic ABT-737. Maamer-Azzabi A, Ndozangue-Touriguine O, Bréard J. Cell Death Dis; 2013 Sep 12; 4(9):e801. PubMed ID: 24030153 [Abstract] [Full Text] [Related]
25. Downregulation of MCL-1 and upregulation of PUMA using mTOR inhibitors enhance antitumor efficacy of BH3 mimetics in triple-negative breast cancer. Li H, Liu L, Chang H, Zou Z, Xing D. Cell Death Dis; 2018 Jan 26; 9(2):137. PubMed ID: 29374168 [Abstract] [Full Text] [Related]
27. Clitocine induces apoptosis and enhances the lethality of ABT-737 in human colon cancer cells by disrupting the interaction of Mcl-1 and Bak. Sun JG, Xiang J, Zeng XL, Li X, Wu P, Fung KP, Liu FY. Cancer Lett; 2014 Dec 28; 355(2):253-63. PubMed ID: 25304383 [Abstract] [Full Text] [Related]
29. PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim. Park SH, Ito K, Olcott W, Katsyv I, Halstead-Nussloch G, Irie HY. Breast Cancer Res; 2015 Jun 19; 17(1):86. PubMed ID: 26084280 [Abstract] [Full Text] [Related]
31. Dihydroartemisinin suppresses STAT3 signaling and Mcl-1 and Survivin expression to potentiate ABT-263-induced apoptosis in Non-small Cell Lung Cancer cells harboring EGFR or RAS mutation. Yan X, Li P, Zhan Y, Qi M, Liu J, An Z, Yang W, Xiao H, Wu H, Qi Y, Shao H. Biochem Pharmacol; 2018 Apr 13; 150():72-85. PubMed ID: 29360439 [Abstract] [Full Text] [Related]
32. Targeting ERK1/2-bim signaling cascades by BH3-mimetic ABT-737 as an alternative therapeutic strategy for oral cancer. Shin JA, Kim LH, Lee SJ, Jeong JH, Jung JY, Lee HN, Hong IS, Cho SD. Oncotarget; 2015 Nov 03; 6(34):35667-83. PubMed ID: 26447615 [Abstract] [Full Text] [Related]
33. Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1. Yecies D, Carlson NE, Deng J, Letai A. Blood; 2010 Apr 22; 115(16):3304-13. PubMed ID: 20197552 [Abstract] [Full Text] [Related]
34. Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737. Tahir SK, Yang X, Anderson MG, Morgan-Lappe SE, Sarthy AV, Chen J, Warner RB, Ng SC, Fesik SW, Elmore SW, Rosenberg SH, Tse C. Cancer Res; 2007 Feb 01; 67(3):1176-83. PubMed ID: 17283153 [Abstract] [Full Text] [Related]
35. Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia. Ma J, Zhao S, Qiao X, Knight T, Edwards H, Polin L, Kushner J, Dzinic SH, White K, Wang G, Zhao L, Lin H, Wang Y, Taub JW, Ge Y. Clin Cancer Res; 2019 Nov 15; 25(22):6815-6826. PubMed ID: 31320594 [Abstract] [Full Text] [Related]
36. Metformin Synergizes with BCL-XL/BCL-2 Inhibitor ABT-263 to Induce Apoptosis Specifically in p53-Defective Cancer Cells. Li X, Li B, Ni Z, Zhou P, Wang B, He J, Xiong H, Yang F, Wu Y, Lyu X, Zhang Y, Zeng Y, Lian J, He F. Mol Cancer Ther; 2017 Sep 15; 16(9):1806-1818. PubMed ID: 28533436 [Abstract] [Full Text] [Related]
37. Inhibition of phosphatidylinositol 3-kinase/AKT signaling by NVP-BKM120 promotes ABT-737-induced toxicity in a caspase-dependent manner through mitochondrial dysfunction and DNA damage response in established and primary cultured glioblastoma cells. Jane EP, Premkumar DR, Morales A, Foster KA, Pollack IF. J Pharmacol Exp Ther; 2014 Jul 15; 350(1):22-35. PubMed ID: 24741074 [Abstract] [Full Text] [Related]
38. Flavopiridol enhances ABT-199 sensitivity in unfavourable-risk multiple myeloma cells in vitro and in vivo. Zhou L, Zhang Y, Sampath D, Leverson J, Dai Y, Kmieciak M, Nguyen M, Orlowski RZ, Grant S. Br J Cancer; 2018 Feb 06; 118(3):388-397. PubMed ID: 29241222 [Abstract] [Full Text] [Related]
39. Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells. Niu X, Zhao J, Ma J, Xie C, Edwards H, Wang G, Caldwell JT, Xiang S, Zhang X, Chu R, Wang ZJ, Lin H, Taub JW, Ge Y. Clin Cancer Res; 2016 Sep 01; 22(17):4440-51. PubMed ID: 27103402 [Abstract] [Full Text] [Related]