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499 related items for PubMed ID: 24139940

  • 1. Design and synthesis of silicon-containing tubulin polymerization inhibitors: replacement of the ethylene moiety of combretastatin A-4 with a silicon linker.
    Nakamura M, Kajita D, Matsumoto Y, Hashimoto Y.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7381-91. PubMed ID: 24139940
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and antitumor-evaluation of cyclopropyl-containing combretastatin analogs.
    Fürst R, Zupkó I, Berényi A, Ecker GF, Rinner U.
    Bioorg Med Chem Lett; 2009 Dec 15; 19(24):6948-51. PubMed ID: 19879758
    [Abstract] [Full Text] [Related]

  • 4. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
    Chang JY, Yang MF, Chang CY, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Oct 19; 49(21):6412-5. PubMed ID: 17034147
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis, biological evaluation and molecular modeling of 1,3,4-oxadiazoline analogs of combretastatin-A4 as novel antitubulin agents.
    Hu Y, Lu X, Chen K, Yan R, Li QS, Zhu HL.
    Bioorg Med Chem; 2012 Jan 15; 20(2):903-9. PubMed ID: 22192936
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.
    Sun J, Chen L, Liu C, Wang Z, Zuo D, Pan J, Qi H, Bao K, Wu Y, Zhang W.
    Chem Biol Drug Des; 2015 Dec 15; 86(6):1541-7. PubMed ID: 26202587
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, biological evaluation and molecular docking studies of resveratrol derivatives possessing curcumin moiety as potent antitubulin agents.
    Ruan BF, Lu X, Li TT, Tang JF, Wei Y, Wang XL, Zheng SL, Yao RS, Zhu HL.
    Bioorg Med Chem; 2012 Jan 15; 20(2):1113-21. PubMed ID: 22189271
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological studies of novel tubulin inhibitors.
    Sun Y, Pandit B, Chettiar SN, Etter JP, Lewis A, Johnsamuel J, Li PK.
    Bioorg Med Chem Lett; 2013 Aug 01; 23(15):4465-8. PubMed ID: 23790539
    [Abstract] [Full Text] [Related]

  • 9. Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect.
    Ibrahim TS, Hawwas MM, Malebari AM, Taher ES, Omar AM, Neamatallah T, Abdel-Samii ZK, Safo MK, Elshaier YAMM.
    J Enzyme Inhib Med Chem; 2021 Dec 01; 36(1):802-818. PubMed ID: 33730937
    [Abstract] [Full Text] [Related]

  • 10. Potent combretastatin A-4 analogs containing 1,2,4-triazole: Synthesis, antiproliferative, anti-tubulin activity, and docking study.
    Mustafa M, Anwar S, Elgamal F, Ahmed ER, Aly OM.
    Eur J Med Chem; 2019 Dec 01; 183():111697. PubMed ID: 31536891
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis, biological evaluation and cocrystal structures with tubulin of chiral β-lactam bridged combretastatin A-4 analogues as potent antitumor agents.
    Zhou P, Liang Y, Zhang H, Jiang H, Feng K, Xu P, Wang J, Wang X, Ding K, Luo C, Liu M, Wang Y.
    Eur J Med Chem; 2018 Jan 20; 144():817-842. PubMed ID: 29306206
    [Abstract] [Full Text] [Related]

  • 12. A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors.
    Barnes NG, Parker AW, Ahmed Mal Ullah AA, Ragazzon PA, Hadfield JA.
    Bioorg Med Chem; 2020 Oct 01; 28(19):115684. PubMed ID: 32912434
    [Abstract] [Full Text] [Related]

  • 13. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C, Sathish M, Anchi P, Tokala R, Lakshmi UJ, Reddy VG, Shankaraiah N, Godugu C, Kamal A.
    ChemMedChem; 2019 Dec 17; 14(24):2052-2060. PubMed ID: 31674147
    [Abstract] [Full Text] [Related]

  • 14. Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents.
    Duan YT, Man RJ, Tang DJ, Yao YF, Tao XX, Yu C, Liang XY, Makawana JA, Zou MJ, Wang ZC, Zhu HL.
    Sci Rep; 2016 May 03; 6():25387. PubMed ID: 27138035
    [Abstract] [Full Text] [Related]

  • 15. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 03; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 16. Novel Combretastatin A-4 Analogs-Design, Synthesis, and Antiproliferative and Anti-Tubulin Activity.
    Jędrzejczyk M, Morabito B, Żyżyńska-Granica B, Struga M, Janczak J, Aminpour M, Tuszynski JA, Huczyński A.
    Molecules; 2024 May 08; 29(10):. PubMed ID: 38792062
    [Abstract] [Full Text] [Related]

  • 17. Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues.
    Theeramunkong S, Caldarelli A, Massarotti A, Aprile S, Caprioglio D, Zaninetti R, Teruggi A, Pirali T, Grosa G, Tron GC, Genazzani AA.
    J Med Chem; 2011 Jul 28; 54(14):4977-86. PubMed ID: 21696175
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
    Penthala NR, Zong H, Ketkar A, Madadi NR, Janganati V, Eoff RL, Guzman ML, Crooks PA.
    Eur J Med Chem; 2015 Mar 06; 92():212-20. PubMed ID: 25557492
    [Abstract] [Full Text] [Related]

  • 19. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors.
    Nien CY, Chen YC, Kuo CC, Hsieh HP, Chang CY, Wu JS, Wu SY, Liou JP, Chang JY.
    J Med Chem; 2010 Mar 11; 53(5):2309-13. PubMed ID: 20148562
    [Abstract] [Full Text] [Related]

  • 20. 5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2.
    Lee HY, Chang JY, Nien CY, Kuo CC, Shih KH, Wu CH, Chang CY, Lai WY, Liou JP.
    J Med Chem; 2011 Dec 22; 54(24):8517-25. PubMed ID: 22060033
    [Abstract] [Full Text] [Related]

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