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201 related items for PubMed ID: 24146961

  • 1. Digitoflavone inhibits IκBα kinase and enhances apoptosis induced by TNFα through downregulation of expression of nuclear factor κB-regulated gene products in human pancreatic cancer cells.
    Cai X, Lu W, Yang Y, Yang J, Ye J, Gu Z, Hu C, Wang X, Cao P.
    PLoS One; 2013; 8(10):e77126. PubMed ID: 24146961
    [Abstract] [Full Text] [Related]

  • 2. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B, Pandey MK, Aggarwal BB.
    Mol Pharmacol; 2007 Jun; 71(6):1703-14. PubMed ID: 17387141
    [Abstract] [Full Text] [Related]

  • 3. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S, Gutierrez AM, Lotan R, Aggarwal BB.
    Cancer Res; 2005 Oct 15; 65(20):9555-65. PubMed ID: 16230421
    [Abstract] [Full Text] [Related]

  • 4. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
    Takada Y, Kobayashi Y, Aggarwal BB.
    J Biol Chem; 2005 Apr 29; 280(17):17203-12. PubMed ID: 15710601
    [Abstract] [Full Text] [Related]

  • 5. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.
    Shukla S, Gupta S.
    Clin Cancer Res; 2004 May 01; 10(9):3169-78. PubMed ID: 15131058
    [Abstract] [Full Text] [Related]

  • 6. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
    Ichikawa H, Takada Y, Murakami A, Aggarwal BB.
    J Immunol; 2005 Jun 01; 174(11):7383-92. PubMed ID: 15905586
    [Abstract] [Full Text] [Related]

  • 7. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
    Shishodia S, Sethi G, Konopleva M, Andreeff M, Aggarwal BB.
    Clin Cancer Res; 2006 Mar 15; 12(6):1828-38. PubMed ID: 16551868
    [Abstract] [Full Text] [Related]

  • 8. 3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.
    Yadav VR, Prasad S, Gupta SC, Sung B, Phatak SS, Zhang S, Aggarwal BB.
    J Biol Chem; 2012 Jan 02; 287(1):245-256. PubMed ID: 22065587
    [Abstract] [Full Text] [Related]

  • 9. Indole-3-carbinol suppresses NF-kappaB and IkappaBalpha kinase activation, causing inhibition of expression of NF-kappaB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells.
    Takada Y, Andreeff M, Aggarwal BB.
    Blood; 2005 Jul 15; 106(2):641-9. PubMed ID: 15811958
    [Abstract] [Full Text] [Related]

  • 10. Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion.
    Takada Y, Murakami A, Aggarwal BB.
    Oncogene; 2005 Oct 20; 24(46):6957-69. PubMed ID: 16007145
    [Abstract] [Full Text] [Related]

  • 11. Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation.
    Sethi G, Ahn KS, Pandey MK, Aggarwal BB.
    Blood; 2007 Apr 01; 109(7):2727-35. PubMed ID: 17110449
    [Abstract] [Full Text] [Related]

  • 12. Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells.
    Zhang JS, Herreros-Villanueva M, Koenig A, Deng Z, de Narvajas AA, Gomez TS, Meng X, Bujanda L, Ellenrieder V, Li XK, Kaufmann SH, Billadeau DD.
    Cell Death Dis; 2014 Mar 27; 5(3):e1142. PubMed ID: 24675460
    [Abstract] [Full Text] [Related]

  • 13. Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis.
    Kunnumakkara AB, Nair AS, Ahn KS, Pandey MK, Yi Z, Liu M, Aggarwal BB.
    Blood; 2007 Jun 15; 109(12):5112-21. PubMed ID: 17332240
    [Abstract] [Full Text] [Related]

  • 14. Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor.
    Takada Y, Fang X, Jamaluddin MS, Boyd DD, Aggarwal BB.
    J Biol Chem; 2004 Sep 17; 279(38):39541-54. PubMed ID: 15252041
    [Abstract] [Full Text] [Related]

  • 15. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S, Ichikawa H, Takada Y, Sandur SK, Shishodia S, Aggarwal BB.
    Mol Pharmacol; 2006 Jan 17; 69(1):195-206. PubMed ID: 16219905
    [Abstract] [Full Text] [Related]

  • 16. β-Caryophyllene oxide potentiates TNFα-induced apoptosis and inhibits invasion through down-modulation of NF-κB-regulated gene products.
    Kim C, Cho SK, Kim KD, Nam D, Chung WS, Jang HJ, Lee SG, Shim BS, Sethi G, Ahn KS.
    Apoptosis; 2014 Apr 17; 19(4):708-18. PubMed ID: 24370994
    [Abstract] [Full Text] [Related]

  • 17. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G, Ahn KS, Sung B, Aggarwal BB.
    Mol Cancer Ther; 2008 Jun 17; 7(6):1604-14. PubMed ID: 18566231
    [Abstract] [Full Text] [Related]

  • 18. Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.
    Takada Y, Ichikawa H, Pataer A, Swisher S, Aggarwal BB.
    Oncogene; 2007 Feb 22; 26(8):1201-12. PubMed ID: 16924232
    [Abstract] [Full Text] [Related]

  • 19. PMS1077 sensitizes TNF-α induced apoptosis in human prostate cancer cells by blocking NF-κB signaling pathway.
    Shi J, Chen J, Serradji N, Xu X, Zhou H, Ma Y, Sun Z, Jiang P, Du Y, Yang J, Dong C, Wang Q.
    PLoS One; 2013 Feb 22; 8(4):e61132. PubMed ID: 23593410
    [Abstract] [Full Text] [Related]

  • 20. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
    Kunnumakkara AB, Ichikawa H, Anand P, Mohankumar CJ, Hema PS, Nair MS, Aggarwal BB.
    Mol Cancer Ther; 2008 Oct 22; 7(10):3306-17. PubMed ID: 18852134
    [Abstract] [Full Text] [Related]

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