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Journal Abstract Search

359 related items for PubMed ID: 24148991

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  • 6. 4-Aminoquinoline derivatives as novel Mycobacterium tuberculosis GyrB inhibitors: Structural optimization, synthesis and biological evaluation.
    Medapi B, Suryadevara P, Renuka J, Sridevi JP, Yogeeswari P, Sriram D.
    Eur J Med Chem; 2015 Oct 20; 103():1-16. PubMed ID: 26318054
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  • 7. Development of acridine derivatives as selective Mycobacterium tuberculosis DNA gyrase inhibitors.
    Medapi B, Meda N, Kulkarni P, Yogeeswari P, Sriram D.
    Bioorg Med Chem; 2016 Feb 15; 24(4):877-85. PubMed ID: 26787274
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  • 8. Exploring the gyrase ATPase domain for tailoring newer anti-tubercular drugs: hit to lead optimization of a novel class of thiazole inhibitors.
    Jeankumar VU, Kotagiri S, Janupally R, Suryadevara P, Sridevi JP, Medishetti R, Kulkarni P, Yogeeswari P, Sriram D.
    Bioorg Med Chem; 2015 Feb 01; 23(3):588-601. PubMed ID: 25541204
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  • 10. Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy.
    Kale RR, Kale MG, Waterson D, Raichurkar A, Hameed SP, Manjunatha MR, Kishore Reddy BK, Malolanarasimhan K, Shinde V, Koushik K, Jena LK, Menasinakai S, Humnabadkar V, Madhavapeddi P, Basavarajappa H, Sharma S, Nandishaiah R, Mahesh Kumar KN, Ganguly S, Ahuja V, Gaonkar S, Naveen Kumar CN, Ogg D, Boriack-Sjodin PA, Sambandamurthy VK, de Sousa SM, Ghorpade SR.
    Bioorg Med Chem Lett; 2014 Feb 01; 24(3):870-9. PubMed ID: 24405701
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  • 11. Design, synthesis and antitubercular activity of 4-alkoxy-triazoloquinolones able to inhibit the M. tuberculosis DNA gyrase.
    Carta A, Bua A, Corona P, Piras S, Briguglio I, Molicotti P, Zanetti S, Laurini E, Aulic S, Fermeglia M, Pricl S.
    Eur J Med Chem; 2019 Jan 01; 161():399-415. PubMed ID: 30384044
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  • 12. Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase B.
    Kale MG, Raichurkar A, P SH, Waterson D, McKinney D, Manjunatha MR, Kranthi U, Koushik K, Jena Lk, Shinde V, Rudrapatna S, Barde S, Humnabadkar V, Madhavapeddi P, Basavarajappa H, Ghosh A, Ramya VK, Guptha S, Sharma S, Vachaspati P, Kumar KN, Giridhar J, Reddy J, Panduga V, Ganguly S, Ahuja V, Gaonkar S, Kumar CN, Ogg D, Tucker JA, Boriack-Sjodin PA, de Sousa SM, Sambandamurthy VK, Ghorpade SR.
    J Med Chem; 2013 Nov 14; 56(21):8834-48. PubMed ID: 24088190
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  • 14. Enabling the (3 + 2) cycloaddition reaction in assembling newer anti-tubercular lead acting through the inhibition of the gyrase ATPase domain: lead optimization and structure activity profiling.
    Jeankumar VU, Reshma RS, Janupally R, Saxena S, Sridevi JP, Medapi B, Kulkarni P, Yogeeswari P, Sriram D.
    Org Biomol Chem; 2015 Feb 28; 13(8):2423-31. PubMed ID: 25569565
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  • 15. Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.
    Hameed P S, Patil V, Solapure S, Sharma U, Madhavapeddi P, Raichurkar A, Chinnapattu M, Manjrekar P, Shanbhag G, Puttur J, Shinde V, Menasinakai S, Rudrapatana S, Achar V, Awasthy D, Nandishaiah R, Humnabadkar V, Ghosh A, Narayan C, Ramya VK, Kaur P, Sharma S, Werngren J, Hoffner S, Panduga V, Kumar CN, Reddy J, Kumar K N M, Ganguly S, Bharath S, Bheemarao U, Mukherjee K, Arora U, Gaonkar S, Coulson M, Waterson D, Sambandamurthy VK, de Sousa SM.
    J Med Chem; 2014 Jun 12; 57(11):4889-905. PubMed ID: 24809953
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  • 16. Replacement of cardiotoxic aminopiperidine linker with piperazine moiety reduces cardiotoxicity? Mycobacterium tuberculosis novel bacterial topoisomerase inhibitors.
    Bobesh KA, Renuka J, Srilakshmi RR, Yellanki S, Kulkarni P, Yogeeswari P, Sriram D.
    Bioorg Med Chem; 2016 Jan 01; 24(1):42-52. PubMed ID: 26678175
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  • 17. Development of 2-amino-5-phenylthiophene-3-carboxamide derivatives as novel inhibitors of Mycobacterium tuberculosis DNA GyrB domain.
    Saxena S, Samala G, Renuka J, Sridevi JP, Yogeeswari P, Sriram D.
    Bioorg Med Chem; 2015 Apr 01; 23(7):1402-12. PubMed ID: 25766629
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  • 18. Novel anti-tubercular and antibacterial based benzosuberone-thiazole moieties: Synthesis, molecular docking analysis, DNA gyrase supercoiling and ATPase activity.
    Omar MA, Masaret GS, Abbas EMH, Abdel-Aziz MM, Harras MF, Farghaly TA.
    Bioorg Chem; 2020 Nov 01; 104():104316. PubMed ID: 33022549
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  • 19. Aminopyrazinamides: novel and specific GyrB inhibitors that kill replicating and nonreplicating Mycobacterium tuberculosis.
    Shirude PS, Madhavapeddi P, Tucker JA, Murugan K, Patil V, Basavarajappa H, Raichurkar AV, Humnabadkar V, Hussein S, Sharma S, Ramya VK, Narayan CB, Balganesh TS, Sambandamurthy VK.
    ACS Chem Biol; 2013 Mar 15; 8(3):519-23. PubMed ID: 23268609
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  • 20. Gyrase ATPase domain as an antitubercular drug discovery platform: structure-based design and lead optimization of nitrothiazolyl carboxamide analogues.
    Jeankumar VU, Renuka J, Kotagiri S, Saxena S, Kakan SS, Sridevi JP, Yellanki S, Kulkarni P, Yogeeswari P, Sriram D.
    ChemMedChem; 2014 Aug 15; 9(8):1850-9. PubMed ID: 24962352
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