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137 related items for PubMed ID: 24157364

  • 1. Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain.
    Pirazzini M, Henke T, Rossetto O, Mahrhold S, Krez N, Rummel A, Montecucco C, Binz T.
    FEBS Lett; 2013 Nov 29; 587(23):3831-6. PubMed ID: 24157364
    [Abstract] [Full Text] [Related]

  • 2. Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.
    Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.
    Toxicon; 2013 Dec 01; 75():108-21. PubMed ID: 23817019
    [Abstract] [Full Text] [Related]

  • 3. Exchange of the H(CC) domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin.
    Rummel A, Mahrhold S, Bigalke H, Binz T.
    FEBS J; 2011 Dec 01; 278(23):4506-15. PubMed ID: 21624052
    [Abstract] [Full Text] [Related]

  • 4. Synchronized chaperone function of botulinum neurotoxin domains mediates light chain translocation into neurons.
    Fischer A.
    Curr Top Microbiol Immunol; 2013 Dec 01; 364():115-37. PubMed ID: 23239351
    [Abstract] [Full Text] [Related]

  • 5. Novel chimeras of botulinum and tetanus neurotoxins yield insights into their distinct sites of neuroparalysis.
    Wang J, Zurawski TH, Meng J, Lawrence GW, Aoki KR, Wheeler L, Dolly JO.
    FASEB J; 2012 Dec 01; 26(12):5035-48. PubMed ID: 22942075
    [Abstract] [Full Text] [Related]

  • 6. Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
    Strotmeier J, Lee K, Völker AK, Mahrhold S, Zong Y, Zeiser J, Zhou J, Pich A, Bigalke H, Binz T, Rummel A, Jin R.
    Biochem J; 2010 Oct 15; 431(2):207-16. PubMed ID: 20704566
    [Abstract] [Full Text] [Related]

  • 7. Translocation of botulinum neurotoxin light chain protease through the heavy chain channel.
    Koriazova LK, Montal M.
    Nat Struct Biol; 2003 Jan 15; 10(1):13-8. PubMed ID: 12459720
    [Abstract] [Full Text] [Related]

  • 8. Moving across membranes.
    Neale EA.
    Nat Struct Biol; 2003 Jan 15; 10(1):2-3. PubMed ID: 12490883
    [Abstract] [Full Text] [Related]

  • 9. Double receptor anchorage of botulinum neurotoxins accounts for their exquisite neurospecificity.
    Rummel A.
    Curr Top Microbiol Immunol; 2013 Jan 15; 364():61-90. PubMed ID: 23239349
    [Abstract] [Full Text] [Related]

  • 10. Targeted delivery into motor nerve terminals of inhibitors for SNARE-cleaving proteases via liposomes coupled to an atoxic botulinum neurotoxin.
    Edupuganti OP, Ovsepian SV, Wang J, Zurawski TH, Schmidt JJ, Smith L, Lawrence GW, Dolly JO.
    FEBS J; 2012 Jul 15; 279(14):2555-67. PubMed ID: 22607388
    [Abstract] [Full Text] [Related]

  • 11. Longer-acting and highly potent chimaeric inhibitors of excessive exocytosis created with domains from botulinum neurotoxin A and B.
    Wang J, Zurawski TH, Bodeker MO, Meng J, Boddul S, Aoki KR, Dolly JO.
    Biochem J; 2012 May 15; 444(1):59-67. PubMed ID: 22360156
    [Abstract] [Full Text] [Related]

  • 12. Structure and activity of a functional derivative of Clostridium botulinum neurotoxin B.
    Masuyer G, Beard M, Cadd VA, Chaddock JA, Acharya KR.
    J Struct Biol; 2011 Apr 15; 174(1):52-7. PubMed ID: 21078393
    [Abstract] [Full Text] [Related]

  • 13. Botulinum neurotoxin type D enables cytosolic delivery of enzymatically active cargo proteins to neurones via unfolded translocation intermediates.
    Bade S, Rummel A, Reisinger C, Karnath T, Ahnert-Hilger G, Bigalke H, Binz T.
    J Neurochem; 2004 Dec 15; 91(6):1461-72. PubMed ID: 15584922
    [Abstract] [Full Text] [Related]

  • 14. Role of metals in the biological activity of Clostridium botulinum neurotoxins.
    Eswaramoorthy S, Kumaran D, Keller J, Swaminathan S.
    Biochemistry; 2004 Mar 02; 43(8):2209-16. PubMed ID: 14979717
    [Abstract] [Full Text] [Related]

  • 15. Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.
    Jin R, Rummel A, Binz T, Brunger AT.
    Nature; 2006 Dec 21; 444(7122):1092-5. PubMed ID: 17167421
    [Abstract] [Full Text] [Related]

  • 16. Single molecule detection of intermediates during botulinum neurotoxin translocation across membranes.
    Fischer A, Montal M.
    Proc Natl Acad Sci U S A; 2007 Jun 19; 104(25):10447-52. PubMed ID: 17563359
    [Abstract] [Full Text] [Related]

  • 17. The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction.
    Rummel A, Mahrhold S, Bigalke H, Binz T.
    Mol Microbiol; 2004 Feb 19; 51(3):631-43. PubMed ID: 14731268
    [Abstract] [Full Text] [Related]

  • 18. Double anchorage to the membrane and intact inter-chain disulfide bond are required for the low pH induced entry of tetanus and botulinum neurotoxins into neurons.
    Pirazzini M, Rossetto O, Bolognese P, Shone CC, Montecucco C.
    Cell Microbiol; 2011 Nov 19; 13(11):1731-43. PubMed ID: 21790947
    [Abstract] [Full Text] [Related]

  • 19. Fusion of Golgi-derived vesicles mediated by SNAP-25 is essential for sympathetic neuron outgrowth but relatively insensitive to botulinum neurotoxins in vitro.
    Lawrence GW, Wang J, Brin MF, Aoki KR, Wheeler L, Dolly JO.
    FEBS J; 2014 Jul 19; 281(14):3243-60. PubMed ID: 24863955
    [Abstract] [Full Text] [Related]

  • 20. Time course and temperature dependence of the membrane translocation of tetanus and botulinum neurotoxins C and D in neurons.
    Pirazzini M, Rossetto O, Bertasio C, Bordin F, Shone CC, Binz T, Montecucco C.
    Biochem Biophys Res Commun; 2013 Jan 04; 430(1):38-42. PubMed ID: 23200837
    [Abstract] [Full Text] [Related]

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