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Journal Abstract Search

144 related items for PubMed ID: 24164572

  • 21. Adverse effects of dipeptidyl peptidases 8 and 9 inhibition in rodents revisited.
    Burkey BF, Hoffmann PK, Hassiepen U, Trappe J, Juedes M, Foley JE.
    Diabetes Obes Metab; 2008 Nov; 10(11):1057-61. PubMed ID: 18422675
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  • 22. Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.
    Gómez-Lechón MJ, Castell JV, Donato MT.
    Chem Biol Interact; 2007 May 20; 168(1):30-50. PubMed ID: 17134688
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  • 23. Target-mediated metabolism and target-mediated drug disposition of the DPPIV inhibitor AMG 222.
    Greene RJ, Tu H, Gibbs JP, Greg Slatter J.
    Xenobiotica; 2011 Nov 20; 41(11):945-57. PubMed ID: 21867423
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  • 24. Improved detection of reactive metabolites with a bromine-containing glutathione analog using mass defect and isotope pattern matching.
    Leblanc A, Shiao TC, Roy R, Sleno L.
    Rapid Commun Mass Spectrom; 2010 May 15; 24(9):1241-50. PubMed ID: 20391594
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  • 25. Long-term chronic toxicity testing using human pluripotent stem cell-derived hepatocytes.
    Holmgren G, Sjögren AK, Barragan I, Sabirsh A, Sartipy P, Synnergren J, Björquist P, Ingelman-Sundberg M, Andersson TB, Edsbagge J.
    Drug Metab Dispos; 2014 Sep 15; 42(9):1401-6. PubMed ID: 24980256
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  • 26. Metabolites and safety: What are the concerns, and how should we address them?
    Smith DA, Obach RS.
    Chem Res Toxicol; 2006 Dec 15; 19(12):1570-9. PubMed ID: 17173370
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  • 27. The role of leukocyte-generated reactive metabolites in the pathogenesis of idiosyncratic drug reactions.
    Uetrecht JP.
    Drug Metab Rev; 1992 Dec 15; 24(3):299-366. PubMed ID: 1628536
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  • 30. Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolites.
    Wang WW, Khetani SR, Krzyzewski S, Duignan DB, Obach RS.
    Drug Metab Dispos; 2010 Oct 15; 38(10):1900-5. PubMed ID: 20595376
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  • 32. Absorption, metabolism, and excretion of [14C]vildagliptin, a novel dipeptidyl peptidase 4 inhibitor, in humans.
    He H, Tran P, Yin H, Smith H, Batard Y, Wang L, Einolf H, Gu H, Mangold JB, Fischer V, Howard D.
    Drug Metab Dispos; 2009 Mar 15; 37(3):536-44. PubMed ID: 19074975
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  • 34. Protocols of in vitro protein covalent binding studies in liver.
    Lévesque JF, Day SH, Jones AN.
    Methods Mol Biol; 2011 Mar 15; 691():283-301. PubMed ID: 20972760
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  • 36. Improving drug candidates by design: a focus on physicochemical properties as a means of improving compound disposition and safety.
    Meanwell NA.
    Chem Res Toxicol; 2011 Sep 19; 24(9):1420-56. PubMed ID: 21790149
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  • 38. Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes.
    Fukuda H, Ohashi R, Tsuda-Tsukimoto M, Tamai I.
    Drug Metab Dispos; 2008 Jul 19; 36(7):1275-82. PubMed ID: 18388177
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