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140 related items for PubMed ID: 24173962

  • 1. Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells.
    Zhao X, Nogawa A, Matsunaga T, Takegami T, Nakagawa H, Ishigaki Y.
    Int J Oncol; 2014 Jan; 44(1):222-8. PubMed ID: 24173962
    [Abstract] [Full Text] [Related]

  • 2. Structures of SMG1-UPFs complexes: SMG1 contributes to regulate UPF2-dependent activation of UPF1 in NMD.
    Melero R, Uchiyama A, Castaño R, Kataoka N, Kurosawa H, Ohno S, Yamashita A, Llorca O.
    Structure; 2014 Aug 05; 22(8):1105-1119. PubMed ID: 25002321
    [Abstract] [Full Text] [Related]

  • 3. CK2-mediated TEL2 phosphorylation augments nonsense-mediated mRNA decay (NMD) by increase of SMG1 stability.
    Ahn S, Kim J, Hwang J.
    Biochim Biophys Acta; 2013 Oct 05; 1829(10):1047-55. PubMed ID: 23831331
    [Abstract] [Full Text] [Related]

  • 4. Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways.
    Metze S, Herzog VA, Ruepp MD, Mühlemann O.
    RNA; 2013 Oct 05; 19(10):1432-48. PubMed ID: 23962664
    [Abstract] [Full Text] [Related]

  • 5. Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex.
    López-Perrote A, Castaño R, Melero R, Zamarro T, Kurosawa H, Ohnishi T, Uchiyama A, Aoyagi K, Buchwald G, Kataoka N, Yamashita A, Llorca O.
    Nucleic Acids Res; 2016 Feb 29; 44(4):1909-23. PubMed ID: 26740584
    [Abstract] [Full Text] [Related]

  • 6. Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2.
    Clerici M, Deniaud A, Boehm V, Gehring NH, Schaffitzel C, Cusack S.
    Nucleic Acids Res; 2014 Feb 29; 42(4):2673-86. PubMed ID: 24271394
    [Abstract] [Full Text] [Related]

  • 7. SMG1 regulates adipogenesis via targeting of staufen1-mediated mRNA decay.
    Cho H, Han S, Park OH, Kim YK.
    Biochim Biophys Acta; 2013 Dec 29; 1829(12):1276-87. PubMed ID: 24185201
    [Abstract] [Full Text] [Related]

  • 8. The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation.
    Melero R, Hug N, López-Perrote A, Yamashita A, Cáceres JF, Llorca O.
    Nat Commun; 2016 Feb 04; 7():10585. PubMed ID: 26841701
    [Abstract] [Full Text] [Related]

  • 9. NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity.
    Chamieh H, Ballut L, Bonneau F, Le Hir H.
    Nat Struct Mol Biol; 2008 Jan 04; 15(1):85-93. PubMed ID: 18066079
    [Abstract] [Full Text] [Related]

  • 10. Processing bodies are not required for mammalian nonsense-mediated mRNA decay.
    Stalder L, Mühlemann O.
    RNA; 2009 Jul 04; 15(7):1265-73. PubMed ID: 19474145
    [Abstract] [Full Text] [Related]

  • 11. The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.
    Hug N, Cáceres JF.
    Cell Rep; 2014 Sep 25; 8(6):1845-1856. PubMed ID: 25220460
    [Abstract] [Full Text] [Related]

  • 12. Biochemical characterization of the RNA helicase UPF1 involved in nonsense-mediated mRNA decay.
    Fiorini F, Bonneau F, Le Hir H.
    Methods Enzymol; 2012 Sep 25; 511():255-74. PubMed ID: 22713324
    [Abstract] [Full Text] [Related]

  • 13. Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.
    Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S.
    Genes Dev; 2006 Feb 01; 20(3):355-67. PubMed ID: 16452507
    [Abstract] [Full Text] [Related]

  • 14. Structure of substrate-bound SMG1-8-9 kinase complex reveals molecular basis for phosphorylation specificity.
    Langer LM, Gat Y, Bonneau F, Conti E.
    Elife; 2020 May 29; 9():. PubMed ID: 32469312
    [Abstract] [Full Text] [Related]

  • 15. Upf1/Upf2 regulation of 3' untranslated region splice variants of AUF1 links nonsense-mediated and A+U-rich element-mediated mRNA decay.
    Banihashemi L, Wilson GM, Das N, Brewer G.
    Mol Cell Biol; 2006 Dec 29; 26(23):8743-54. PubMed ID: 17000771
    [Abstract] [Full Text] [Related]

  • 16. Rotaviral nonstructural protein 5 (NSP5) promotes proteasomal degradation of up-frameshift protein 1 (UPF1), a principal mediator of nonsense-mediated mRNA decay (NMD) pathway, to facilitate infection.
    Sarkar R, Banerjee S, Mukherjee A, Chawla-Sarkar M.
    Cell Signal; 2022 Jan 29; 89():110180. PubMed ID: 34718106
    [Abstract] [Full Text] [Related]

  • 17. Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways.
    Ivanov PV, Gehring NH, Kunz JB, Hentze MW, Kulozik AE.
    EMBO J; 2008 Mar 05; 27(5):736-47. PubMed ID: 18256688
    [Abstract] [Full Text] [Related]

  • 18. A highly conserved region essential for NMD in the Upf2 N-terminal domain.
    Fourati Z, Roy B, Millan C, Coureux PD, Kervestin S, van Tilbeurgh H, He F, Usón I, Jacobson A, Graille M.
    J Mol Biol; 2014 Nov 11; 426(22):3689-3702. PubMed ID: 25277656
    [Abstract] [Full Text] [Related]

  • 19. CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells.
    Hosoda N, Kim YK, Lejeune F, Maquat LE.
    Nat Struct Mol Biol; 2005 Oct 11; 12(10):893-901. PubMed ID: 16186820
    [Abstract] [Full Text] [Related]

  • 20. Phosphorylation of the N- and C-terminal UPF1 domains plays a critical role in plant nonsense-mediated mRNA decay.
    Kerényi F, Wawer I, Sikorski PJ, Kufel J, Silhavy D.
    Plant J; 2013 Dec 11; 76(5):836-48. PubMed ID: 24118551
    [Abstract] [Full Text] [Related]

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