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Journal Abstract Search

249 related items for PubMed ID: 24180432

  • 1. Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.
    Corton JC, Cunningham ML, Hummer BT, Lau C, Meek B, Peters JM, Popp JA, Rhomberg L, Seed J, Klaunig JE.
    Crit Rev Toxicol; 2014 Jan; 44(1):1-49. PubMed ID: 24180432
    [Abstract] [Full Text] [Related]

  • 2. The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions.
    Corton JC, Peters JM, Klaunig JE.
    Arch Toxicol; 2018 Jan; 92(1):83-119. PubMed ID: 29197930
    [Abstract] [Full Text] [Related]

  • 3. Rodent carcinogenicity of peroxisome proliferators and issues on human relevance.
    Lai DY.
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2004 May; 22(1):37-55. PubMed ID: 15845221
    [Abstract] [Full Text] [Related]

  • 4. A cancer risk assessment of di(2-ethylhexyl)phthalate: application of the new U.S. EPA Risk Assessment Guidelines.
    Doull J, Cattley R, Elcombe C, Lake BG, Swenberg J, Wilkinson C, Williams G, van Gemert M.
    Regul Toxicol Pharmacol; 1999 Jun; 29(3):327-57. PubMed ID: 10388618
    [Abstract] [Full Text] [Related]

  • 5. Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.
    Ren H, Aleksunes LM, Wood C, Vallanat B, George MH, Klaassen CD, Corton JC.
    Toxicol Sci; 2010 Jan; 113(1):45-59. PubMed ID: 19850644
    [Abstract] [Full Text] [Related]

  • 6. A reexamination of the PPAR-alpha activation mode of action as a basis for assessing human cancer risks of environmental contaminants.
    Guyton KZ, Chiu WA, Bateson TF, Jinot J, Scott CS, Brown RC, Caldwell JC.
    Environ Health Perspect; 2009 Nov; 117(11):1664-72. PubMed ID: 20049115
    [Abstract] [Full Text] [Related]

  • 7. Hepatic peroxisome proliferator-activated receptor α may have an important role in the toxic effects of di(2-ethylhexyl)phthalate on offspring of mice.
    Hayashi Y, Ito Y, Yamagishi N, Yanagiba Y, Tamada H, Wang D, Ramdhan DH, Naito H, Harada Y, Kamijima M, Gonzales FJ, Nakajima T.
    Toxicology; 2011 Oct 28; 289(1):1-10. PubMed ID: 21354252
    [Abstract] [Full Text] [Related]

  • 8. Comparative time course profiles of phthalate stereoisomers in mice.
    Wood CE, Jokinen MP, Johnson CL, Olson GR, Hester S, George M, Chorley BN, Carswell G, Carter JH, Wood CR, Bhat VS, Corton JC, DeAngelo AB.
    Toxicol Sci; 2014 May 28; 139(1):21-34. PubMed ID: 24496636
    [Abstract] [Full Text] [Related]

  • 9. Dose and Effect Thresholds for Early Key Events in a PPARα-Mediated Mode of Action.
    Lake AD, Wood CE, Bhat VS, Chorley BN, Carswell GK, Sey YM, Kenyon EM, Padnos B, Moore TM, Tennant AH, Schmid JE, George BJ, Ross DG, Hughes MF, Corton JC, Simmons JE, McQueen CA, Hester SD.
    Toxicol Sci; 2016 Feb 28; 149(2):312-25. PubMed ID: 26519955
    [Abstract] [Full Text] [Related]

  • 10. PPARalpha agonist-induced rodent tumors: modes of action and human relevance.
    Klaunig JE, Babich MA, Baetcke KP, Cook JC, Corton JC, David RM, DeLuca JG, Lai DY, McKee RH, Peters JM, Roberts RA, Fenner-Crisp PA.
    Crit Rev Toxicol; 2003 Feb 28; 33(6):655-780. PubMed ID: 14727734
    [Abstract] [Full Text] [Related]

  • 11. trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals.
    Maloney EK, Waxman DJ.
    Toxicol Appl Pharmacol; 1999 Dec 01; 161(2):209-18. PubMed ID: 10581215
    [Abstract] [Full Text] [Related]

  • 12. Characterization of nuclear receptor-mediated murine hepatocarcinogenesis of the herbicide pronamide and its human relevance.
    LeBaron MJ, Rasoulpour RJ, Gollapudi BB, Sura R, Kan HL, Schisler MR, Pottenger LH, Papineni S, Eisenbrandt DL.
    Toxicol Sci; 2014 Nov 01; 142(1):74-92. PubMed ID: 25092647
    [Abstract] [Full Text] [Related]

  • 13. Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome proliferator-activated receptor alpha: a review.
    Ito Y, Kamijima M, Nakajima T.
    Environ Health Prev Med; 2019 Jul 06; 24(1):47. PubMed ID: 31279339
    [Abstract] [Full Text] [Related]

  • 14. Peroxisome proliferator-activated receptor alpha protects against glomerulonephritis induced by long-term exposure to the plasticizer di-(2-ethylhexyl)phthalate.
    Kamijo Y, Hora K, Nakajima T, Kono K, Takahashi K, Ito Y, Higuchi M, Kiyosawa K, Shigematsu H, Gonzalez FJ, Aoyama T.
    J Am Soc Nephrol; 2007 Jan 06; 18(1):176-88. PubMed ID: 17135395
    [Abstract] [Full Text] [Related]

  • 15. Mono(2-ethylhexyl)phthalate and mono-n-butyl phthalate activation of peroxisome proliferator activated-receptors alpha and gamma in breast.
    Venkata NG, Robinson JA, Cabot PJ, Davis B, Monteith GR, Roberts-Thomson SJ.
    Toxicol Lett; 2006 Jun 01; 163(3):224-34. PubMed ID: 16326050
    [Abstract] [Full Text] [Related]

  • 16. Role of PPARalpha in mediating the effects of phthalates and metabolites in the liver.
    Lapinskas PJ, Brown S, Leesnitzer LM, Blanchard S, Swanson C, Cattley RC, Corton JC.
    Toxicology; 2005 Feb 01; 207(1):149-63. PubMed ID: 15590130
    [Abstract] [Full Text] [Related]

  • 17. Peroxisome proliferator-activated receptor α mediates di-(2-ethylhexyl) phthalate transgenerational repression of ovarian Esr1 expression in female mice.
    Kawano M, Qin XY, Yoshida M, Fukuda T, Nansai H, Hayashi Y, Nakajima T, Sone H.
    Toxicol Lett; 2014 Aug 04; 228(3):235-40. PubMed ID: 24811840
    [Abstract] [Full Text] [Related]

  • 18. Induction of peroxisome proliferator-activated receptor alpha (PPARalpha)-related enzymes by di(2-ethylhexyl) phthalate (DEHP) treatment in mice and rats, but not marmosets.
    Ito Y, Yamanoshita O, Kurata Y, Kamijima M, Aoyama T, Nakajima T.
    Arch Toxicol; 2007 Mar 04; 81(3):219-26. PubMed ID: 16937134
    [Abstract] [Full Text] [Related]

  • 19. Modes of action and species-specific effects of di-(2-ethylhexyl)phthalate in the liver.
    Rusyn I, Peters JM, Cunningham ML.
    Crit Rev Toxicol; 2006 May 04; 36(5):459-79. PubMed ID: 16954067
    [Abstract] [Full Text] [Related]

  • 20. Comparison of transcriptomic profiles between HFPO-DA and prototypical PPARα, PPARγ, and cytotoxic agents in mouse, rat, and pooled human hepatocytes.
    Heintz MM, Klaren WD, East AW, Haws LC, McGreal SR, Campbell RR, Thompson CM.
    Toxicol Sci; 2024 Jun 26; 200(1):165-182. PubMed ID: 38574381
    [Abstract] [Full Text] [Related]

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