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Journal Abstract Search

321 related items for PubMed ID: 24189050

  • 1. DRoP: a water analysis program identifies Ras-GTP-specific pathway of communication between membrane-interacting regions and the active site.
    Kearney BM, Johnson CW, Roberts DM, Swartz P, Mattos C.
    J Mol Biol; 2014 Feb 06; 426(3):611-29. PubMed ID: 24189050
    [Abstract] [Full Text] [Related]

  • 2. What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf.
    Filchtinski D, Sharabi O, Rüppel A, Vetter IR, Herrmann C, Shifman JM.
    J Mol Biol; 2010 Jun 11; 399(3):422-35. PubMed ID: 20361980
    [Abstract] [Full Text] [Related]

  • 3. Crystal structures of Ral-GppNHp and Ral-GDP reveal two binding sites that are also present in Ras and Rap.
    Nicely NI, Kosak J, de Serrano V, Mattos C.
    Structure; 2004 Nov 11; 12(11):2025-36. PubMed ID: 15530367
    [Abstract] [Full Text] [Related]

  • 4. Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras.
    Scheffzek K, Lautwein A, Kabsch W, Ahmadian MR, Wittinghofer A.
    Nature; 1996 Dec 12; 384(6609):591-6. PubMed ID: 8955277
    [Abstract] [Full Text] [Related]

  • 5. The structural basis for the transition from Ras-GTP to Ras-GDP.
    Hall BE, Bar-Sagi D, Nassar N.
    Proc Natl Acad Sci U S A; 2002 Sep 17; 99(19):12138-42. PubMed ID: 12213964
    [Abstract] [Full Text] [Related]

  • 6. Mechanisms of guanosine triphosphate hydrolysis by Ras and Ras-GAP proteins as rationalized by ab initio QM/MM simulations.
    Grigorenko BL, Nemukhin AV, Shadrina MS, Topol IA, Burt SK.
    Proteins; 2007 Feb 01; 66(2):456-66. PubMed ID: 17094109
    [Abstract] [Full Text] [Related]

  • 7. GTP hydrolysis mechanism of Ras-like GTPases.
    Li G, Zhang XC.
    J Mol Biol; 2004 Jul 23; 340(5):921-32. PubMed ID: 15236956
    [Abstract] [Full Text] [Related]

  • 8. High-frequency 94 GHz ENDOR characterization of the metal binding site in wild-type Ras x GDP and its oncogenic mutant G12V in frozen solution.
    Bennati M, Hertel MM, Fritscher J, Prisner TF, Weiden N, Hofweber R, Spörner M, Horn G, Kalbitzer HR.
    Biochemistry; 2006 Jan 10; 45(1):42-50. PubMed ID: 16388579
    [Abstract] [Full Text] [Related]

  • 9. Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein.
    Ito Y, Yamasaki K, Iwahara J, Terada T, Kamiya A, Shirouzu M, Muto Y, Kawai G, Yokoyama S, Laue ED, Wälchli M, Shibata T, Nishimura S, Miyazawa T.
    Biochemistry; 1997 Jul 29; 36(30):9109-19. PubMed ID: 9230043
    [Abstract] [Full Text] [Related]

  • 10. The structural basis of the activation of Ras by Sos.
    Boriack-Sjodin PA, Margarit SM, Bar-Sagi D, Kuriyan J.
    Nature; 1998 Jul 23; 394(6691):337-43. PubMed ID: 9690470
    [Abstract] [Full Text] [Related]

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  • 12. Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.
    Tong LA, de Vos AM, Milburn MV, Kim SH.
    J Mol Biol; 1991 Feb 05; 217(3):503-16. PubMed ID: 1899707
    [Abstract] [Full Text] [Related]

  • 13. The Ras-Membrane Interface: Isoform-specific Differences in The Catalytic Domain.
    Parker JA, Mattos C.
    Mol Cancer Res; 2015 Apr 05; 13(4):595-603. PubMed ID: 25566993
    [Abstract] [Full Text] [Related]

  • 14. Different structural requirements within the switch II region of the Ras protein for interactions with specific downstream targets.
    Moodie SA, Paris M, Villafranca E, Kirshmeier P, Willumsen BM, Wolfman A.
    Oncogene; 1995 Aug 03; 11(3):447-54. PubMed ID: 7630628
    [Abstract] [Full Text] [Related]

  • 15. Real-time in vitro measurement of intrinsic and Ras GAP-mediated GTP hydrolysis.
    Shutes A, Der CJ.
    Methods Enzymol; 2006 Aug 03; 407():9-22. PubMed ID: 16757310
    [Abstract] [Full Text] [Related]

  • 16. Structural and functional analysis of a mutant Ras protein that is insensitive to nitric oxide activation.
    Mott HR, Carpenter JW, Campbell SL.
    Biochemistry; 1997 Mar 25; 36(12):3640-4. PubMed ID: 9132016
    [Abstract] [Full Text] [Related]

  • 17. The GTPase-activating protein Rap1GAP uses a catalytic asparagine.
    Daumke O, Weyand M, Chakrabarti PP, Vetter IR, Wittinghofer A.
    Nature; 2004 May 13; 429(6988):197-201. PubMed ID: 15141215
    [Abstract] [Full Text] [Related]

  • 18. Allosteric modulation of Ras positions Q61 for a direct role in catalysis.
    Buhrman G, Holzapfel G, Fetics S, Mattos C.
    Proc Natl Acad Sci U S A; 2010 Mar 16; 107(11):4931-6. PubMed ID: 20194776
    [Abstract] [Full Text] [Related]

  • 19. The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
    Scheffzek K, Ahmadian MR, Kabsch W, Wiesmüller L, Lautwein A, Schmitz F, Wittinghofer A.
    Science; 1997 Jul 18; 277(5324):333-8. PubMed ID: 9219684
    [Abstract] [Full Text] [Related]

  • 20. Shift in the equilibrium between on and off states of the allosteric switch in Ras-GppNHp affected by small molecules and bulk solvent composition.
    Holzapfel G, Buhrman G, Mattos C.
    Biochemistry; 2012 Aug 07; 51(31):6114-26. PubMed ID: 22845804
    [Abstract] [Full Text] [Related]

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