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Journal Abstract Search

149 related items for PubMed ID: 24192198

  • 1. The glycogen phosphorylase inhibitor 2-(3-benzylamino-2-oxo-1,2-dihydropyridin-1-yl)-N-(3,4-dichlorobenzyl)acetamide.
    Popova I, Healy PC, Loughlin WA, Karis ND, Jenkins ID.
    Acta Crystallogr C; 2013 Nov; 69(Pt 11):1408-10. PubMed ID: 24192198
    [Abstract] [Full Text] [Related]

  • 2. 2-Oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors: Design, synthesis and structure-activity relationship study.
    Loughlin WA, Jenkins ID, Karis ND, Schweiker SS, Healy PC.
    Eur J Med Chem; 2016 Mar 23; 111():1-14. PubMed ID: 26851835
    [Abstract] [Full Text] [Related]

  • 3. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding.
    Alexacou KM, Hayes JM, Tiraidis C, Zographos SE, Leonidas DD, Chrysina ED, Archontis G, Oikonomakos NG, Paul JV, Varghese B, Loganathan D.
    Proteins; 2008 May 15; 71(3):1307-23. PubMed ID: 18041758
    [Abstract] [Full Text] [Related]

  • 4. Glycogen phosphorylase inhibitory effects of 2-oxo-1,2-dihydropyridin-3-yl amide derivatives.
    Karis ND, Loughlin WA, Jenkins ID, Healy PC.
    Bioorg Med Chem; 2009 Jul 01; 17(13):4724-33. PubMed ID: 19443226
    [Abstract] [Full Text] [Related]

  • 5. Advances in glycogen phosphorylase inhibitor design.
    Oikonomakos NG, Somsák L.
    Curr Opin Investig Drugs; 2008 Apr 01; 9(4):379-95. PubMed ID: 18393105
    [Abstract] [Full Text] [Related]

  • 6. Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: comparison of chrysin and flavopiridol.
    Tsitsanou KE, Hayes JM, Keramioti M, Mamais M, Oikonomakos NG, Kato A, Leonidas DD, Zographos SE.
    Food Chem Toxicol; 2013 Nov 01; 61():14-27. PubMed ID: 23279842
    [Abstract] [Full Text] [Related]

  • 7. Discovery of new nanomolar inhibitors of GPa: Extension of 2-oxo-1,2-dihydropyridinyl-3-yl amide-based GPa inhibitors.
    Loughlin WA, Jenkins ID, Karis ND, Healy PC.
    Eur J Med Chem; 2017 Feb 15; 127():341-356. PubMed ID: 28076824
    [Abstract] [Full Text] [Related]

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  • 10. A New Potent Inhibitor of Glycogen Phosphorylase Reveals the Basicity of the Catalytic Site.
    Mamais M, Degli Esposti A, Kouloumoundra V, Gustavsson T, Monti F, Venturini A, Chrysina ED, Markovitsi D, Gimisis T.
    Chemistry; 2017 Jul 03; 23(37):8800-8805. PubMed ID: 28493496
    [Abstract] [Full Text] [Related]

  • 11. N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.
    Nagy V, Felföldi N, Kónya B, Praly JP, Docsa T, Gergely P, Chrysina ED, Tiraidis C, Kosmopoulou MN, Alexacou KM, Konstantakaki M, Leonidas DD, Zographos SE, Oikonomakos NG, Kozmon S, Tvaroška I, Somsák L.
    Bioorg Med Chem; 2012 Mar 01; 20(5):1801-16. PubMed ID: 22325154
    [Abstract] [Full Text] [Related]

  • 12. High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-β-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors.
    Fischer T, Koulas SM, Tsagkarakou AS, Kyriakis E, Stravodimos GA, Skamnaki VT, Liggri PGV, Zographos SE, Riedl R, Leonidas DD.
    Molecules; 2019 Apr 03; 24(7):. PubMed ID: 30987252
    [Abstract] [Full Text] [Related]

  • 13. Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.
    Chen L, Li H, Liu J, Zhang L, Liu H, Jiang H.
    Bioorg Med Chem; 2007 Nov 01; 15(21):6763-74. PubMed ID: 17719791
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of oleanolic acid dimers as inhibitors of glycogen phosphorylase.
    Cheng K, Liu J, Sun H, Xie J.
    Chem Biodivers; 2010 Mar 01; 7(3):690-7. PubMed ID: 20232331
    [Abstract] [Full Text] [Related]

  • 15. Supramolecular structures in three thiouracil derivatives: 5,6-trimethylene-2-sulfanylidene-1,2-dihydropyrimidin-4(3H)-one, 2-(4-fluorobenzylsulfanyl)-5,6-trimethylenepyrimidin-4(3H)-one and methyl 2-{[2-(4-fluorobenzylsulfanyl)-5,6-trimethylenepyrimidin-4-yl]oxy}acetate.
    Zhou YJ, Lv J, Yu K, Ma JP, Guo DS.
    Acta Crystallogr C Struct Chem; 2014 Apr 01; 70(Pt 4):416-20. PubMed ID: 24705060
    [Abstract] [Full Text] [Related]

  • 16. Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
    Oikonomakos NG, Tiraidis C, Leonidas DD, Zographos SE, Kristiansen M, Jessen CU, Nørskov-Lauritsen L, Agius L.
    J Med Chem; 2006 Sep 21; 49(19):5687-701. PubMed ID: 16970395
    [Abstract] [Full Text] [Related]

  • 17. Crystallographic studies on N-azidoacetyl-beta-D-glucopyranosylamine, an inhibitor of glycogen phosphorylase: comparison with N-acetyl-beta-D-glucopyranosylamine.
    Petsalakis EI, Chrysina ED, Tiraidis C, Hadjiloi T, Leonidas DD, Oikonomakos NG, Aich U, Varghese B, Loganathan D.
    Bioorg Med Chem; 2006 Aug 01; 14(15):5316-24. PubMed ID: 16616506
    [Abstract] [Full Text] [Related]

  • 18. 3-Cyano-6-hydroxy-4-methyl-2-pyridone: two new pseudopolymorphs and two cocrystals with products of an in situ nucleophilic aromatic substitution.
    Gerhardt V, Bolte M.
    Acta Crystallogr C Struct Chem; 2015 Jan 01; 71(Pt 1):19-25. PubMed ID: 25567570
    [Abstract] [Full Text] [Related]

  • 19. Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
    Kantsadi AL, Bokor É, Kun S, Stravodimos GA, Chatzileontiadou DSM, Leonidas DD, Juhász-Tóth É, Szakács A, Batta G, Docsa T, Gergely P, Somsák L.
    Eur J Med Chem; 2016 Nov 10; 123():737-745. PubMed ID: 27522507
    [Abstract] [Full Text] [Related]

  • 20. Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
    Watson KA, Chrysina ED, Tsitsanou KE, Zographos SE, Archontis G, Fleet GW, Oikonomakos NG.
    Proteins; 2005 Dec 01; 61(4):966-83. PubMed ID: 16222658
    [Abstract] [Full Text] [Related]

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