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184 related items for PubMed ID: 24195616

  • 1. Phenethyl isothiocyanate inhibits proliferation and induces apoptosis in pancreatic cancer cells in vitro and in a MIAPaca2 xenograft animal model.
    Stan SD, Singh SV, Whitcomb DC, Brand RE.
    Nutr Cancer; 2014; 66(4):747-55. PubMed ID: 24195616
    [Abstract] [Full Text] [Related]

  • 2. Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax.
    Xiao D, Zeng Y, Choi S, Lew KL, Nelson JB, Singh SV.
    Clin Cancer Res; 2005 Apr 01; 11(7):2670-9. PubMed ID: 15814648
    [Abstract] [Full Text] [Related]

  • 3. Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
    Xiao D, Johnson CS, Trump DL, Singh SV.
    Mol Cancer Ther; 2004 May 01; 3(5):567-75. PubMed ID: 15141014
    [Abstract] [Full Text] [Related]

  • 4. p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition.
    Aggarwal M, Saxena R, Asif N, Sinclair E, Tan J, Cruz I, Berry D, Kallakury B, Pham Q, Wang TTY, Chung FL.
    J Exp Clin Cancer Res; 2019 Jul 15; 38(1):307. PubMed ID: 31307507
    [Abstract] [Full Text] [Related]

  • 5. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
    Wu CL, Huang AC, Yang JS, Liao CL, Lu HF, Chou ST, Ma CY, Hsia TC, Ko YC, Chung JG.
    J Orthop Res; 2011 Aug 15; 29(8):1199-209. PubMed ID: 21374707
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  • 8. Cancer-preventive effect of phenethyl isothiocyanate through tumor microenvironment regulation in a colorectal cancer stem cell xenograft model.
    Shin JM, Lim E, Cho YS, Nho CW.
    Phytomedicine; 2021 Apr 15; 84():153493. PubMed ID: 33626429
    [Abstract] [Full Text] [Related]

  • 9. Phenethyl isothiocyanate (PEITC) inhibits growth of ovarian cancer cells by inducing apoptosis: role of caspase and MAPK activation.
    Satyan KS, Swamy N, Dizon DS, Singh R, Granai CO, Brard L.
    Gynecol Oncol; 2006 Oct 15; 103(1):261-70. PubMed ID: 16624391
    [Abstract] [Full Text] [Related]

  • 10. Bim contributes to phenethyl isothiocyanate-induced apoptosis in breast cancer cells.
    Hahm ER, Singh SV.
    Mol Carcinog; 2012 Jun 15; 51(6):465-74. PubMed ID: 21739479
    [Abstract] [Full Text] [Related]

  • 11. Antitumor activity of phenethyl isothiocyanate in HER2-positive breast cancer models.
    Gupta P, Srivastava SK.
    BMC Med; 2012 Jul 24; 10():80. PubMed ID: 22824293
    [Abstract] [Full Text] [Related]

  • 12. Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth.
    Aggarwal M, Saxena R, Sinclair E, Fu Y, Jacobs A, Dyba M, Wang X, Cruz I, Berry D, Kallakury B, Mueller SC, Agostino SD, Blandino G, Avantaggiati ML, Chung FL.
    Cell Death Differ; 2016 Oct 24; 23(10):1615-27. PubMed ID: 27258787
    [Abstract] [Full Text] [Related]

  • 13. Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells.
    Srivastava SK, Singh SV.
    Carcinogenesis; 2004 Sep 24; 25(9):1701-9. PubMed ID: 15117814
    [Abstract] [Full Text] [Related]

  • 14. Phenethyl isothiocyanate triggers apoptosis in human malignant melanoma A375.S2 cells through reactive oxygen species and the mitochondria-dependent pathways.
    Huang SH, Hsu MH, Hsu SC, Yang JS, Huang WW, Huang AC, Hsiao YP, Yu CC, Chung JG.
    Hum Exp Toxicol; 2014 Mar 24; 33(3):270-83. PubMed ID: 23760257
    [Abstract] [Full Text] [Related]

  • 15. Phenethyl isothiocyanate induces apoptosis and inhibits cell proliferation and invasion in Hep-2 laryngeal cancer cells.
    Dai MY, Wang Y, Chen C, Li F, Xiao BK, Chen SM, Tao ZZ.
    Oncol Rep; 2016 May 24; 35(5):2657-64. PubMed ID: 26986926
    [Abstract] [Full Text] [Related]

  • 16. Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest.
    Chiao JW, Wu H, Ramaswamy G, Conaway CC, Chung FL, Wang L, Liu D.
    Carcinogenesis; 2004 Aug 24; 25(8):1403-8. PubMed ID: 15016658
    [Abstract] [Full Text] [Related]

  • 17. Phenethyl isothiocyanate (PEITC) promotes G2/M phase arrest via p53 expression and induces apoptosis through caspase- and mitochondria-dependent signaling pathways in human prostate cancer DU 145 cells.
    Tang NY, Huang YT, Yu CS, Ko YC, Wu SH, Ji BC, Yang JS, Yang JL, Hsia TC, Chen YY, Chung JG.
    Anticancer Res; 2011 May 24; 31(5):1691-702. PubMed ID: 21617228
    [Abstract] [Full Text] [Related]

  • 18. Combined treatment with cotylenin A and phenethyl isothiocyanate induces strong antitumor activity mainly through the induction of ferroptotic cell death in human pancreatic cancer cells.
    Kasukabe T, Honma Y, Okabe-Kado J, Higuchi Y, Kato N, Kumakura S.
    Oncol Rep; 2016 Aug 24; 36(2):968-76. PubMed ID: 27375275
    [Abstract] [Full Text] [Related]

  • 19. Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells.
    Bommareddy A, Hahm ER, Xiao D, Powolny AA, Fisher AL, Jiang Y, Singh SV.
    Cancer Res; 2009 Apr 15; 69(8):3704-12. PubMed ID: 19336571
    [Abstract] [Full Text] [Related]

  • 20. Epigenetic reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells.
    Boyanapalli SS, Li W, Fuentes F, Guo Y, Ramirez CN, Gonzalez XP, Pung D, Kong AN.
    Pharmacol Res; 2016 Dec 15; 114():175-184. PubMed ID: 27818231
    [Abstract] [Full Text] [Related]

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