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630 related items for PubMed ID: 2421728

  • 1. Effects of several newer cardiotonic drugs on cardiac cyclic AMP metabolism.
    Ahn HS, Eardley D, Watkins R, Prioli N.
    Biochem Pharmacol; 1986 Apr 01; 35(7):1113-21. PubMed ID: 2421728
    [Abstract] [Full Text] [Related]

  • 2. Proteolysis of cyclic AMP phosphodiesterase-II attenuates its ability to be inhibited by compounds which exert positive inotropic actions in cardiac tissue.
    Price B, Pyne NJ, Houslay MD.
    Biochem Pharmacol; 1987 Dec 01; 36(23):4047-54. PubMed ID: 2825712
    [Abstract] [Full Text] [Related]

  • 3. Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle.
    Endoh M, Yanagisawa T, Taira N, Blinks JR.
    Circulation; 1986 Mar 01; 73(3 Pt 2):III117-33. PubMed ID: 2417745
    [Abstract] [Full Text] [Related]

  • 4. Differential inhibition of cardiac cyclic nucleotide phosphodiesterase isozymes by cardiotonic drugs.
    Harrison SA, Chang ML, Beavo JA.
    Circulation; 1986 Mar 01; 73(3 Pt 2):III109-16. PubMed ID: 3002661
    [Abstract] [Full Text] [Related]

  • 5. Implication of cyclic AMP in the positive inotropic effects of cyclic GMP-inhibited cyclic AMP phosphodiesterase inhibitors on guinea pig isolated left atria.
    Muller B, Lugnier C, Stoclet JC.
    J Cardiovasc Pharmacol; 1990 Mar 01; 15(3):444-51. PubMed ID: 1691369
    [Abstract] [Full Text] [Related]

  • 6. Comparison of cyclic nucleotide phosphodiesterase isoenzymes in rat and rabbit ventricular myocardium: positive inotropic and phosphodiesterase inhibitory effects of Org 30029, milrinone and rolipram.
    Shahid M, Nicholson CD.
    Naunyn Schmiedebergs Arch Pharmacol; 1990 Dec 01; 342(6):698-705. PubMed ID: 1710786
    [Abstract] [Full Text] [Related]

  • 7. Effects of a cardiotonic quinolinone derivative Y-20487 on the isoproterenol-induced positive inotropic action and cyclic AMP accumulation in rat ventricular myocardium: comparison with rolipram, Ro 20-1724, milrinone, and isobutylmethylxanthine.
    Katano Y, Endoh M.
    J Cardiovasc Pharmacol; 1992 Dec 01; 20(5):715-22. PubMed ID: 1280732
    [Abstract] [Full Text] [Related]

  • 8. Relationship between inhibition of cardiac muscle phosphodiesterases, changes in cyclic nucleotide levels, and contractile response for CI-914 and other novel cardiotonics.
    Weishaar RE, Quade MM, Schenden JA, Evans DB.
    J Cyclic Nucleotide Protein Phosphor Res; 1985 Dec 01; 10(6):551-64. PubMed ID: 3003170
    [Abstract] [Full Text] [Related]

  • 9. Isolation and characterization of bovine cardiac muscle cGMP-inhibited phosphodiesterase: a receptor for new cardiotonic drugs.
    Harrison SA, Reifsnyder DH, Gallis B, Cadd GG, Beavo JA.
    Mol Pharmacol; 1986 May 01; 29(5):506-14. PubMed ID: 3010079
    [Abstract] [Full Text] [Related]

  • 10. Mechanism of action and cardiotonic activity of a new phosphodiesterase inhibitor, the benzimidazole derivative adibendan (BM 14.478), in guinea-pig hearts.
    Bethke T, Brunkhorst D, von der Leyen H, Meyer W, Nigbur R, Scholz H.
    Naunyn Schmiedebergs Arch Pharmacol; 1988 May 01; 337(5):576-82. PubMed ID: 2457816
    [Abstract] [Full Text] [Related]

  • 11. Multiple molecular forms of cyclic nucleotide phosphodiesterase in cardiac and smooth muscle and in platelets. Isolation, characterization, and effects of various reference phosphodiesterase inhibitors and cardiotonic agents.
    Weishaar RE, Burrows SD, Kobylarz DC, Quade MM, Evans DB.
    Biochem Pharmacol; 1986 Mar 01; 35(5):787-800. PubMed ID: 3006691
    [Abstract] [Full Text] [Related]

  • 12. Mechanism underlying the reduced positive inotropic effects of the phosphodiesterase III inhibitors pimobendan, adibendan and saterinone in failing as compared to nonfailing human cardiac muscle preparations.
    von der Leyen H, Mende U, Meyer W, Neumann J, Nose M, Schmitz W, Scholz H, Starbatty J, Stein B, Wenzlaff H.
    Naunyn Schmiedebergs Arch Pharmacol; 1991 Jul 01; 344(1):90-100. PubMed ID: 1723153
    [Abstract] [Full Text] [Related]

  • 13. Selective inhibition of cAMP phosphodiesterase III activity by the cardiotonic agent saterinone in guinea pig myocardium.
    Brunkhorst D, von der Leyen H, Meyer W, Schmidt-Schumacher C, Scholz H.
    Arzneimittelforschung; 1988 Sep 01; 38(9):1293-8. PubMed ID: 2852013
    [Abstract] [Full Text] [Related]

  • 14. Positive inotropic activity of 5-amino-6-cyano-1,3-dimethyl-1,2,3,4-tetrahydropyrido[2,3-d]pyrim idine-2,4-dione in cardiac muscle from guinea-pig and man. Part 6: Compounds with positive inotropic activity.
    Heber D, Heers C, Ravens U.
    Pharmazie; 1993 Jul 01; 48(7):537-41. PubMed ID: 7692456
    [Abstract] [Full Text] [Related]

  • 15. Phosphodiesterase isozyme inhibition, activation of the cAMP system, and positive inotropy mediated by milrinone in isolated guinea pig cardiac muscle.
    Silver PJ, Harris AL, Canniff PC, Lepore RE, Bentley RG, Hamel LT, Evans DB.
    J Cardiovasc Pharmacol; 1989 Apr 01; 13(4):530-40. PubMed ID: 2470989
    [Abstract] [Full Text] [Related]

  • 16. Phosphodiesterase inhibition in ventricular cardiomyocytes from guinea-pig hearts.
    Bethke T, Meyer W, Schmitz W, Scholz H, Stein B, Thomas K, Wenzlaff H.
    Br J Pharmacol; 1992 Sep 01; 107(1):127-33. PubMed ID: 1384905
    [Abstract] [Full Text] [Related]

  • 17. Relation of positive inotropic and chronotropic effects of pimobendan, UD-CG 212 Cl, milrinone and other phosphodiesterase inhibitors to phosphodiesterase III inhibition in guinea-pig heart.
    Brunkhorst D, v der Leyen H, Meyer W, Nigbur R, Schmidt-Schumacher C, Scholz H.
    Naunyn Schmiedebergs Arch Pharmacol; 1989 May 01; 339(5):575-83. PubMed ID: 2549430
    [Abstract] [Full Text] [Related]

  • 18. Phosphodiesterase-inhibiting properties of newer inotropic agents.
    Scholz H, Meyer W.
    Circulation; 1986 Mar 01; 73(3 Pt 2):III99-108. PubMed ID: 2417748
    [Abstract] [Full Text] [Related]

  • 19. Differential effects of phosphodiesterase inhibitors on accumulation of cyclic AMP in isolated ventricular cardiomyocytes.
    Kelso EJ, McDermott BJ, Silke B.
    Biochem Pharmacol; 1995 Feb 14; 49(4):441-52. PubMed ID: 7872950
    [Abstract] [Full Text] [Related]

  • 20. Pharmacology of the bipyridines: amrinone and milrinone.
    Alousi AA, Johnson DC.
    Circulation; 1986 Mar 14; 73(3 Pt 2):III10-24. PubMed ID: 2417744
    [Abstract] [Full Text] [Related]

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