These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

222 related items for PubMed ID: 2421872

  • 1. Hydrolytic cleavage of methotrexate gamma-polyglutamates by folylpolyglutamyl hydrolase derived from various tumors and normal tissues of the mouse.
    Samuels LL, Goutas LJ, Priest DG, Piper JR, Sirotnak FM.
    Cancer Res; 1986 May; 46(5):2230-5. PubMed ID: 2421872
    [Abstract] [Full Text] [Related]

  • 2. Differing specificities for 4-aminofolate analogues of folylpolyglutamyl synthetase from tumors and proliferative intestinal epithelium of the mouse with significance for selective antitumor action.
    Rumberger BG, Barrueco JR, Sirotnak FM.
    Cancer Res; 1990 Aug 01; 50(15):4639-43. PubMed ID: 2369741
    [Abstract] [Full Text] [Related]

  • 3. Differential synthesis of methotrexate polyglutamates in normal proliferative and neoplastic mouse tissues in vivo.
    Poser RG, Sirotnak FM, Chello PL.
    Cancer Res; 1981 Nov 01; 41(11 Pt 1):4441-6. PubMed ID: 6171339
    [Abstract] [Full Text] [Related]

  • 4. Studies on the in vivo synthesis of methotrexate polyglutamates and their efflux properties in normal, proliferative, and neoplastic mouse tissues.
    Poser RG, Sirotnak FM.
    Adv Exp Med Biol; 1983 Nov 01; 163():259-74. PubMed ID: 6193689
    [Abstract] [Full Text] [Related]

  • 5. Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells.
    Whitehead VM.
    Cancer Res; 1977 Feb 01; 37(2):408-12. PubMed ID: 832265
    [Abstract] [Full Text] [Related]

  • 6. Proliferation-dependent cytotoxicity of methotrexate in murine L5178Y leukemia.
    Fernandes DJ, Sur P, Kute TE, Capizzi RL.
    Cancer Res; 1988 Oct 15; 48(20):5638-44. PubMed ID: 2458828
    [Abstract] [Full Text] [Related]

  • 7. Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.
    Samuels LL, Moccio DM, Sirotnak FM.
    Cancer Res; 1985 Apr 15; 45(4):1488-95. PubMed ID: 3978616
    [Abstract] [Full Text] [Related]

  • 8. Secretion of gamma-glutamyl hydrolase in vitro.
    O'Connor BM, Rotundo RF, Nimec Z, McGuire JJ, Galivan J.
    Cancer Res; 1991 Aug 01; 51(15):3874-81. PubMed ID: 1713122
    [Abstract] [Full Text] [Related]

  • 9. Role of folylpolyglutamate synthetase in the regulation of methotrexate polyglutamate formation in H35 hepatoma cells.
    Johnson TB, Nair MG, Galivan J.
    Cancer Res; 1988 May 01; 48(9):2426-31. PubMed ID: 2451560
    [Abstract] [Full Text] [Related]

  • 10. Methotrexate intracellular disposition in acute lymphoblastic leukemia: a mathematical model of gamma-glutamyl hydrolase activity.
    Panetta JC, Wall A, Pui CH, Relling MV, Evans WE.
    Clin Cancer Res; 2002 Jul 01; 8(7):2423-9. PubMed ID: 12114448
    [Abstract] [Full Text] [Related]

  • 11. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells.
    Matherly LH, Barlowe CK, Goldman ID.
    Cancer Res; 1986 Feb 01; 46(2):588-93. PubMed ID: 2416428
    [Abstract] [Full Text] [Related]

  • 12. Formation of methotrexate polyglutamates in purified myeloid precursor cells from normal human bone marrow.
    Koizumi S, Curt GA, Fine RL, Griffin JD, Chabner BA.
    J Clin Invest; 1985 Mar 01; 75(3):1008-14. PubMed ID: 2579975
    [Abstract] [Full Text] [Related]

  • 13. Metabolic turnover of methotrexate polyglutamates in lysosomes derived from S180 cells. Definition of a two-step process limited by mediated lysosomal permeation of polyglutamates and activating reduced sulfhydryl compounds.
    Barrueco JR, O'Leary DF, Sirotnak FM.
    J Biol Chem; 1992 Aug 05; 267(22):15356-61. PubMed ID: 1379226
    [Abstract] [Full Text] [Related]

  • 14. [Separation of methotrexate-polyglutamates by capillary electrophoresis and its application to the measurement of gamma-glutamyl hydrolase activity in human leukemia cells in culture].
    Takemura Y, Kobayashi H, Sekiguchi S.
    Rinsho Byori; 1996 Jan 05; 44(1):51-6. PubMed ID: 8691640
    [Abstract] [Full Text] [Related]

  • 15. gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
    Longo GS, Gorlick R, Tong WP, Lin S, Steinherz P, Bertino JR.
    Oncol Res; 1997 Jan 05; 9(5):259-63. PubMed ID: 9306433
    [Abstract] [Full Text] [Related]

  • 16. Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
    Jolivet J, Chabner BA.
    J Clin Invest; 1983 Sep 05; 72(3):773-8. PubMed ID: 6193143
    [Abstract] [Full Text] [Related]

  • 17. Proposed mechanism of therapeutic selectivity for 9-beta-D-arabinofuranosyl-2-fluoroadenine against murine leukemia based upon lower capacities for transport and phosphorylation in proliferative intestinal epithelium compared to tumor cells.
    Barrueco JR, Jacobsen DM, Chang CH, Brockman RW, Sirotnak FM.
    Cancer Res; 1987 Feb 01; 47(3):700-6. PubMed ID: 3802076
    [Abstract] [Full Text] [Related]

  • 18. Role of polyglutamates in methotrexate action.
    Wilmanns W, Schalhorn A.
    Chemioterapia; 1985 Oct 01; 4(5):349-53. PubMed ID: 2416481
    [Abstract] [Full Text] [Related]

  • 19. Enhanced polyglutamylation of aminopterin relative to methotrexate in the Ehrlich ascites tumor cell in vitro.
    Matherly LH, Voss MK, Anderson LA, Fry DW, Goldman ID.
    Cancer Res; 1985 Mar 01; 45(3):1073-8. PubMed ID: 2578870
    [Abstract] [Full Text] [Related]

  • 20. Characterization of human cellular gamma-glutamyl hydrolase.
    Rhee MS, Lindau-Shepard B, Chave KJ, Galivan J, Ryan TJ.
    Mol Pharmacol; 1998 Jun 01; 53(6):1040-6. PubMed ID: 9614206
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 12.