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672 related items for PubMed ID: 24222351

  • 1. Resident macrophages mediate islet amyloid polypeptide-induced islet IL-1β production and β-cell dysfunction.
    Westwell-Roper CY, Ehses JA, Verchere CB.
    Diabetes; 2014 May; 63(5):1698-711. PubMed ID: 24222351
    [Abstract] [Full Text] [Related]

  • 2. IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.
    Westwell-Roper C, Dai DL, Soukhatcheva G, Potter KJ, van Rooijen N, Ehses JA, Verchere CB.
    J Immunol; 2011 Sep 01; 187(5):2755-65. PubMed ID: 21813778
    [Abstract] [Full Text] [Related]

  • 3. Dual role of interleukin-1β in islet amyloid formation and its β-cell toxicity: Implications for type 2 diabetes and islet transplantation.
    Park YJ, Warnock GL, Ao Z, Safikhan N, Meloche M, Asadi A, Kieffer TJ, Marzban L.
    Diabetes Obes Metab; 2017 May 01; 19(5):682-694. PubMed ID: 28058779
    [Abstract] [Full Text] [Related]

  • 4. Alpha1-antitrypsin ameliorates islet amyloid-induced glucose intolerance and β-cell dysfunction.
    Rodríguez-Comas J, Moreno-Vedia J, Obach M, Castaño C, de Pablo S, Alcarraz-Vizán G, Díaz-Catalán D, Mestre A, Horrillo R, Costa M, Novials A, Servitja JM.
    Mol Metab; 2020 Jul 01; 37():100984. PubMed ID: 32229246
    [Abstract] [Full Text] [Related]

  • 5. Differential Activation of Innate Immune Pathways by Distinct Islet Amyloid Polypeptide (IAPP) Aggregates.
    Westwell-Roper C, Denroche HC, Ehses JA, Verchere CB.
    J Biol Chem; 2016 Apr 22; 291(17):8908-17. PubMed ID: 26786104
    [Abstract] [Full Text] [Related]

  • 6. IL-1 mediates amyloid-associated islet dysfunction and inflammation in human islet amyloid polypeptide transgenic mice.
    Westwell-Roper CY, Chehroudi CA, Denroche HC, Courtade JA, Ehses JA, Verchere CB.
    Diabetologia; 2015 Mar 22; 58(3):575-85. PubMed ID: 25491100
    [Abstract] [Full Text] [Related]

  • 7. The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation.
    Kulak K, Westermark GT, Papac-Milicevic N, Renström E, Blom AM, King BC.
    Diabetologia; 2017 Aug 22; 60(8):1522-1533. PubMed ID: 28500395
    [Abstract] [Full Text] [Related]

  • 8. Intra- and extracellular amyloid fibrils are formed in cultured pancreatic islets of transgenic mice expressing human islet amyloid polypeptide.
    de Koning EJ, Morris ER, Hofhuis FM, Posthuma G, Höppener JW, Morris JF, Capel PJ, Clark A, Verbeek JS.
    Proc Natl Acad Sci U S A; 1994 Aug 30; 91(18):8467-71. PubMed ID: 8078905
    [Abstract] [Full Text] [Related]

  • 9. PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice.
    Chen YC, Mains RE, Eipper BA, Hoffman BG, Czyzyk TA, Pintar JE, Verchere CB.
    Diabetologia; 2020 Mar 30; 63(3):561-576. PubMed ID: 31984442
    [Abstract] [Full Text] [Related]

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  • 11. Human islet amyloid polypeptide accumulates at similar sites in islets of transgenic mice and humans.
    de Koning EJ, Höppener JW, Verbeek JS, Oosterwijk C, van Hulst KL, Baker CA, Lips CJ, Morris JF, Clark A.
    Diabetes; 1994 May 30; 43(5):640-4. PubMed ID: 8168639
    [Abstract] [Full Text] [Related]

  • 12. Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice.
    Castillo JJ, Aplin AC, Hackney DJ, Hogan MF, Esser N, Templin AT, Akter R, Kahn SE, Raleigh DP, Zraika S, Hull RL.
    Diabetologia; 2022 Oct 30; 65(10):1687-1700. PubMed ID: 35871651
    [Abstract] [Full Text] [Related]

  • 13. Amyloid formation disrupts the balance between interleukin-1β and interleukin-1 receptor antagonist in human islets.
    Hui Q, Asadi A, Park YJ, Kieffer TJ, Ao Z, Warnock GL, Marzban L.
    Mol Metab; 2017 Aug 30; 6(8):833-844. PubMed ID: 28752047
    [Abstract] [Full Text] [Related]

  • 14. Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro.
    Templin AT, Mellati M, Meier DT, Esser N, Hogan MF, Castillo JJ, Akter R, Raleigh DP, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2020 Nov 30; 63(11):2385-2395. PubMed ID: 32728889
    [Abstract] [Full Text] [Related]

  • 15. Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model.
    Höppener JW, Oosterwijk C, Nieuwenhuis MG, Posthuma G, Thijssen JH, Vroom TM, Ahrén B, Lips CJ.
    Diabetologia; 1999 Apr 30; 42(4):427-34. PubMed ID: 10230646
    [Abstract] [Full Text] [Related]

  • 16. Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice.
    Lin CY, Gurlo T, Kayed R, Butler AE, Haataja L, Glabe CG, Butler PC.
    Diabetes; 2007 May 30; 56(5):1324-32. PubMed ID: 17353506
    [Abstract] [Full Text] [Related]

  • 17. Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo.
    Mo XD, Gao LP, Wang QJ, Yin J, Jing YH.
    Lipids Health Dis; 2018 Mar 09; 17(1):42. PubMed ID: 29523142
    [Abstract] [Full Text] [Related]

  • 18. Macrophages, cytokines and beta-cell death in Type 2 diabetes.
    Ehses JA, Böni-Schnetzler M, Faulenbach M, Donath MY.
    Biochem Soc Trans; 2008 Jun 09; 36(Pt 3):340-2. PubMed ID: 18481953
    [Abstract] [Full Text] [Related]

  • 19. The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity.
    Esser N, Hogan MF, Templin AT, Akter R, Fountaine BS, Castillo JJ, El-Osta A, Manathunga L, Zhyvoloup A, Raleigh DP, Zraika S, Hull RL, Kahn SE.
    Diabetologia; 2024 Sep 09; 67(9):1897-1911. PubMed ID: 39245780
    [Abstract] [Full Text] [Related]

  • 20. Human IAPP amyloidogenic properties and pancreatic β-cell death.
    Fernández MS.
    Cell Calcium; 2014 Nov 09; 56(5):416-27. PubMed ID: 25224501
    [Abstract] [Full Text] [Related]

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