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Journal Abstract Search

153 related items for PubMed ID: 24225203

  • 1. Mitochondrial targeting of α-tocopheryl succinate enhances its anti-mesothelioma efficacy.
    Kovarova J, Bajzikova M, Vondrusova M, Stursa J, Goodwin J, Nguyen M, Zobalova R, Pesdar EA, Truksa J, Tomasetti M, Dong LF, Neuzil J.
    Redox Rep; 2014 Jan; 19(1):16-25. PubMed ID: 24225203
    [Abstract] [Full Text] [Related]

  • 2. Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II.
    Dong LF, Jameson VJ, Tilly D, Cerny J, Mahdavian E, Marín-Hernández A, Hernández-Esquivel L, Rodríguez-Enríquez S, Stursa J, Witting PK, Stantic B, Rohlena J, Truksa J, Kluckova K, Dyason JC, Ledvina M, Salvatore BA, Moreno-Sánchez R, Coster MJ, Ralph SJ, Smith RA, Neuzil J.
    J Biol Chem; 2011 Feb 04; 286(5):3717-28. PubMed ID: 21059645
    [Abstract] [Full Text] [Related]

  • 3. Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing.
    Rohlena J, Dong LF, Kluckova K, Zobalova R, Goodwin J, Tilly D, Stursa J, Pecinova A, Philimonenko A, Hozak P, Banerjee J, Ledvina M, Sen CK, Houstek J, Coster MJ, Neuzil J.
    Antioxid Redox Signal; 2011 Dec 15; 15(12):2923-35. PubMed ID: 21902599
    [Abstract] [Full Text] [Related]

  • 4. Mitochondrially targeted vitamin E succinate modulates expression of mitochondrial DNA transcripts and mitochondrial biogenesis.
    Truksa J, Dong LF, Rohlena J, Stursa J, Vondrusova M, Goodwin J, Nguyen M, Kluckova K, Rychtarcikova Z, Lettlova S, Spacilova J, Stapelberg M, Zoratti M, Neuzil J.
    Antioxid Redox Signal; 2015 Apr 10; 22(11):883-900. PubMed ID: 25578105
    [Abstract] [Full Text] [Related]

  • 5. (+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo.
    dos Santos GA, Abreu e Lima RS, Pestana CR, Lima AS, Scheucher PS, Thomé CH, Gimenes-Teixeira HL, Santana-Lemos BA, Lucena-Araujo AR, Rodrigues FP, Nasr R, Uyemura SA, Falcão RP, de Thé H, Pandolfi PP, Curti C, Rego EM.
    Leukemia; 2012 Mar 10; 26(3):451-60. PubMed ID: 21869839
    [Abstract] [Full Text] [Related]

  • 6. Molecular mechanism for the selective impairment of cancer mitochondrial function by a mitochondrially targeted vitamin E analogue.
    Rodríguez-Enríquez S, Hernández-Esquivel L, Marín-Hernández A, Dong LF, Akporiaye ET, Neuzil J, Ralph SJ, Moreno-Sánchez R.
    Biochim Biophys Acta; 2012 Sep 10; 1817(9):1597-607. PubMed ID: 22627082
    [Abstract] [Full Text] [Related]

  • 7. Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II.
    Dong LF, Freeman R, Liu J, Zobalova R, Marin-Hernandez A, Stantic M, Rohlena J, Valis K, Rodriguez-Enriquez S, Butcher B, Goodwin J, Brunk UT, Witting PK, Moreno-Sanchez R, Scheffler IE, Ralph SJ, Neuzil J.
    Clin Cancer Res; 2009 Mar 01; 15(5):1593-600. PubMed ID: 19223492
    [Abstract] [Full Text] [Related]

  • 8. Tocopheramine succinate and tocopheryl succinate: mechanism of mitochondrial inhibition and superoxide radical production.
    Gruber J, Staniek K, Krewenka C, Moldzio R, Patel A, Böhmdorfer S, Rosenau T, Gille L.
    Bioorg Med Chem; 2014 Jan 15; 22(2):684-91. PubMed ID: 24393721
    [Abstract] [Full Text] [Related]

  • 9. Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner.
    Yan B, Stantic M, Zobalova R, Bezawork-Geleta A, Stapelberg M, Stursa J, Prokopova K, Dong L, Neuzil J.
    BMC Cancer; 2015 May 13; 15():401. PubMed ID: 25967547
    [Abstract] [Full Text] [Related]

  • 10. Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy.
    Dong LF, Jameson VJ, Tilly D, Prochazka L, Rohlena J, Valis K, Truksa J, Zobalova R, Mahdavian E, Kluckova K, Stantic M, Stursa J, Freeman R, Witting PK, Norberg E, Goodwin J, Salvatore BA, Novotna J, Turanek J, Ledvina M, Hozak P, Zhivotovsky B, Coster MJ, Ralph SJ, Smith RA, Neuzil J.
    Free Radic Biol Med; 2011 Jun 01; 50(11):1546-55. PubMed ID: 21402148
    [Abstract] [Full Text] [Related]

  • 11. Mitochondrial targeting overcomes ABCA1-dependent resistance of lung carcinoma to α-tocopheryl succinate.
    Prochazka L, Koudelka S, Dong LF, Stursa J, Goodwin J, Neca J, Slavik J, Ciganek M, Masek J, Kluckova K, Nguyen M, Turanek J, Neuzil J.
    Apoptosis; 2013 Mar 01; 18(3):286-99. PubMed ID: 23299931
    [Abstract] [Full Text] [Related]

  • 12. Alpha-tocopheryl succinate inhibits malignant mesothelioma by disrupting the fibroblast growth factor autocrine loop: mechanism and the role of oxidative stress.
    Stapelberg M, Gellert N, Swettenham E, Tomasetti M, Witting PK, Procopio A, Neuzil J.
    J Biol Chem; 2005 Jul 08; 280(27):25369-76. PubMed ID: 15878867
    [Abstract] [Full Text] [Related]

  • 13. VCPA, a novel synthetic derivative of α-tocopheryl succinate, sensitizes human gastric cancer to doxorubicin-induced apoptosis via ROS-dependent mitochondrial dysfunction.
    Wu H, Liu S, Gong J, Liu J, Zhang Q, Leng X, Zhang N, Li Y.
    Cancer Lett; 2017 May 01; 393():22-32. PubMed ID: 28216375
    [Abstract] [Full Text] [Related]

  • 14. Alpha-Tocopheryl succinate: toxicity and lack of anti-tumour activity in immuno-competent mice.
    Ireland DJ, Kissick HT, Beilharz MW.
    Food Chem Toxicol; 2008 Feb 01; 46(2):508-12. PubMed ID: 17923224
    [Abstract] [Full Text] [Related]

  • 15. Indoleamine-2,3-dioxygenase elevated in tumor-initiating cells is suppressed by mitocans.
    Stapelberg M, Zobalova R, Nguyen MN, Walker T, Stantic M, Goodwin J, Pasdar EA, Thai T, Prokopova K, Yan B, Hall S, de Pennington N, Thomas SR, Grant G, Stursa J, Bajzikova M, Meedeniya AC, Truksa J, Ralph SJ, Ansorge O, Dong LF, Neuzil J.
    Free Radic Biol Med; 2014 Feb 01; 67():41-50. PubMed ID: 24145120
    [Abstract] [Full Text] [Related]

  • 16. Co-delivery nanocarriers targeting folate receptor and encapsulating 2-deoxyglucose and α-tocopheryl succinate enhance anti-tumor effect in vivo.
    Lei X, Li K, Liu Y, Wang ZY, Ruan BJ, Wang L, Xiang A, Wu D, Lu Z.
    Int J Nanomedicine; 2017 Feb 01; 12():5701-5715. PubMed ID: 28848348
    [Abstract] [Full Text] [Related]

  • 17. Induction of Mitochondrial Cell Death and Reversal of Anticancer Drug Resistance via Nanocarriers Composed of a Triphenylphosphonium Derivative of Tocopheryl Polyethylene Glycol Succinate.
    Singh Y, Viswanadham KKDR, Pawar VK, Meher J, Jajoriya AK, Omer A, Jaiswal S, Dewangan J, Bora HK, Singh P, Rath SK, Lal J, Mishra DP, Chourasia MK.
    Mol Pharm; 2019 Sep 03; 16(9):3744-3759. PubMed ID: 31441308
    [Abstract] [Full Text] [Related]

  • 18. α-Tocopheryloxyacetic acid is superior to α-tocopheryl succinate in suppressing HER2-high breast carcinomas due to its higher stability.
    Dong LF, Grant G, Massa H, Zobalova R, Akporiaye E, Neuzil J.
    Int J Cancer; 2012 Sep 01; 131(5):1052-8. PubMed ID: 22038845
    [Abstract] [Full Text] [Related]

  • 19. Tocopherol-associated protein-1 accelerates apoptosis induced by alpha-tocopheryl succinate in mesothelioma cells.
    Neuzil J, Dong LF, Wang XF, Zingg JM.
    Biochem Biophys Res Commun; 2006 May 19; 343(4):1113-7. PubMed ID: 16579965
    [Abstract] [Full Text] [Related]

  • 20. Alpha-tocopheryl succinate inhibits autophagic survival of prostate cancer cells induced by vitamin K3 and ascorbate to trigger cell death.
    Tomasetti M, Nocchi L, Neuzil J, Goodwin J, Nguyen M, Dong L, Manzella N, Staffolani S, Milanese C, Garrone B, Alleva R, Borghi B, Santarelli L, Guerrieri R.
    PLoS One; 2012 May 19; 7(12):e52263. PubMed ID: 23272231
    [Abstract] [Full Text] [Related]

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