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154 related items for PubMed ID: 24228690

  • 1. Inhibition of microtubule assembly by a complex of actin and antitumor macrolide aplyronine A.
    Kita M, Hirayama Y, Yoneda K, Yamagishi K, Chinen T, Usui T, Sumiya E, Uesugi M, Kigoshi H.
    J Am Chem Soc; 2013 Dec 04; 135(48):18089-95. PubMed ID: 24228690
    [Abstract] [Full Text] [Related]

  • 2. Development of photoaffinity derivatives of the antitumor macrolide aplyronine A, a PPI-inducer between actin and tubulin.
    Kita M, Yamagishi K, Tsuchiya K, Seguchi Y, Nakane H, Kigoshi H.
    Bioorg Med Chem; 2017 Dec 15; 25(24):6322-6331. PubMed ID: 29042221
    [Abstract] [Full Text] [Related]

  • 3. Marine natural products that interfere with multiple cytoskeletal protein interactions.
    Kita M, Kigoshi H.
    Nat Prod Rep; 2015 Apr 15; 32(4):534-42. PubMed ID: 25512265
    [Abstract] [Full Text] [Related]

  • 4. Analysis of the aplyronine A-induced protein-protein interaction between actin and tubulin by surface plasmon resonance.
    Hirayama Y, Yamagishi K, Suzuki T, Kawagishi H, Kita M, Kigoshi H.
    Bioorg Med Chem; 2016 Jun 15; 24(12):2809-14. PubMed ID: 27161875
    [Abstract] [Full Text] [Related]

  • 5. Interactions of the antitumor macrolide aplyronine A with actin and actin-related proteins established by its versatile photoaffinity derivatives.
    Kita M, Hirayama Y, Yamagishi K, Yoneda K, Fujisawa R, Kigoshi H.
    J Am Chem Soc; 2012 Dec 19; 134(50):20314-7. PubMed ID: 23198778
    [Abstract] [Full Text] [Related]

  • 6. Structure-activity relationship studies on an antitumor marine macrolide using aplyronine a-swinholide A hybrid.
    Ohyoshi T, Takano A, Kikuchi I, Ogura T, Namiki M, Miyazaki Y, Hirano T, Konishi S, Ebihara Y, Takeno K, Hayakawa I, Kigoshi H.
    Org Biomol Chem; 2022 Apr 06; 20(14):2922-2938. PubMed ID: 35322840
    [Abstract] [Full Text] [Related]

  • 7. Structure basis for antitumor effect of aplyronine a.
    Hirata K, Muraoka S, Suenaga K, Kuroda T, Kato K, Tanaka H, Yamamoto M, Takata M, Yamada K, Kigoshi H.
    J Mol Biol; 2006 Mar 03; 356(4):945-54. PubMed ID: 16406066
    [Abstract] [Full Text] [Related]

  • 8. Apoptosis-inducing activity of the actin-depolymerizing agent aplyronine A and its side-chain derivatives.
    Ohno O, Morita M, Kitamura K, Teruya T, Yoneda K, Kita M, Kigoshi H, Suenaga K.
    Bioorg Med Chem Lett; 2013 Mar 01; 23(5):1467-71. PubMed ID: 23357626
    [Abstract] [Full Text] [Related]

  • 9. Development of a novel inducer of protein-protein interactions based on aplyronine A.
    Ohyoshi T, Takano A, Namiki M, Ogura T, Miyazaki Y, Ebihara Y, Takeno K, Hayakawa I, Kigoshi H.
    Chem Commun (Camb); 2018 Aug 21; 54(68):9537-9540. PubMed ID: 30094443
    [Abstract] [Full Text] [Related]

  • 10. Spongistatin 1, a highly cytotoxic, sponge-derived, marine natural product that inhibits mitosis, microtubule assembly, and the binding of vinblastine to tubulin.
    Bai R, Cichacz ZA, Herald CL, Pettit GR, Hamel E.
    Mol Pharmacol; 1993 Oct 21; 44(4):757-66. PubMed ID: 8232226
    [Abstract] [Full Text] [Related]

  • 11. Development of highly cytotoxic and actin-depolymerizing biotin derivatives of aplyronine A.
    Kita M, Hirayama Y, Sugiyama M, Kigoshi H.
    Angew Chem Int Ed Engl; 2011 Oct 10; 50(42):9871-4. PubMed ID: 21954061
    [Abstract] [Full Text] [Related]

  • 12. Toward aplyronine payloads for antibody-drug conjugates: total synthesis of aplyronines A and D.
    AnŽiček N, Williams S, Housden MP, Paterson I.
    Org Biomol Chem; 2018 Feb 21; 16(8):1343-1350. PubMed ID: 29393939
    [Abstract] [Full Text] [Related]

  • 13. Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
    Guzmán EA, Xu Q, Pitts TP, Mitsuhashi KO, Baker C, Linley PA, Oestreicher J, Tendyke K, Winder PL, Suh EM, Wright AE.
    Int J Cancer; 2016 Nov 01; 139(9):2116-26. PubMed ID: 27376928
    [Abstract] [Full Text] [Related]

  • 14. Antimitotic antifungal compound benomyl inhibits brain microtubule polymerization and dynamics and cancer cell proliferation at mitosis, by binding to a novel site in tubulin.
    Gupta K, Bishop J, Peck A, Brown J, Wilson L, Panda D.
    Biochemistry; 2004 Jun 01; 43(21):6645-55. PubMed ID: 15157098
    [Abstract] [Full Text] [Related]

  • 15. Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding.
    Srivastava P, Panda D.
    FEBS J; 2007 Sep 01; 274(18):4788-801. PubMed ID: 17697112
    [Abstract] [Full Text] [Related]

  • 16. Fluorescent aplyronine a: intracellular accumulation and disassembly of actin cytoskeleton in tumor cells.
    Kita M, Yoneda K, Hirayama Y, Yamagishi K, Saito Y, Sugiyama Y, Miwa Y, Ohno O, Morita M, Suenaga K, Kigoshi H.
    Chembiochem; 2012 Aug 13; 13(12):1754-8, 1702. PubMed ID: 22807378
    [No Abstract] [Full Text] [Related]

  • 17. Synthesis and Biological Activities of Aplyronine A Analogues toward the Development of Antitumor Protein-Protein Interaction Inducers between Actin and Tubulin: Conjugation of the C1-C9 Macrolactone Part and the C24-C34 Side Chain.
    Futaki K, Takahashi M, Tanabe K, Fujieda A, Kigoshi H, Kita M.
    ACS Omega; 2019 May 31; 4(5):8598-8613. PubMed ID: 31459949
    [Abstract] [Full Text] [Related]

  • 18. Microtubule-stabilizing activity of zampanolide, a potent macrolide isolated from the Tongan marine sponge Cacospongia mycofijiensis.
    Field JJ, Singh AJ, Kanakkanthara A, Halafihi T, Northcote PT, Miller JH.
    J Med Chem; 2009 Nov 26; 52(22):7328-32. PubMed ID: 19877653
    [Abstract] [Full Text] [Related]

  • 19. Actin-binding marine macrolides: total synthesis and biological importance.
    Yeung KS, Paterson I.
    Angew Chem Int Ed Engl; 2002 Dec 16; 41(24):4632-53. PubMed ID: 12481316
    [Abstract] [Full Text] [Related]

  • 20. [Progress in the study of tubulin inhibitors].
    Shang H, Pan L, Yang S, Chen H, Cheng MS.
    Yao Xue Xue Bao; 2010 Sep 16; 45(9):1078-88. PubMed ID: 21351562
    [Abstract] [Full Text] [Related]

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