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Journal Abstract Search

95 related items for PubMed ID: 2426568

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  • 4. Differing specificities for 4-aminofolate analogues of folylpolyglutamyl synthetase from tumors and proliferative intestinal epithelium of the mouse with significance for selective antitumor action.
    Rumberger BG, Barrueco JR, Sirotnak FM.
    Cancer Res; 1990 Aug 01; 50(15):4639-43. PubMed ID: 2369741
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  • 6. Interaction of polyglutamyl derivatives of methotrexate, 10-deazaaminopterin, and dihydrofolate with dihydrofolate reductase.
    Kumar P, Kisliuk RL, Gaumont Y, Nair MG, Baugh CM, Kaufman BT.
    Cancer Res; 1986 Oct 01; 46(10):5020-3. PubMed ID: 2428470
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  • 7. Novel 6,5-fused ring heterocyclic antifolates: biochemical and biological characterization.
    McGuire JJ, Bergoltz VV, Heitzman KJ, Haile WH, Russell CA, Bolanowska WE, Kotake Y, Haneda T, Nomura H.
    Cancer Res; 1994 May 15; 54(10):2673-9. PubMed ID: 8168096
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  • 8. Analogues of methotrexate in rheumatoid arthritis. 2. Effects of 5-deazaaminopterin, 5,10-dideazaaminopterin, and analogues on type II collagen-induced arthritis in mice.
    Piper JR, DeGraw JI, Colwell WT, Johnson CA, Smith RL, Waud WR, Sirotnak FM.
    J Med Chem; 1997 Jan 31; 40(3):377-84. PubMed ID: 9022805
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  • 9. Folate analogues as inhibitors of thymidylate synthase.
    Brixner DI, Ueda T, Cheng YC, Hynes JB, Broom AD.
    J Med Chem; 1987 Apr 31; 30(4):675-8. PubMed ID: 3470522
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  • 10. Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.
    Allegra CJ, Chabner BA, Drake JC, Lutz R, Rodbard D, Jolivet J.
    J Biol Chem; 1985 Aug 15; 260(17):9720-6. PubMed ID: 2410416
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  • 11. Syntheses and antifolate activity of 5-methyl-5-deaza analogues of aminopterin, methotrexate, folic acid, and N10-methylfolic acid.
    Piper JR, McCaleb GS, Montgomery JA, Kisliuk RL, Gaumont Y, Sirotnak FM.
    J Med Chem; 1986 Jun 15; 29(6):1080-7. PubMed ID: 2423690
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  • 12. Analogues of 10-deazaaminopterin and 5-alkyl-5,10-dideazaaminopterin with the 4-substituted 1-naphthoyl group in the place of 4-substituted benzoyl.
    Piper JR, Ramamurthy B, Johnson CA, Otter GM, Sirotnak FM.
    J Med Chem; 1996 Jan 19; 39(2):614-8. PubMed ID: 8558535
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  • 13. Synthesis and antifolate evaluation of the 10-propargyl derivatives of 5-deazafolic acid, 5-deazaaminopterin, and 5-methyl-5-deazaaminopterin.
    Piper JR, Malik ND, Rhee MS, Galivan J, Sirotnak FM.
    J Med Chem; 1992 Jan 24; 35(2):332-7. PubMed ID: 1732551
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  • 14. Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    Rhee MS, Galivan J, Wright JE, Rosowsky A.
    Mol Pharmacol; 1994 Apr 24; 45(4):783-91. PubMed ID: 7514264
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  • 15. Inhibition of human liver folylpolyglutamate synthetase by non-gamma-glutamylatable antifolate analogs.
    Clarke L, Rosowsky A, Waxman DJ.
    Mol Pharmacol; 1987 Jan 24; 31(1):122-7. PubMed ID: 3807889
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  • 16. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.
    Shih C, Chen VJ, Gossett LS, Gates SB, MacKellar WC, Habeck LL, Shackelford KA, Mendelsohn LG, Soose DJ, Patel VF, Andis SL, Bewley JR, Rayl EA, Moroson BA, Beardsley GP, Kohler W, Ratnam M, Schultz RM.
    Cancer Res; 1997 Mar 15; 57(6):1116-23. PubMed ID: 9067281
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  • 17. Biochemical and cellular pharmacology of 1843U89, a novel benzoquinazoline inhibitor of thymidylate synthase.
    Duch DS, Banks S, Dev IK, Dickerson SH, Ferone R, Heath LS, Humphreys J, Knick V, Pendergast W, Singer S.
    Cancer Res; 1993 Feb 15; 53(4):810-8. PubMed ID: 8428362
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  • 18. Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.
    Westerhof GR, Schornagel JH, Kathmann I, Jackman AL, Rosowsky A, Forsch RA, Hynes JB, Boyle FT, Peters GJ, Pinedo HM.
    Mol Pharmacol; 1995 Sep 15; 48(3):459-71. PubMed ID: 7565626
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  • 19. Enhanced polyglutamylation of aminopterin relative to methotrexate in the Ehrlich ascites tumor cell in vitro.
    Matherly LH, Voss MK, Anderson LA, Fry DW, Goldman ID.
    Cancer Res; 1985 Mar 15; 45(3):1073-8. PubMed ID: 2578870
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  • 20. Predictions of a network thermodynamics computer model relating to the mechanism of methotrexate rescue by 5-formyltetrahydrofolate and to the importance of inhibition of thymidylate synthase by methotrexate-polyglutamates.
    White JC.
    Adv Exp Med Biol; 1983 Mar 15; 163():305-26. PubMed ID: 6193692
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